Identification and characterization of hirudin-HN, a new thrombin inhibitor, from the salivary glands of Hirudo nipponia [PDF]
Transcriptome sequencing data (6.5 Gb) of the salivary glands of the haematophagous leech Hirudo nipponia was obtained by using the BGIseq-500 platform.
Boxing Cheng +6 more
doaj +2 more sources
Ingestive behaviour and physiology of the medicinal leech [PDF]
Ingestion lasts 25 min in Hirudo medicinalis and is characterized by pharyngeal peristalsis which fills the crop. This peristalsis has an initial rate of 2.4 Hz which decays smoothly to 1.2 Hz at termination of ingestion. During ingestion, the leech body
Dickinson, M. H. +3 more
core
Naragh Suburb, Center of Iran; A Natural Habitat of Hirudo medicinalis
Aims A very common species of leeches has been named as Hirudo medicinalis. Regarding to the application of leeches in medicine and their fast extinction, this study was performed in aquatic habitats of Kashan aimed to determine the distribution of ...
Dehghani R.1 PhD, +3 more
doaj
New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris
Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini +7 more
wiley +1 more source
Was previously discovered that in the leech Hirudo medicinalis, acetyl-l-carnitine (ALC) affects forms of non-associative learning, such as sensitization and dishabituation, due to nociceptive stimulation of the dorsal skin in the swim induction ...
Giovanna Traina
doaj +1 more source
This analysis highlights key herbs and their interactions, suggesting significant implications for further research into their efficacy and safety for stroke rehabilitation. ABSTRACT Background This study analyzes medicinal herbs in Traditional Chinese Medicine (TCM) formulations for post‐ischemic stroke cognitive impairment, identifying key herbs ...
Yixia Li +3 more
wiley +1 more source
Medicinal leeches extract at complex treatment of experimental acute myocardial infarction in rats
Creating of pharmacological forms based on the medicinal leech extract is a perspective decision of various clinical pathologies. To introduce a new drug into clinical practice is need to investigate its influence on the treatment effectivity at ...
G. I Nikonov +2 more
doaj
Traditional Chinese Medicine Properties and Microcalorimetry: BioScience Evaluation
ABSTRACT The properties theory of traditional Chinese medicine (TCM), characterized by cold, hot, warm, and cool four properties, is fundamental to its development, distinguishing it from natural, botanical, and chemical medicines. However, despite its significance, there is no unified theoretical definition, bioscientific characterization, or ...
Qiang Li +9 more
wiley +1 more source
Pharmacological Activities and Mechanisms of Hirudin and Its Derivatives - A Review
Hirudin, an acidic polypeptide secreted by the salivary glands of Hirudo medicinalis (also known as “Shuizhi” in traditional Chinese medicine), is the strongest natural specific inhibitor of thrombin found so far. Hirudin has been demonstrated to possess
Chen Junren +22 more
doaj +1 more source
Kinetic and thermodynamic analysis of leech-derived tryptase inhibitor interaction with bovine tryptase and bovine trypsin [PDF]
The interaction of leech-derived tryptase inhibitor (LDTI) with bovine liver capsule tryptase (BLCT) and bovine trypsin has been studied using both thermodynamic and kinetic approaches.
Auerswald E.A. +6 more
core +1 more source

