Results 11 to 20 of about 9,333,061 (296)

Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation

Nature Communications, 2023
Hirschsprung disease is characterized by the absence of enteric neurons caused by the defects of enteric neural crest cells, leading to intestinal obstruction.
Zhixin Li, Kathy Nga-Chu Lui, Sin-Ting Lau, Frank Pui-Ling Lai, Peng Li, Patrick Ho-Yu Chung, Kenneth Kak-Yuen Wong, Paul Kwong-Hing Tam, Maria-Mercedes Garica-Barcelo, Chi-Chung Hui, Pak Chung Sham, Elly Sau-Wai Ngan   +11 more
doaj   +2 more sources

Alterations of Gut Bacteria in Hirschsprung Disease and Hirschsprung-Associated Enterocolitis

Microorganisms, 2021
Hirschsprung-associated enterocolitis (HAEC) is a common life-threatening complication of Hirschsprung disease (HSCR). It has been proposed that gut microbiota, which have an essential role in gut-homeostasis, are associated with HAEC.
Sireekarn Chantakhow, Jiraporn Khorana, Kanokkan Tepmalai, Nonglak Boonchooduang, Nipon Chattipakorn, Siriporn C. Chattipakorn   +5 more
doaj   +2 more sources

Hirschsprung disease: current perspectives

Open Access Surgery, 2016
SW Moore Division of Paediatric Surgery, Faculty of Medicine, University of Stellenbosch, Cape Town, South Africa Abstract: Hirschsprung disease is a complex congenital condition of the intestine, which is recognized as being of genetic origin and ...
Moore SW
doaj   +2 more sources

The Emerging Genetic Landscape of Hirschsprung Disease and Its Potential Clinical Applications

Frontiers in Pediatrics, 2021
Hirschsprung disease (HSCR) is the leading cause of neonatal functional intestinal obstruction. It is a rare congenital disease with an incidence of one in 3,500–5,000 live births.
Anwarul Karim, C. Tang, P. Tam
semanticscholar   +1 more source

Anorectal malformation and Hirschsprung disease in an otherwise healthy infant

Journal of Pediatric Surgery Case Reports, 2022
Background: Hirschsprung disease and anorectal malformations are two conditions that are rarely associated with one another. Current reports of anorectal malformations with concurrent Hirschsprung disease predominantly describe children with genetic ...
Audra Rougraff, Britney L. Grayson, Alan P. Ladd   +2 more
doaj   +1 more source

Prevalence of Hirschsprung-associated enterocolitis in patients with Hirschsprung disease

Pediatric surgery international (Print), 2021
Purpose Hirschsprung's associated enterocolitis (HAEC) is a complication of Hirschsprung's Disease (HD) with considerable morbidity and mortality. The variability in presentation leads to a wide variety of the reported prevalence pre-and postoperatively.
J. Hagens, K. Reinshagen, C. Tomuschat
semanticscholar   +1 more source

Application of toluidine blue stain and neuron specific enolase immunohistochemical stain in the diagnosis of hirschsprung disease

Bangabandhu Sheikh Mujib Medical University Journal, 2023
Hirschsprung disease is one of the most common and problematic infancy and childhood maladies. Early and accurate diagnosis is a fundamental step in proper management and prevention of complications.
Tasmia Islam, Sultana Gulshana Banu, Bishnu Pada Dey, Mohammad Mosiur Rahman, Papiya Rahman, Ummey Salma Shabnam, Syeeda Shiraj Um Mahmuda   +6 more
doaj   +1 more source

Colonic atresia and hirschsprung disease: a case report and review of the literature

Journal of Medical Case Reports, 2023
Background Colon atresia is one of the rarest congenital anomalies of the gastrointestinal tract, with an incident range of between 1 in 10,000 and 66,000 live births.
Amirhossein Ladan, Reza Mahdian Jouybari, Mahnaz Zareh Akbari, Pegah Moharrami Yeganeh   +3 more
doaj   +1 more source

New mutations associated with Hirschsprung disease

Anales de Pediatría (English Edition), 2020
Introduction: Hirschsprung Disease is caused by an impairment in cell migration from the neural crest to the gastrointestinal tract, resulting in an absence of neurons in the myenteric plexus.
Marta Lorente-Ros, Ane Miren Andrés, Alba Sánchez-Galán, Cinthia Amiñoso, Sixto García, Pablo Lapunzina, Jesús Solera-García   +6 more
doaj   +1 more source

Perioperative outcomes of neonatal versus delayed surgery for Hirschsprung disease: a nationwide retrospective cohort study in Japan. [PDF]

Pediatr Surg Int
Kutsukake M, Aso S, Konishi T, Fujiogi M, Takamoto N, Yanagida Y, Morita K, Fushimi K, Matsui H, Yasunaga H, Fujishiro J.   +10 more
europepmc   +3 more sources