Results 291 to 300 of about 804,912 (360)

Reviewer #1 (Public review): Event boundaries drive norepinephrine release and distinctive neural representations of space in the rodent hippocampus

Sam McKenzie, Alexandra L Sommer, Tia N Donaldson, Infania Pimentel, Meenakshi Kakani, Irene Jungyeon Choi, Ehren L Newman, Daniel F English   +7 more
openalex   +1 more source

Association between Human Leukocyte Antigen Alleles and Neuropathological Outcomes in Lewy Body Disease

Annals of Neurology, EarlyView.
Objective Lewy body disease (LBD) is a complex neurodegenerative disorder characterized by the accumulation of misfolded α‐synuclein in the brain. Neuroinflammation has long been implicated in LBD pathogenesis, and recent genetic studies in Parkinson's disease (a clinical manifestation of LBD) have shown consistent association with the human leukocyte ...
Marios Gavrielatos, Michael G. Heckman, Alexandra I. Soto‐Beasley, Sophia G. Blumenfeld, Xu Hou, Shunsuke Koga, Melissa E. Murray, Koji Kasanuki, Daisuke Ono, Fabienne C. Fiesel, Ryan J. Uitti, Julie A. Fields, Hugo Botha, Vijay K. Ramanan, Kejal Kantarci, Val J. Lowe, Clifford R. Jack, Nilufer Ertekin‐Taner, J. Raphael Gibbs, Bryan J. Traynor, Clifton L. Dalgard, Rodolfo Savica, Jonathan Graff‐Radford, Ronald C. Petersen, R. Ross Reichard, Neill R. Graff‐Radford, Tanis J. Ferman, Bradley F. Boeve, Zbigniew K. Wszolek, Wolfdieter Springer, Ziv Gan‐Or, Emmanuel Mignot, Sonja W. Scholz, Dennis W. Dickson, Owen A. Ross   +34 more
wiley   +1 more source

Epigenetic and transcriptomic alterations precede amyloidosis in the Alzheimer's disease App^NL-G-F knock-in mouse model. [PDF]

Sci Rep
Okhovat M, Layman CE, Davis BA, Pederson A, O'Niel A, Holden S, Kessler K, Acharya SN, Wheeler KJ, Nevonen KA, Herrera J, Ward S, Vigh-Conrad K, Adey A, Raber J, Carbone L.   +15 more
europepmc   +1 more source

Timing of Peri‐Ictal MRI Abnormalities in Status Epilepticus – One Size Does Not Fit All

Annals of Neurology, EarlyView.
Objective We aimed to investigate timing of occurrence of peri‐ictal MRI abnormalities – a potential risk biomarker of status epilepticus‐related cerebral injury (t2). Methods This prospective study enrolled adult patients with status epilepticus and acute magnetic resonance imaging (MRI); patients with peri‐ictal MRI abnormalities underwent follow‐up ...
Pilar Bosque Varela, Lukas Machegger, Tanja Prüwasser, Wanda Lauth, Jürgen Steinbacher, Andreas Oellerer, Georg Zimmermann, Johannes Pfaff, Mark McCoy, Bernardo Crespo Pimentel, Markus Leitinger, Eugen Trinka, Giorgi Kuchukhidze   +12 more
wiley   +1 more source

Aquaporin-4 and caveolin-1 as mediators of fibrinogen-driven cerebrovascular pathology in cerebral amyloid angiopathy. [PDF]

Alzheimers Dement
Singh V, Rochakim N, Ferraresso F, Garg K, Rizvi AB, Choudhury A, Kastrup CJ, Ahn HJ.   +7 more
europepmc   +1 more source

Anatomical Progression of Neuropathology in FTLD‐TDP Type C and Linkage to Annexin A11

Annals of Neurology, EarlyView.
Objective Frontotemporal lobar degenerations (FTLD)‐TDP type C (TDP‐C) is distinguished from other FTLD‐TDP subtypes by 3 unique features: (1) invariable onset in the anterior temporal lobe (ATL), (2) phosphorylated TDP‐43 (pTDP) neurites in cortex, and (3) colocalization of all pTDP deposits with annexin A11 (ANXA11).
Allegra Kawles, Caroline Nelson, Ivan Ayala, Elena Barbieri, Rudolph Castellani, Changiz Geula, Tamar Gefen, M. Marsel Mesulam   +7 more
wiley   +1 more source

Regional and temporal dynamics of DNA methylation and epigenetic gene regulation in response to binge-like alcohol exposure in the adolescent mouse brain. [PDF]

Front Mol Neurosci
Cherif A, Bourzam A, Fridhi Z, Boukhawiye H, Guillou C, Cosette P, Zekri S, Leprince J, Vaudry D, Masmoudi-Kouki O.   +9 more
europepmc   +1 more source

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

Annals of Neurology, EarlyView.
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi, John Williamson, Huayu Sun, Suchitra Joshi, Rachel Jane Spera, Savaira Zaib, Supriya Sharma, Chengsan Sun, Andrey Brodovskiy, Ifrah Zawar, Jaideep Kapur   +10 more
wiley   +1 more source

Metformin Ameliorates Cognitive Deficits and Neuroinflammation in a Mouse Model of Familial Hypercholesterolemia. [PDF]

Neurochem Res
do Nascimento NB, Farias HR, Schons T, Padilha APZ, Costa MV, Peres AM, da Silva LDS, Dantas RM, Ramos JMO, Rodrigues MS, Telles F, Guma FTCR, Moreira JCF, Bast RKSS, de Bem AF, de Oliveira J.   +15 more
europepmc   +1 more source