Results 41 to 50 of about 324,234 (265)

The hippocampus and depression

European Psychiatry, 2002
SummaryThe effect of depression on the hippocampus has become the focus of a number of structural and functional neuroimaging studies. In the past two decades, advances in neuroimaging techniques now allow the examination of subtle changes in both regional structure and function that are associated with the pathophysiology of depression.
Y I, Sheline, B L, Mittler, M A, Mintun
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Hippocampus hippocampus hippocampus (Linnaeus 1758

, 2014
Published as part of Carneiro, Miguel, Martins, Rogélia, Landi, Monica & Costa, Filipe O., 2014, Updated checklist of marine fishes (Chordata: Craniata) from Portugal and the proposed extension of the Portuguese continental shelf, pp. 1-73 in European Journal of Taxonomy 73 on page 45, DOI: 10.5852/ejt.2014.73, http://zenodo.org/record ...
Carneiro, Miguel, Martins, Rogélia, Landi, Monica, Costa, Filipe O.   +3 more
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Symptomatic remission and hippocampus volume in schizophrenia

Psychiatry and Clinical Psychopharmacology, 2021
Objective: A recent meta-analysis of brain structure studies in schizophrenia has demonstrated that the most commonly reported deficit in brain regions was in left medial temporal lobe, which contains the hippocampus.
Ping Tsun Chang, Jiing Feng Lirng, Yuan Hwa Chou   +2 more
doaj  

Dorsal and Ventral Hippocampus Differentiate in Functional Pathways and Differentially Associate with Neurological Disease-Related Genes during Postnatal Development

Frontiers in Molecular Neuroscience, 2017
The dorsal and ventral regions of the hippocampus are important in cognitive and emotional processing, respectively. Various approaches have revealed the differential molecular and structural characteristics, and functional roles of the hippocampus ...
A-Ram Lee, Jong-Hwan Kim, Jong-Hwan Kim, Eunsil Cho, Eunsil Cho, Mirang Kim, Mirang Kim, Mikyoung Park, Mikyoung Park   +8 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Dietary magnesium deficiency induces the expression of neuroinflammation‐related genes in mouse brain

Neuropsychopharmacology Reports, 2021
Aims Dietary Mg2+ deficiency (MgD) impairs hippocampus‐dependent memory in mice; however, the molecular mechanisms underlying MgD‐induced memory impairments are unclear.
Ryuhei Tsuji, Hirofumi Inoue, Mariko Uehara, Satoshi Kida   +3 more
doaj   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

The microbiota-gut- hippocampus axis

Frontiers in Neuroscience, 2022
IntroductionIt is well known that the intestinal bacteria substantially affect physiological processes in many body organs. Especially, through a bidirectional communication called as gut-microbiota-brain axis, the gut microbiota deeply influences ...
Mahmoud Salami, Masoud Soheili
doaj   +1 more source

Prediction, sequences and the hippocampus [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2009
Recordings of rat hippocampal place cells have provided information about how the hippocampus retrieves memory sequences. One line of evidence has to do with phase precession, a process organized by theta and gamma oscillations. This precession can be interpreted as the cued prediction of the sequence of upcoming positions.
John, Lisman, A D, Redish
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