Results 11 to 20 of about 9,336,073 (253)

Neuroimmune regulation in Hirschsprung’s disease associated enterocolitis

open access: yesFrontiers in Immunology, 2023
Neuroimmune pathways are important part of the regulation of inflammatory response. Nerve cells regulate the functions of various immune cells through neurotransmitters, and then participate in the inflammatory immune response. Hirschsprung’s disease (HD)
Haosen Ji, Dengming Lai, Jinfa Tou
doaj   +2 more sources

Maternal use of selective serotonin reuptake inhibitors during pregnancy is associated with Hirschsprung’s disease in newborns – a nationwide cohort study

open access: yesOrphanet Journal of Rare Diseases, 2017
Background Hirschsprung’s disease is a rare condition caused by congenital malformation of the gastrointestinal tract affecting 1:5000 children. Not much is known about risk factors for development of Hirschsprung’s disease.
Sebastian Werngreen Nielsen   +4 more
doaj   +2 more sources

SLIT2/ROBO1-miR-218-1-RET/PLAG1: a new disease pathway involved in Hirschsprung\u27s disease. [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2015
Hirschsprung\u27s disease (HSCR) is a rare congenital disease caused by impaired proliferation and migration of neural crest cells. We investigated changes in expression of microRNAs (miRNAs) and the genes they regulate in tissues of patients with HSCR ...
Geng, Qiming   +12 more
core   +4 more sources

The follow-up of the robotic-assisted Soave procedure for Hirschsprung’s disease in children

open access: yesJournal of Robotic Surgery, 2021
Robotic surgery offers three-dimensional visualization and precision of movement that could be of great value to gastrointestinal surgeons. There were many previous reports on robotic technology in performing Soave colonic resection and pull-through for ...
T. A. Quynh   +5 more
semanticscholar   +1 more source

ERNICA guidelines for the management of rectosigmoid Hirschsprung’s disease

open access: yesOrphanet Journal of Rare Diseases, 2020
Background Hirschsprung’s disease (HSCR) is a serious congenital bowel disorder with a prevalence of 1/5000. Currently, there is a lack of systematically developed guidelines to assist clinical decision-making regarding diagnostics and management.
K. Kyrklund   +19 more
semanticscholar   +1 more source

Molecular Genetic Anatomy and Risk Profile of Hirschsprung's Disease

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Hirschsprung's disease, or congenital aganglionosis, is a developmental disorder of the enteric nervous system and is the most common cause of intestinal obstruction in neonates and infants.
Joseph Tilghman   +13 more
semanticscholar   +1 more source

Current status of intestinal transplantation in children [PDF]

open access: yes, 1998
Purpose: A clinical trial of intestinal transplantation (Itx) under tacrolimus and prednisone immunosuppression was initiated in June 1990 in children with irreversible intestinal failure and who were dependent on total parenteral nutrition (TPN ...
Asfar   +52 more
core   +1 more source

Significance of neurexin and neuroligin polymorphisms in regulating risk of Hirschsprung’s disease

open access: yesJournal of Investigative Medicine, 2018
C-type natriuretic peptide (CNP) is regarded as a local, paracrine hormone to regulate vascular tone and cell proliferation. Although several in vivo studies have documented that CNP exerts the inhibitory effects on mesangial cells (MCs) proliferation ...
M. Borga   +6 more
semanticscholar   +1 more source

Delayed diagnosis of Hirschsprung's disease associated with colonic atresia and multiple anomalies: Report of a case and review of the literature

open access: yesJournal of Pediatric Surgery Case Reports, 2016
The co-occurrence of colonic atresia and Hirschsprung's disease is extremely rare and presents a diagnostic and therapeutic challenge. Although colonic atresia is usually recognized shortly after birth, the diagnosis of co-existent Hirschsprung's disease
Jinyoung Park
doaj   +1 more source

A rare association of ileal atresia and total colonic Hirschsprung's disease

open access: yesJournal of Pediatric Surgery Case Reports, 2022
Total colonic aganglionosis is the most rare form of Hirschsprung's disease and is defined as the absence of ganglion cells in both myenteric and submucosal plexus extending from the anus to at least the ileocecal valve. Intrauterine intussusceptions, on
Aida Daib   +5 more
doaj   +1 more source

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