Results 31 to 40 of about 1,252 (164)
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.ABSTRACT Hyperuricemia, characterized by elevated serum uric acid (SUA) levels, is increasingly recognized as a pathological contributor to renal injury through oxidative stress, inflammation, and apoptosis. Hirudin, a thrombin inhibitor derived from leech saliva, has recently been noted for its anti‐inflammatory properties, yet its role in ...
Yingxue Zhao +8 more
wiley +1 more source
Ras activation in Hirudo medicinalis angiogenic process [PDF]
Invertebrate Survival Journal, 2013 In some leeches like Hirudo medicinalis, any kind of stimulation (surgical wound or growth factor injection) provokes the botryoidal tissue response. This peculiar tissue, localized in the loose connective tissue between gut and body wall, is formed by ...
R Valvassori +4 more
doaj +2 more sources
Advanced Electronic Materials, Volume 12, Issue 14, 20 July 2026.Invertebrates are the classic neuroscience models and should make a comeback. Invertebrate organisms can be a more ethical and cost‐effective way to move bioelectronics research forward more rapidly. ABSTRACT The accelerating development of bioelectronic neural interfaces has brought increased attention to ethical considerations surrounding in vivo ...
Eric Daniel Głowacki
wiley +1 more source
Scientific Reports, 2023 Hirudin is a pharmacologically active substance in leeches with potent blood anticoagulation properties. Although recombinant hirudin production isolated from Hirudo medicinalis Linnaeus and Hirudinaria manillensis Lesson is known, to our knowledge, this
Ping Shi +5 more
doaj +1 more source
Feeding Strategy Shapes the Evolution of the Hyaluronidase Gene Family in Medicinal Leeches
Ecology and Evolution, Volume 16, Issue 7, July 2026.We investigated the molecular evolution and expression divergence of the hyaluronidase gene family across eight medicinal leech species with contrasting feeding strategies. Hematophagous species retained a complete five‐member gene repertoire and exhibited elevated dN/dS values and significantly elevated gene expression compared to non‐hematophagous ...
Rujiao Sun +9 more
wiley +1 more source
Systematic review of medicinal leech therapy in urology
African Journal of Urology, 2023 Background Medicinal leech therapy, otherwise known as hirudotherapy or leeching, has been utilized for numerous pathologies over centuries. The technique resurfaced in modern medicine for its beneficial effects in microsurgical complications ...
Alexander O. Battin +2 more
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Blue plaque review series: Thomas Graham Brown: Before his time
Experimental Physiology, Volume 111, Issue 7, Page 3191-3202, 1 July 2026.Abstract Thomas Graham Brown made a seminal discovery, published in 1911 while he was a Carnegie Fellow in the University of Liverpool laboratory of Nobel Prize winner Charles S. Sherrington. Working in cats, he showed that rhythmic ‘voluntary’ behaviour, such as stepping and, by inference, walking, does not result from a chain of reflex events, but ...
Ronald L. Calabrese, Eve Marder
wiley +1 more source
Naragh Suburb, Center of Iran; A Natural Habitat of Hirudo medicinalis
International Archives of Health Sciences, 2014 Aims A very common species of leeches has been named as Hirudo medicinalis. Regarding to the application of leeches in medicine and their fast extinction, this study was performed in aquatic habitats of Kashan aimed to determine the distribution of ...
Dehghani R.1 PhD, +3 more
doaj
The Historical and Overlooked Collapse of Medicinal Leeches in Spain
Aquatic Conservation: Marine and Freshwater Ecosystems, Volume 36, Issue 3, March 2026.ABSTRACT Leeches in genus Hirudo have been used in medicine since ancient times, but increased exploitation during the 19th century led to the depletion of several populations in Europe. A compilation of Hirudo records in Spain (H. troctina Johnson, 1816 and H. verbana Carena, 1820) show that the genus was more commonly mentioned and widely distributed
Francisco Blanco‐Garrido +2 more
wiley +1 more source
Medicinal leeches extract at complex treatment of experimental acute myocardial infarction in rats
КардиоСоматика, 2015 Creating of pharmacological forms based on the medicinal leech extract is a perspective decision of various clinical pathologies. To introduce a new drug into clinical practice is need to investigate its influence on the treatment effectivity at ...
G. I Nikonov +2 more
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