Results 261 to 270 of about 601,318 (311)

Regional epilepsy: Unraveling the epileptic phenomenon

open access: yes
Epileptic Disorders, EarlyView.
Shreyashish Roy‐Chowdhury   +5 more
wiley   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

open access: yesEpilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Calpastatin, a calpain specific inhibitor, reduce seizures in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy is a chronic condition characterized by unpredictable and recurrent spontaneous seizures. In a previous study, we reported that pharmacological inhibition of calpain prevented epileptogenesis in the rat pilocarpine model. In this study, we demonstrate that transgenic overexpression of calpastatin, the endogenous inhibitor of calpain ...
Philip M. Lam   +3 more
wiley   +1 more source

Hippocampal Zkscan4 confers resilience to chronic stress-induced depression-like behaviors. [PDF]

open access: yesSci Adv
Gao K   +11 more
europepmc   +1 more source

Cardiac structural and molecular alterations in rodent models of temporal lobe epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Cardiac structural and molecular changes are prevalent in people with chronic epilepsy, possibly contributing to an increased risk of premature mortality. However, understanding of the underlying pathophysiological mechanisms is limited.
Zining Liu   +9 more
wiley   +1 more source

Impact of hippocampectomy on seizure freedom in temporal encephaloceles: A systematic review and individual participant data meta‐analysis

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Temporal encephaloceles (TEs) are increasingly recognized as a cause of MRI‐negative temporal lobe epilepsy (TLE). The optimal surgical approach for TE‐related refractory epilepsy remains unclear, particularly regarding the necessity of excluding mesiotemporal structures such as the hippocampus, which may lead to worse ...
Panagiota‐Eleni Tsalouchidou   +4 more
wiley   +1 more source

Dynorphin-A alters the excitability of pyramidal neurons of the rat hippocampus

open access: green, 1983
Donna L. Gruol   +3 more
openalex   +2 more sources

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