Results 31 to 40 of about 816 (186)

Retention of critical platelet hemostatic functions of amotosalen‐UVA pathogen‐reduced cryoprecipitated fibrinogen complex

Transfusion, Volume 66, Issue 2, Page 393-404, February 2026.
Abstract Background Cryoprecipitate Anti‐Haemophilic Factor (CRYO‐AHF) is enriched for fibrinogen, VWF, FVIII, FXIII and fibronectin, but has short post‐thaw expiration due to risk of transfusion‐transmitted infection (TTI) limiting availability for rapid treatment.
Florian Tupin, Clarisse Mouriaux, Michelle Gatmaitan, Kaja Kaastrup, Subramanian Yegneswaran, Laurence Corash, Pierre H. Mangin   +6 more
wiley   +1 more source

Comparative genomics of three non-hematophagous leeches (<i>Whitmania</i> spp.) with emphasis on antithrombotic biomolecules. [PDF]

Front Genet
Leeches are well known for blood-feeding habits and are widely used for medicinal purposes as they secrete various antithrombotic substances. However, some leeches exhibit non-hematophagous habits and their significance for medicinal use is controversial.
Zhao F, Huang Z, Tang L, Zhang W, Liu Z, Lin G.   +5 more
europepmc   +3 more sources

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, Volume 13, Issue 4, 19 January 2026.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

Advanced Science, Volume 13, Issue 6, 30 January 2026.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu, Gaofeng Li, Wenyi Wan, Jinsheng Li, Ge Yan, Shijie Wang, Xiuqi Hu, Zongqi Han, Yazheng Shan, Ying Zhou, Nianguo Dong, Weihua Qiao   +11 more
wiley   +1 more source

Technical report on the environmental monitoring of the cage area at the Source of the Nile (SON) Fish Farm for quarter 2: April-June 2011 [PDF]

, 2011
Source of the Nile Fish farm (SON) is located at Bugungu area in Napoleon Gulf, northern Lake Victoria. The proprietors of the farm requested for technical assistance of NaFIRRI to undertake regular environment monitoring of the cage site as is mandatory
Kiggundu, V., Magezi, G., Naluwairo, J., Ndawula, L.M., Ocaya, H., Olokotum, M., Pabire Ghandi, W., Wandera, S.B.   +7 more
core  

Anticoagulation for patients with heparin-induced thrombocytopenia using recombinant hirudin during cardiopulmonary bypass [PDF]

, 2002
Heparin-induced thrombocytopenia (HIT) is a common complication of heparin therapy. There are three types of HIT. In the majority of patients, thrombocytopenia is modest and resolves without sequelae (HIT I).
Fleming, Neal W, Liu, Hong, Moore, Peter G   +2 more
core   +1 more source

eVLP‐Mediated Cas9 Delivery for Preventing IBMIR in Islet Transplantation

Small, Volume 22, Issue 1, 2 January 2026.
Engineered virus‐like particles (eVLPs) are used to deliver Cas9 nuclease to knock out tissue factor (TF) and plasminogen activator inhibitor‐1 (PAI‐1) genes in pancreatic islets. The edited islets maintained viability and function, while reducing instant blood‐mediated inflammatory reaction (IBMIR) markers and improving glycemic control in diabetic ...
Manju Shrestha, Yeonji Kim, Subin Park, Hu‐Lin Jiang, Jae‐Young Lee, Daesik Kim, Jee‐Heon Jeong   +6 more
wiley   +1 more source

Simple and efficient methods for isolation and activity measurement of the recombinant hirudin variant 3 from Bacillus subtilis [PDF]

, 2013
A simple purification approach of the recombinant hirudin variant 3 from the Bacillus subtilis was established, by which the hirudin could be purified to the purity of 95% through one-step chromatography with the total recovery rate of 83.9%.
Chen, HY, Lu, J, Qi, XH, Xu, QG, Zhang, JH, Zhu, DC   +5 more
core   +2 more sources

Testicular Compartment Syndrome Post Bilateral Microdissection Testicular Sperm Extraction: A Case Report and Review of the Current Literature

Case Reports in Urology, Volume 2026, Issue 1, 2026.
Background Testicular compartment syndrome (TCS) is a rare phenomenon with around 14 cases reported in the literature. It occurs when extraluminal compression or increased venous resistance leads to raised intratesticular pressure. The fibrous tunica albuginea covering the testes does not distend, meaning the pressure is not relieved and compartment ...
Catherine Larard, Katie McComb, Ivo Donkov, Alberto Coscione, Panagiotis Nikolinakos, Karl H. Pang, Suraiya Saleem   +6 more
wiley   +1 more source

Laryngeal Leech as a Live Foreign Body: Case Reports and a Safe Removal Technique

Case Reports in Otolaryngology, Volume 2026, Issue 1, 2026.
Leech infestation in the larynx is a rare condition with serious implications due to airway obstruction and persistent bleeding. This report presents two cases of dysphonia and hemoptysis caused by laryngeal leeches after consuming contaminated water.
Mahdieh Mohebbi, Ali Ghasemi, Saeed Sohrabpour, Reza Erfanian, Farrokh Heidari, Dina Mousavi-Asl, Benyamin Mousavi-Asl, Raut Nivedita   +7 more
wiley   +1 more source