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Pharmacogenomics, 2009
Genetic polymorphisms for histamine-metabolizing enzymes are responsible for interindividual variation in histamine metabolism and are associated with diverse diseases. Initial reports on polymorphisms of histamine-related genes including those coding for the enzymes histidine decarboxylase (HDC), diamine oxidase (ABP1) and histamine N ...
García Martín, Elena +4 more
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Genetic polymorphisms for histamine-metabolizing enzymes are responsible for interindividual variation in histamine metabolism and are associated with diverse diseases. Initial reports on polymorphisms of histamine-related genes including those coding for the enzymes histidine decarboxylase (HDC), diamine oxidase (ABP1) and histamine N ...
García Martín, Elena +4 more
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Studies on histamine and histamine antagonists
Journal of Allergy, 1948Abstract 1.1. The results of some experiments on histamine and antihistaminic drugs in allergic patients were reported. 2.2. A histamine release from allergic skin reactions was shown. 3.3. A disturbed histamine metabolism was shown in allergic patients by an increase of blood histamine after histamine injection (histamine tolerance curve) and ...
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Toxicon, 2021
Histamine intoxications result when histamine-metabolizing enzymes are compromised or overwhelmed by dietary histamine in the human body. This can occur either due to metabolic enzyme deficiencies, such as in histamine intolerance to wines, aged cheese and other foods or from high concentrations of histamine following ingestion of decomposed fish.
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Histamine intoxications result when histamine-metabolizing enzymes are compromised or overwhelmed by dietary histamine in the human body. This can occur either due to metabolic enzyme deficiencies, such as in histamine intolerance to wines, aged cheese and other foods or from high concentrations of histamine following ingestion of decomposed fish.
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Histamine and the hypothalamus
Neuroscience, 1983The chemical tools that could be used to examine the function of histamine in the brain are considered together with the evidence linking histamine specifically with the hypothalamus. The distribution of histamine and the enzymes responsible for its synthesis and metabolism is consistent with there being both mast cells and histaminergic nerve ...
F. Roberts, C.R. Calcutt
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Scandinavian Journal of Gastroenterology, 1991
Histamine is formed by decarboxylation of the amino acid histidine and is found both in plants and in animals, including man. In man it has important biologic functions. To assess the physiologic role of histamine, however, it is necessary to have a reliable and convenient method to determine its concentration in biologic fluids and tissue.
B. Schulze Søgnen +3 more
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Histamine is formed by decarboxylation of the amino acid histidine and is found both in plants and in animals, including man. In man it has important biologic functions. To assess the physiologic role of histamine, however, it is necessary to have a reliable and convenient method to determine its concentration in biologic fluids and tissue.
B. Schulze Søgnen +3 more
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Histamine and Histamine Receptors in Allergic Dermatitis
2016In this chapter we will first introduce the pathophysiological process of several skin diseases including allergic dermatitis, a common skin disease, including chronic allergic contact dermatitis (CACD), and atopic dermatitis (AD). In CACD and AD patients, repeated skin exposure to antigens contributes to the development of chronic eczematous lesions ...
Masahiro Seike, Hiroshi Ohtsu
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Histamine and Methyl-Histamine
1995Histamine is widely distributed throughout all tissues although its main sites of synthesis and storage are the tissue mast cell and the blood basophil. Histamine is synthesized from histidine by a specific decarboxylase and stored in the secretory granules. On activation of the cells histamine is released by degranulation.
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Histamine, histamine receptors, and anti-histamines in the context of allergic responses
LymphoSign Journal, 2019Histamine is a bioactive amine which is considered a key player in the allergic response. Thus, histamine receptor blockers (antihistamines) play an important role in the treatment of a number atopic diseases such as allergic rhinitis, conjunctivitis, and acute and chronic forms of urticaria.
Amarilla B. Mandola +2 more
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Histamine in the nervous system.
Physiological Reviews, 2008Histamine is a transmitter in the nervous system and a signaling molecule in the gut, the skin, and the immune system. Histaminergic neurons in mammalian brain are located exclusively in the tuberomamillary nucleus of the posterior hypothalamus and send ...
H. Haas, O. Sergeeva, O. Selbach
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American Review of Respiratory Disease, 2015
In an effort to explain the large variation of airway reactivity to histamine in human subjects in vivo, we have examined the relationship between histamine responses in vivo and isoproterenol in vitro.
J. Cerrina +5 more
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In an effort to explain the large variation of airway reactivity to histamine in human subjects in vivo, we have examined the relationship between histamine responses in vivo and isoproterenol in vitro.
J. Cerrina +5 more
semanticscholar +1 more source