Results 41 to 50 of about 802 (158)

Identification and characterization of hirudin-HN, a new thrombin inhibitor, from the salivary glands of Hirudo nipponia [PDF]

open access: yesPeerJ, 2019
Transcriptome sequencing data (6.5 Gb) of the salivary glands of the haematophagous leech Hirudo nipponia was obtained by using the BGIseq-500 platform.
Boxing Cheng   +6 more
doaj   +2 more sources

Multi‐Target Mechanisms of the Naofucong in Ameliorating Diabetes‐Associated Cognitive Dysfunction via cAMP/PKA/CREB‐Mediated Synaptic and Inflammatory Regulation

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
Naofucong exerts multi‐target neuroprotective effects by activating the cAMP/PKA/CREB pathway and coordinately regulating synaptic plasticity and neuroinflammation. ABSTRACT Objective Diabetes‐associated cognitive dysfunction (DACD) is a prevalent and debilitating complication of diabetes, yet effective therapies remain limited. The traditional Chinese
Mei Ma   +4 more
wiley   +1 more source

Medicinal leeches extract at complex treatment of experimental acute myocardial infarction in rats

open access: yesКардиоСоматика, 2015
Creating of pharmacological forms based on the medicinal leech extract is a perspective decision of various clinical pathologies. To introduce a new drug into clinical practice is need to investigate its influence on the treatment effectivity at ...
G. I Nikonov   +2 more
doaj  

ACETYL-L-CARNITINE AFFECTS THE ELECTRICAL ACTIVITY OF MECHANOSENSORY NEURONS IN HIRUDO MEDICINALIS GANGLIA

open access: yesEuromediterranean Biomedical Journal, 2017
Was previously discovered that in the leech Hirudo medicinalis, acetyl-l-carnitine (ALC) affects forms of non-associative learning, such as sensitization and dishabituation, due to nociceptive stimulation of the dorsal skin in the swim induction ...
Giovanna Traina
doaj   +1 more source

Predictive Distribution Modeling of the Medicinal Leech Hirudo verbana Carena, 1820 (Hirudinea, Hirudinidae) in Sicily: Implications for Conservation

open access: yesEcology and Evolution, Volume 15, Issue 11, November 2025.
A predictive distribution model for Hirudo verbana in Sicily was developed using 1980–2024 occurrence data and environmental variables. The species is associated with densely vegetated, high‐elevation lentic habitats and avoids human‐disturbed areas.
Mirko Liuzzo   +2 more
wiley   +1 more source

FIG. 2 in Notes on distinguishing the cocoons and the juveniles of Hirudo medicinalis and Haemopis sanguisuga (Hirudinea)

open access: yes, 2000
FIG. 2. Top: typical new cocoons of Haemopis sanguisuga (above) and Hirudo medicinalis (below). Bottom: older, stained, cocoons of Hirudo medicinalis (left) and Haemopis sanguisuga (right).
Gaywood, Martin J.   +2 more
core   +1 more source

New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris

open access: yesAdvanced Materials Interfaces, Volume 12, Issue 20, October 27, 2025.
Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini   +7 more
wiley   +1 more source

Traditional Chinese Medicinal Herbs for Treating Post‐Ischemic Stroke Cognitive Impairment Insights From Frequency and Association Analysis

open access: yesBrain and Behavior, Volume 15, Issue 9, September 2025.
This analysis highlights key herbs and their interactions, suggesting significant implications for further research into their efficacy and safety for stroke rehabilitation. ABSTRACT Background This study analyzes medicinal herbs in Traditional Chinese Medicine (TCM) formulations for post‐ischemic stroke cognitive impairment, identifying key herbs ...
Yixia Li   +3 more
wiley   +1 more source

An Investigation into the Diversity of Leeches (Hirudinida) in the Baltic States

open access: yesDiversity
The Baltic states—Estonia, Latvia, and Lithuania—are situated on the eastern coast of the Baltic Sea between Russia and the Scandinavian countries. This region is characterized by diverse landscapes and numerous bodies of water, including lakes, peat ...
Jurgita Rutkauskaite-Suciliene   +2 more
doaj   +1 more source

Traditional Chinese Medicine Properties and Microcalorimetry: BioScience Evaluation

open access: yesMed Research, Volume 1, Issue 1, Page 103-121, June 2025.
ABSTRACT The properties theory of traditional Chinese medicine (TCM), characterized by cold, hot, warm, and cool four properties, is fundamental to its development, distinguishing it from natural, botanical, and chemical medicines. However, despite its significance, there is no unified theoretical definition, bioscientific characterization, or ...
Qiang Li   +9 more
wiley   +1 more source

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