Results 151 to 160 of about 46,942 (270)

Understanding the clinical management of co‐occurring sleep‐related bruxism and obstructive sleep apnea in adults: A narrative and critical review

Journal of Prosthodontics, Volume 34, Issue S1, Page 46-61, April 2025.
Abstract Sleep‐related bruxism (SRB) is a motor oral behavior characterized by tooth grinding and jaw clenching activity, reported by 8%–12% of the adult general population and 3% of older individuals. The frequency of one of its biomarkers, rhythmic masticatory muscle activity (RMMA), remains elevated across ages.
Cibele Dal Fabbro, Thomas Bornhardt‐Suazo, Anaïs Landry Schönbeck, Micheline de Meyer, Gilles J. Lavigne   +4 more
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Pitolisant 40 mg for excessive daytime sleepiness in obstructive sleep apnea patients treated or not by CPAP: Randomised phase 3 study

Journal of Sleep Research, Volume 34, Issue 3, June 2025.
Summary Obstructive sleep apnea (OSA) syndrome commonly leads to excessive daytime sleepiness (EDS). Pitolisant, a selective histamine‐3 receptor antagonist, is efficacious at doses up to 20 mg once daily in OSA treated or not with continuous positive airway pressure (CPAP).
Yves Dauvilliers, Sonya Elizabeth Craig, Maria R. Bonsignore, Ferran Barbé, Johan Verbraecken, Jerryl Asin, Ognian Georgiev, Rumen Tiholov, Christian Caussé, Jeanne‐Marie Lecomte, Jean‐Charles Schwartz, Philippe Lehert, Winfried Randerath, Jean‐Louis Pépin, on behalf of the HAROSA III Study Group, Dejan Dokic, Hristo Metev, Iliev Kartev, Zdravka Karamyan, Ventsislav Nozharov, Daniel Petkov   +20 more
wiley   +1 more source

Histamine Antagonists to Temper the Cytokine Overproduction in Gastrointestinal Cells Infected by SARS-CoV-2

, 2020
Geurdes H, Koutsaroff I.
europepmc   +1 more source

MRI‐based surrogates of brain clearance in narcolepsy type 1

Journal of Sleep Research, EarlyView.
Summary Brain clearance involves the drainage of waste molecules from the brain, a process that is suggested to be amplified during sleep. Recently proposed MRI‐based methods attempt to approximate human brain clearance with surrogate measures. The current study aimed to explore whether two brain clearance surrogates are altered in narcolepsy.
Eva M. van Heese, Jari K. Gool, Gert Jan Lammers, Ysbrand D. van der Werf, Matthias J. P. van Osch, Rolf Fronczek, Lydiane Hirschler   +6 more
wiley   +1 more source

Bacterial Histamine as a Therapeutic Target for Abdominal Pain in Irritable Bowel Syndrome: A Literature Review. [PDF]

Cureus
Mohamed Siraj H, Usaid M, Shaikh S, Dalain M, Ansari Y, Zehra Naqvi S, Hossain R, Anum H, Andrews Ravi C, Pant N, Awasarikar M, Husain K, Anand Hanchate A, Sagam A, Balasubramanian A.   +14 more
europepmc   +1 more source

Dreaming of Better Treatments: Advances in Drug Development for Sleep Medicine and Chronotherapy

Journal of Sleep Research, EarlyView.
ABSTRACT Throughout history, the development of new sleep medicines has been driven by progress in our understanding of the mechanisms underlying sleep. Ancient civilisations used their understanding of the sedative nature of natural herbs and compounds to induce sleep.
Brooke A. Prakash, Ishani Shah, Guohao Ni, Sridhar Vasudevan, Aarti Jagannath, Russell G. Foster   +5 more
wiley   +1 more source

Intranasal Chlorpheniramine for Early Symptomatic Treatment of COVID-19 and the Impact on Long-COVID. [PDF]

Cureus
Ferrer G, Valerio-Pascua F, Alas-Pineda C, Gaitán-Zambrano K, Pavón-Varela DJ.   +4 more
europepmc   +1 more source

Clinical Characteristics and Outcomes of Patients With Rome IV Functional Dyspepsia Who Consume Opioids: A Real‐World Study

Neurogastroenterology &Motility, EarlyView.
Approximately one in three patients with Rome IV functional dyspepsia (FD) consume opioids and this is associated with older age, depression/anxiety, and chronic pain. Opioid cessation alongside a neuromodulator improved symptoms in 29% of cases, with a number needed to treat of 5.7, suggesting that this treatment strategy may be beneficial in FD ...
Mohsin F. Butt, Grace Isherwood, Tilly Lewis‐Lawson, Caterina Sbarigia, Christian Lambiase, Razan N. M. Aburumman, Arkadeep Dhali, Debbie Bush, Tim Card, Maura Corsetti   +9 more
wiley   +1 more source

iPSC-derived human sensory neurons reveal a subset of TRPV1 antagonists as anti-pruritic compounds. [PDF]

Sci Rep
Tay SH, Pang JKS, Ng W, Ng CY, Khong ZJ, Chong ZS, Soh BS, Ng SY.   +7 more
europepmc   +1 more source