Results 11 to 20 of about 15,425 (224)

Cimetidine Enhances Antigen-Specific IgE and Th2 Cytokine Production

Allergology International, 2011
Background: Treatment with anti-ulcer drugs has been shown to enhance IgE production against food antigens. However, little is known about the immunological effects of cimetidine, a histamine receptor type 2 (H2R) antagonist that is widely used as an ...
Ken Arae, Keisuke Oboki, Tatsukuni Ohno, Masako Hirata, Susumu Nakae, Haruhiko Taguchi, Hirohisa Saito, Toshiharu Nakajima   +7 more
doaj   +2 more sources

Cimetidine Pharmacodynamics and Pharmacokinetics in Healthy Subjects: A Comparison of Tablets and Suspension [PDF]

Canadian Journal of Gastroenterology, 1994
The objective of this study was to compare the effect of cimetidine 200 mg tablet with that of cimetidine suspension (200 mg/10 mL), a 20 mL suspension of 800 mg magnesium hydroxide and 912 mg aluminum hydroxide, and matching placebo on intragastric pH ...
ABR Thomson, P Kirdeikis, L Zuk, RE Samuels, P Zarevics   +4 more
doaj   +2 more sources

Formulation and Evaluation of Cimetidine as a Topical Preparation

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2007
Cimetidine is a H2 – receptor blocking drug, widely used for the treatment of stomach ulcer in addition to its immune response modifying activity. This study is carried out to formulate cimetidine in a stable topical preparation.The in vitro release of ...
Ali A Yas, Nidhal K. Marie
doaj   +3 more sources

Physiologically‐Based Pharmacokinetic Model‐Informed Labeling for Cariprazine Drug Interactions With CYP3A Inhibitors [PDF]

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 4, April 2026.
ABSTRACT Cariprazine is a potent D3‐preferring dopamine D3/D2 receptor partial agonist, a serotonin 5‐HT1A receptor partial agonist, and a serotonin 5‐HT2B receptor antagonist approved for the treatment of a variety of psychiatric disorders. A clinical study examining short‐term (4 days) drug–drug interactions (DDIs) between cariprazine and ...
Md Mahbubul Huq Riad, Patrick Marroum, Mohamad Shebley, Hao Xiong   +3 more
wiley   +2 more sources

Ameliorative effects of Brassica oleracea var. viridis ethanol extract and fractions on cimetidine-induced reproductive toxicity in male Wistar rats [PDF]

Frontiers in Veterinary Science
BackgroundMale infertility is a global health issue, with pharmaceutical agents such as cimetidine contributing significantly to gonadotoxicity through antiandrogenic and oxidative mechanisms.
Emmanuel Orire Ikuomola, Daniel Udofia Owu, Victor Otu Oka, Olufunke Onaadepo, Felix Nnaemeka Ugwu, Patrick Maduabuchi Aja   +5 more
doaj   +2 more sources

Effects of probenecid and cimetidine on the pharmacokinetics of nemonoxacin in healthy Chinese volunteers

Drug Design, Development and Therapy, 2016
Yi-fan Zhang,1 Xiao-jian Dai,1 Yong Yang,1 Xiao-yan Chen,1 Ting Wang,2 Yun-biao Tang,3 Cheng-yuan Tsai,4 Li-wen Chang,4 Yu-ting Chang,4 Da-fang Zhong1 1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of ...
Zhang YF, Dai XJ, Yang Y, Chen XY, Wang T, Tang YB, Tsai CY, Chang LW, Chang YT, Zhong DF   +9 more
doaj   +1 more source

Case Report: Oral Cimetidine Administration Causes Drug-Induced Immune Hemolytic Anemia by Eliciting the Production of Cimetidine-Dependent Antibodies and Drug-Independent Non-specific Antibodies

Frontiers in Medicine, 2021
Previously, it was reported that multiple patients had hemolytic anemia associated with cimetidine administration, while only one patient who had received intravenous cimetidine was serologically diagnosed with drug-induced immune hemolytic anemia (DIIHA)
Yuanjun Wu, Yong Wu, Yanli Ji, Yanhui Liu, Dongsheng Wu, Jiajie Liang, Ganping Guo, Baochan Chen   +7 more
doaj   +1 more source

Ameliorative Effect of Cimetidine and Silymarin on Acute Acetaminophen-induced Hepatotoxicity in Adult Albino Rats: An Experimental Comparative Study [PDF]

The Egyptian Journal of Forensic Sciences and Applied Toxicology, 2019
Acetaminophen is an analgesic and antipyretic drug, its overdose cause hepatotoxicity. The current antidote for acetaminophen hepatotoxicity is N-acetyl cysteine (NAC); however, NAC has been resulted in severe side effects as seizures, intracranial ...
Rabab F. Hindawy, Abdelmonem G. Madboly, Eslam S. Metwally, Atef Fouda, asmaa abdelaziz soliman   +4 more
doaj   +1 more source

Cimetidine for erythropoietic protoporphyria

, 2022
Background: Erythropoietic protoporphyria (EPP) is caused by deficiency of the enzyme converting protoporphyrin IX (PpIX) into heme resulting in accumulation of PpIX; leading to photosensitivity and liver toxicity.
Heerfordt, Ida M., Lerche, Catharina M., Wulf, Hans Christian   +2 more
core   +1 more source

Pengaruh Jus Buah Pepaya (Carica papaya L.) terhadap Profil Farmakokinetik Simetidin pada Tikus Putih (Rattus norvegicus)

Journal of Tropical Pharmacy and Chemistry, 2016
Drugs used with foods or drinks can affect the drug effects. This study aims to observe the effect of papaya juice (Carica papaya L.) to the pharmacokinetics profile of cimetidine in white rats. The animal were randomly in three group.
Siti Julaicha, Adam M. Ramadhan, Rolan Rusli   +2 more
doaj   +1 more source