Results 31 to 40 of about 523,769 (311)
N6-methyladenosine participates in mouse hippocampus neurodegeneration via PD-1/PD-L1 pathway
Frontiers in Neuroscience, 2023 Developmental abnormalities and hippocampal aging leads to alteration in cognition. In the brain, N6-methyladenosine (m6A) is a common and reversible mRNA alteration that is essential for both neurodevelopment and neurodegeneration. However, its function
Wen Hu +6 more
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Memory, Visual Discrimination Performance, and the Human Hippocampus
Journal of Neuroscience, 2011 We evaluated recent proposals that the hippocampus supports certain kinds of visual discrimination performance, for example, when spatial processing is required and the stimuli have a high degree of feature overlap.
Soyun Kim +5 more
semanticscholar +1 more source
WikiJournal of Medicine, 2017 The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος hippos, "horse" and κάμπος kampos, "sea monster") is a major component of the brains of humans and other vertebrates.
Marion Wright
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Frontiers in Psychiatry, 2021 Learning is a critical behavioral process that is influenced by many neurobiological systems. We and others have reported that acetylcholinergic signaling plays a vital role in learning capabilities, and it is especially important for contextual fear ...
Sean M. Mooney-Leber +7 more
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Hormones and the hippocampus [PDF]
Journal of Endocrinology, 2001 Hippocampal lesions produce memory deficits, but the exact function of the hippocampus remains obscure. Evidence is presented that its role in memory may be ancillary to physiological regulation. Molecular studies demonstrate that the hippocampus is a primary target for ligands that reflect body physiology, including ion balance and blood pressure ...
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Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus
Journal of Neuroscience, 2000 Recent studies suggest that stress-induced atrophy and loss of hippocampal neurons may contribute to the pathophysiology of depression. The aim of this study was to investigate the effect of antidepressants on hippocampal neurogenesis in the adult rat ...
J. Malberg +3 more
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Frontiers in Human Neuroscience, 2016 Behavioral studies have reported that males perform better than females in 3-dimensional (3D) mental rotation. Given the important role of the hippocampus in spatial processing, the present study investigated whether structural differences in the ...
Wei Wei +6 more
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Aerobic Exercise, Cardiorespiratory Fitness, and the Human Hippocampus
Hippocampus, 2021 The hippocampus is particularly susceptible to neurodegeneration. Physical activity, specifically increasing cardiorespiratory fitness via aerobic exercise, shows promise as a potential method for mitigating hippocampal decline in humans.
Sarah L. Aghjayan +5 more
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Diffusion MRI of the Hippocampus
The Journal of Neuroscience, 2023 The hippocampus is a brain structure that plays key roles in a variety of cognitive processes. Critically, a wide range of neurological disorders are associated with degeneration of the hippocampal microstructure, defined as neurons, dendrites, glial cells, and more.
Bradley G. Karat +2 more
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The hippocampus and depression
European Psychiatry, 2002 SummaryThe effect of depression on the hippocampus has become the focus of a number of structural and functional neuroimaging studies. In the past two decades, advances in neuroimaging techniques now allow the examination of subtle changes in both regional structure and function that are associated with the pathophysiology of depression.
Y I, Sheline, B L, Mittler, M A, Mintun
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