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A DFT study of the chemical reactivity of cimetidine A, C and D in the gas, H2O, MeOH and EtOH solvents [PDF]

open access: yesJournal of the Serbian Chemical Society, 2017
% Fukui % DFT s KR nema In the present work, we have analyzed the chemical reactivity of cimetidine A, C and D in different solvents; through the evaluation of global and local DFT reactivity descriptors.
Mendoza Huizar Luis Humberto   +4 more
doaj   +1 more source

Formulation and Evaluation of Cimetidine as a Topical Preparation

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2007
Cimetidine is a H2 – receptor blocking drug, widely used for the treatment of stomach ulcer in addition to its immune response modifying activity. This study is carried out to formulate cimetidine in a stable topical preparation.The in vitro release of ...
Ali A Yas, Nidhal K. Marie
doaj   +1 more source

Comparative Study of Protective Effect of Cimetidine and Verapamil on Paracetamol-Induced Hepatotoxicity in Mice

open access: yesInternational Journal of Hepatology, 2020
Paracetamol, chemically known as acetaminophen, if taken in higher doses has hepatotoxic potential. Cimetidine by inhibiting the cytochromal enzymes and reducing the production of the toxic metabolite can reduce the hepatotoxic potential while Verapamil ...
Lubna Danish   +5 more
doaj   +1 more source

Cimetidine Does Not Inhibit 5-Aminolevulinic Acid Synthase or Heme Oxygenase Activity: Implications for Treatment of Acute Intermittent Porphyria and Erythropoietic Protoporphyria

open access: yesBiomolecules, 2023
Acute intermittent porphyria (AIP) is characterized by acute neurovisceral attacks that are precipitated by the induction of hepatic 5-aminolevulinic acid synthase 1 (ALAS1).
Makiko Yasuda   +5 more
doaj   +1 more source

Cimetidine hepatitis

open access: yesGastroenterology, 1979
This case of an adult with cimetidine-induced hepatitis is presented. An etiologic role for the drug was strongly suggested when the patient developed transient hepatic dysfunction after two reexposures to cimetidine, which reverted promptly on withdrawal of the drug.
J P, Villeneuve, H A, Warner
openaire   +4 more sources

Vitamin B12 Prevents Cimetidine-Induced Androgenic Failure and Damage to Sperm Quality in Rats

open access: yesFrontiers in Endocrinology, 2019
Cimetidine, used as an anti-ulcer and adjuvant treatment in cancer therapy, causes disorders in the male reproductive tract, including steroidogenesis. However, its effect on sperm quality and male fertility has been poorly addressed.
Flávia Luciana Beltrame   +6 more
doaj   +1 more source

Cimetidine: A Safe Treatment Option for Cutaneous Warts in Pediatric Heart Transplant Recipients

open access: yesMedical Sciences, 2018
Background and Objectives: Immunosuppressed individuals are at particularly increased risk for human papilloma virus-related infections. The primary objective of our study is to determine if there are any adverse effects associated with high-dose ...
Bibhuti B Das   +7 more
doaj   +1 more source

Acute tubulointerstitial nephritis associated with antineutrophil cytoplasmic antibody following cimetidine treatment: a case report

open access: yesBMC Nephrology, 2021
Background Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis usually induces rapidly progressive glomerulonephritis, including pauci-immune necrotizing crescentic glomerulonephritis.
Keita Morimoto   +7 more
doaj   +1 more source

Cimetidine inhibits salivary gland tumor cell adhesion to neural cells and induces apoptosis by blocking NCAM expression

open access: yesBMC Cancer, 2008
Background Cimetidine, a histamine type-2 receptor antagonist, has been reported to inhibit the growth of glandular tumors such as colorectal cancer, however the mechanism of action underlying this effect is unknown.
Sakashita Hideaki   +2 more
doaj   +1 more source

Chronic calcific periarthritis of the elbow treated by cimetidine administration: Five cases

open access: yesJournal of Orthopaedic Surgery, 2017
Calcific periarthritis or calcific tendinitis occurs most frequently in the shoulder and rarely in the elbow. Cimetidine was previously reported to be effective for chronic calcific periarthritis of the shoulder.
Hiroo Kimura   +6 more
doaj   +1 more source

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