Results 11 to 20 of about 935 (164)

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis

BJU International, EarlyView.
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon, Asaad Ahmad, Natalie Lott, Alison Blatt   +3 more
wiley   +1 more source

First Description and Characterisation of Lactococcus garvieae Strains Causing Septicaemic Disease in Farmed Sea Bass (Dicentrarchus labrax; Linnaeus) in Spain

Journal of Fish Diseases, EarlyView.
ABSTRACT This study presents the first description and characterisation of Lactococcus garvieae isolated from diseased European sea bass (Dicentrarchus labrax) farmed in Spain. During autumn 2023, two fish farms were affected by infectious outbreaks causing moderate cumulative fish mortality (5%–10%). Diseased fish showed clinical signs of haemorrhagic
Belén Fouz, Evelyn Carballeda‐Carrasco, Javier Barriga‐Cuartero, Yolanda Torres‐Corral, Álvaro Robles, Carlos Zarza, Ysabel Santos   +6 more
wiley   +1 more source

From Dismissal to Partnership: Patient Experiences of Recurrent Urinary Tract Infection Healthcare Informed by the Theoretical Domains Framework and Behaviour Change Theory

Health Expectations, Volume 29, Issue 2, April 2026.
ABSTRACT Background Recurrent urinary tract infection (rUTI) is common, debilitating, and associated with substantial negative impact on quality of life. Despite this, rUTI healthcare is often experienced as fragmented, dismissive, and poorly aligned with patient needs.
Abigail F. Newlands, Melissa L. Kramer, Sarah Snuggs, Katherine A. Finlay   +3 more
wiley   +1 more source

First Detection of Lactococcus formosensis subsp. formosensis in Rainbow Trout (Oncorhynchus mykiss) in Europe

Journal of Fish Diseases, Volume 49, Issue 4, April 2026.
ABSTRACT Lactococcus garvieae, Lactococcus petauri and Lactococcus formosensis are etiological agents of piscine lactococcosis, a disease reported in Italy since the early 1990s and linked to significant aquaculture losses. To the best of our knowledge, this study reports the first detection of L. formosensis subsp. formosensis in farmed rainbow trout (
Silvia Colussi, Giuseppe Esposito, Khalid Shahin, Pier Luigi Acutis, Lucio Fariano, Claudio Ghittino, Maria Goria, Fabio Bondavalli, Paolo Ajmone Marsan, Giorgia Bignami, Elena Bozzetta, Marino Prearo, Paolo Pastorino   +12 more
wiley   +1 more source

Treatment outcomes of multidisciplinary management of recurrent urinary tract infections: A 2‐year experience in a dedicated complex‐UTI clinic

BJUI Compass, Volume 7, Issue 3, March 2026.
Abstract Objectives This work aimed to assess treatment outcomes in patients with recurrent urinary tract infections (rUTIs) managed in a dedicated multidisciplinary complex‐UTI clinic. In addition, this work aimed to evaluate the impact of tailored interventions on patient‐reported outcomes, including quality of life (QoL) and symptomatic improvement.
Pragnitha Chitteti, Ekpeno Inyang, Ahmed Ghonaimy, Jayne Morris‐Laverick, Stephanie Bezemer, Igor Kubelka, Victoria McCune, Mehwash Nadeem   +7 more
wiley   +1 more source

A Multi‐Organ Atlas Links Gut Microbial Metabolites to Systemic Redox Changes in Aging Mice

Aging Cell, Volume 25, Issue 3, March 2026.
A gut‐derived metabolic signature drives systemic aging phenotypes. Integrated multi‐omics profiling of young versus aged mice identifies a conserved aging signature characterized by the depletion of protective lysophosphatidylcholines (LPC 22:0) and the concurrent accumulation of pro‐oxidative microbial catabolites (TMAO, IAA).
Sanaullah Sajid, Jieliang Huang, Shaofang Kong, Chengze Lai, Zhuoxin Tan, Yiming Shao, Lianxian Guo   +6 more
wiley   +1 more source

Effect of COVID‐19 Pandemic on Epidemiology and Antimicrobial Susceptibility of Campylobacter Species, Salmonella enterica and Yersinia enterocolitica in Southwest Finland 2018–2022

APMIS, Volume 134, Issue 3, March 2026.
ABSTRACT This study investigated the effect of the COVID‐19 pandemic on the epidemiology and antimicrobial susceptibility of fecal Campylobacter spp., Salmonella enterica, and Yersinia enterocolitica strains in Southwest Finland from 2018 to 2022. Results show that the number of travel‐associated S. enterica and Campylobacter spp.
Tanja Orpana, Teemu Kallonen, Antti J. Hakanen, Marianne Gunell   +3 more
wiley   +1 more source

1H‐Nuclear Magnetic Resonance Metabolic Profiling of Pantaneiro and Curraleiro Beef Breeds: Unveiling Adaptation Mechanisms in Brazilian Livestock

New Zealand Journal of Agricultural Research, Volume 69, Issue 1, February 2026.
This study provides the first metabolomic characterization of serum from Pantaneiro and Curraleiro beef cattle, unveiling their unique adaptations to the Pantanal and Cerrado biomes of Brazil. Blood was collected during the summer season to capture metabolic responses to extreme environmental conditions, including high temperatures and varying humidity.
Eduardo Solano Pina dos Santos, Vinicius Laerte Silva Herreira, Ana Laura dos Santos Munhoz Gôngora, Gabriel Henrique Ribeiro, Luiz Alberto Colnago, Brenda Santos de Oliveira, Fernanda Maria Marins Ocampos, Alanne Tenório Nunes, Yasmin Gonçalves da Silva de Souza, Rafael Henrique de Tonissi e Buschinelli de Góes, Yash Dixit, Marlon Martins Reis, Nara Regina Brandão Cônsolo   +12 more
wiley   +1 more source