Results 31 to 40 of about 15,425 (224)

Vitamin B12 Prevents Cimetidine-Induced Androgenic Failure and Damage to Sperm Quality in Rats

Frontiers in Endocrinology, 2019
Cimetidine, used as an anti-ulcer and adjuvant treatment in cancer therapy, causes disorders in the male reproductive tract, including steroidogenesis. However, its effect on sperm quality and male fertility has been poorly addressed.
Flávia Luciana Beltrame, Fabiane de Santi, Vanessa Vendramini, Regina Elizabeth Lourenço Cabral, Sandra Maria Miraglia, Paulo Sérgio Cerri, Estela Sasso-Cerri   +6 more
doaj   +1 more source

Cimetidine: A Safe Treatment Option for Cutaneous Warts in Pediatric Heart Transplant Recipients

Medical Sciences, 2018
Background and Objectives: Immunosuppressed individuals are at particularly increased risk for human papilloma virus-related infections. The primary objective of our study is to determine if there are any adverse effects associated with high-dose ...
Bibhuti B Das, Kristin Anton, Nelia Soares, Susan Riojas, Jodi Mcdermott, Leah Knox, Susan Daneman, Bao N Puente   +7 more
doaj   +1 more source

Chronic calcific periarthritis of the elbow treated by cimetidine administration: Five cases

Journal of Orthopaedic Surgery, 2017
Calcific periarthritis or calcific tendinitis occurs most frequently in the shoulder and rarely in the elbow. Cimetidine was previously reported to be effective for chronic calcific periarthritis of the shoulder.
Hiroo Kimura, Takuji Iwamoto, Satoshi Oki, Noboru Matsumura, Masaya Nakamura, Morio Matsumoto, Kazuki Sato   +6 more
doaj   +1 more source

Cimetidine inhibits salivary gland tumor cell adhesion to neural cells and induces apoptosis by blocking NCAM expression

BMC Cancer, 2008
Background Cimetidine, a histamine type-2 receptor antagonist, has been reported to inhibit the growth of glandular tumors such as colorectal cancer, however the mechanism of action underlying this effect is unknown.
Sakashita Hideaki, Kusama Kaoru, Fukuda Masakatsu   +2 more
doaj   +1 more source

Pharmacodynamic Modeling to Evaluate the Impact of Cimetidine, an OCT2 Inhibitor, on the Anticancer Effects of Cisplatin

Cells, 2022
Despite potent anticancer activity, the clinical utilization of cisplatin is limited due to nephrotoxicity. As Organic Cation Transporter 2 (OCT2) has been shown to be one of the key transporters involved in the uptake of cisplatin into renal proximal ...
Hardik Mody, Tanaya R. Vaidya, Lawrence J. Lesko, Sihem Ait-Oudhia   +3 more
doaj   +1 more source

Cimetidine

, 2018
37Conf
Dmitry Sharapa (4994636)
core   +1 more source

Curcuma longa normalized cimetidine‐induced pituitary‐testicular dysfunction: Relevance in nutraceutical therapy

Animal Models and Experimental Medicine, 2019
Background The increasing incidence of chemically induced infertility is both a social threat and a threat to the continuation of life itself. Treatment or management therapy is often expensive. This study investigated the effects of acetone extract of a
Ngozi Joy Onwuemene, Christian Eseigbe Imafidon, Abiodun Oladele Ayoka   +2 more
doaj   +1 more source

Cimetidine-Associated Thrombocytopenia

, 1983
A case of thrombocytopenia associated with cimetidine administration in a 65-year-old white female with recurrent adenocarcinoma is reported. Her platelet count fell from 273 000/mm3 to 35 000/mm3 after cimetidine therapy was started.
Joseph R. Schneider, Henry J. Mann, John B. Miller, John P. Delaney   +3 more
core   +1 more source

Interactions of Human- and Rat-Organic Anion Transporters With Pravastatin and Cimetidine

Journal of Pharmacological Sciences, 2004
We have elucidated the interactions of human and rat organic anion transporters (hOATs and rOATs) with pravastatin and cimetidine. Pravastatin inhibited hOAT1/rOAT1, hOAT2/rOAT2, hOAT3/rOAT3, and hOAT4. The mode of inhibition was noncompetitive for hOAT1
Suparat Khamdang, Michio Takeda, Minoru Shimoda, Rie Noshiro, Shinichi Narikawa, Xiu-Lin Huang, Atsushi Enomoto, Pawinee Piyachaturawat, Hitoshi Endou   +8 more
doaj   +1 more source

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source