LifeHistamine receptor antagonists, which can bind to specific histamine receptors on target cells, exhibit substantial therapeutic efficacy in managing a variety of histamine-mediated disorders.
Erwen Kou
exaly +4 more sources
The Impact of H1–H4 Receptor Antagonists on the Levels of Selected Oxidative Stress Markers in Liver and Muscle Tissue in an Animal Model of Colitis [PDF]
PharmaceuticalsBackground/Objectives: The global prevalence and incidence of inflammatory bowel diseases have risen in the past two decades. Among them, Crohn’s disease and ulcerative colitis are still challenging to treat due to vascular and proliferative alterations.
Bartosz Bogielski +16 more
doaj +2 more sources
RELEASE OF HISTAMINE BY H2-RECEPTOR ANTAGONISTS [PDF]
The Lancet, 1982 letter
Parkin, J. V. +4 more
openaire +5 more sources
The Roles of Cardiovascular H2-Histamine Receptors Under Normal and Pathophysiological Conditions
Frontiers in Pharmacology, 2021 This review addresses pharmacological, structural and functional relationships among H2-histamine receptors and H1-histamine receptors in the mammalian heart.
Joachim Neumann +4 more
doaj +1 more source
Suppression of wheal and flare in histamine test by the main H1 antihistamines commercialized in Brazil [PDF]
Anais Brasileiros de Dermatologia, 2018 : Background: Several dermatoses are mediated by histamine, such as urticaria, angioedema, and papular urticaria. There are no Brazilian studies comparing the potency of antihistamines.
Helena Maciel-Guerra +6 more
doaj +2 more sources
Prediction of Ventilator-Associated Pneumonia in Patients Undergoing Stress Ulcer Prophylaxis: A Longitudinal Descriptive Study in Iran [PDF]
Journal of Kerman University of Medical Sciences, 2020 Background: The purpose of this study was to investigate and predict ventilator-associated pneumonia (VAP) in the two groups of patients who received either proton pump inhibitors (Pantoprazole) or histamine H2 antagonist (Ranitidine).
Shahriar Nikpour +7 more
doaj +1 more source
Histamine H1 receptor antagonists selectively kill cisplatin-resistant human cancer cells
Scientific Reports, 2021 Cancer therapy is often hampered by the disease’s development of resistance to anticancer drugs. We previously showed that the autonomously upregulated product of fibroblast growth factor 13 gene (FGF13; also known as FGF homologous factor 2 (FHF2)) is ...
Nobuki Matsumoto +5 more
doaj +1 more source
Famotidine-induced reversal of meperidine-related serotonin syndrome: a case report [PDF]
Korean Journal of Anesthesiology, 2017 Serotonin syndrome is an unexpected fatal adverse event related to serotonergic medication. This case report is the first report describing the possible treatment effect of famotidine on serotonin syndrome.
Soohyun Joe +5 more
doaj +1 more source
The Quantum Nature of Drug-Receptor Interactions: Deuteration Changes Binding Affinities for Histamine Receptor Ligands. [PDF]
PLoS ONE, 2016 In this article we report a combined experimental and computational study concerning the effects of deuteration on the binding of histamine and two other histaminergic agonists to 3H-tiotidine-labeled histamine H2 receptor in neonatal rat astrocytes ...
Mojca Kržan +7 more
doaj +1 more source
ANTISECRETORY TREATMENT FOR PEDIATRIC GASTROESOPHAGEAL REFLUX DISEASE - A SYSTEMATIC REVIEW
Arquivos de Gastroenterologia, 2017 BACKGROUND: Proton pump inhibitors and histamine H2 receptor antagonists are two of the most commonly prescribed drug classes for pediatric gastroesophageal reflux disease, but their efficacy is controversial.
Ângelo Zambam de MATTOS +4 more
doaj +1 more source