Results 281 to 290 of about 776,116 (376)

Anatolian ground squirrel (Spermophilus xanthoprymnus) retina: Comparative expression of synaptophysin, NeuN, calbindin‐D28k, parvalbumin, glial fibrillary acidic protein, and Iba‐1 during pre‐hibernation and hibernation

open access: yesThe Anatomical Record, EarlyView.
Abstract Hibernation induces significant molecular and cellular adaptations in the retina to maintain function under reduced metabolic conditions. This study aimed to investigate the expression of neuronal, synaptic, and glial markers in the retina of Spermophilus xanthoprymnus during pre‐hibernation and hibernation periods using immunohistochemical ...
Mehmet Özbek   +5 more
wiley   +1 more source

A Frank Assessment of SHANK: Impacts of Pathogenic Variations in SHANK3 on Preclinical Models of Phelan McDermid Syndrome

open access: yesAutism Research, EarlyView.
ABSTRACT Although there are as many as 40 preclinical models of the neurodevelopmental disorder Phelan McDermid syndrome (PMS, or 22q13.3 deletion syndrome), detailed phenotypic analyses to compare the effects of different pathogenic variants and inform treatment design are lacking.
Vic Lin   +7 more
wiley   +1 more source

Gut-derived bacterial vesicles carrying lipopolysaccharide promote microglia-mediated synaptic pruning. [PDF]

open access: yesAlzheimers Dement
Zhao X   +15 more
europepmc   +1 more source

Synthesis, Characterization, Biological Properties, and Sensor Applications of Novel Thiosemicarbazone Derivatives

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen   +4 more
wiley   +1 more source

How Growth Cones Sense Extracellular Cues and Drive Neuronal Migration

open access: yesBioEssays, EarlyView.
Migrating neurons and growing axons utilize structurally and functionally similar growth cones to detect guidance cues. Shared receptors and signaling pathways mediate cytoskeletal reorganization to direct movement. This conserved mechanism underlies both neuronal migration and axon extension, providing insights into neuronal development and potential ...
Takahiro Kanzawa   +3 more
wiley   +1 more source

Neural electrodes for brain‐computer interface system: From rigid to soft

open access: yesBMEMat, EarlyView.
Here, we review the development trends of neural electrodes in BCI. This paper highlights the critical role of electrodes in BCI systems, analyzes the limitations of rigid electrodes, and introduces various flexible electrodes. Furthermore, we discuss application scenarios and prospects of BCI electrode technology, aiming to provide valuable references
Dan Yang   +7 more
wiley   +1 more source

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