Results 51 to 60 of about 12,244 (184)
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.ABSTRACT Nemtabrutinib is a Bruton's tyrosine kinase (BTK) inhibitor under clinical investigation in patients with hematologic malignancies, including chronic lymphocytic leukemia and small lymphocytic lymphoma (CLL/SLL). Nemtabrutinib plasma concentration data from 578 patients enrolled in phase 1 and 2 clinical studies, treated with doses from 5 to ...
Chiara C. Kemal +3 more
wiley +1 more source
Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 846-858, April 2026.Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic +4 more
wiley +1 more source
Recurrence of Acute Duodenal Ulcer
Canadian Journal of Gastroenterology, 1994 Nizatidine, 300 mg once nightly, was compared with cimetidine, 800 mg once nightly, for treatment of 212 adult out-patients with acute duodenal ulcers in an eight-week randomized, double-blind, multicentre trial.
RJ Bailey +8 more
doaj +1 more source
INNOVATION IN GASTROENTEROLOGICAL MANAGEMENT: THE CASE OF CIMETIDINE
Prometheus, 1984 Gastroenterological medicine has, in recent decades, experienced two major innovations, viz. fibre optic endoscopy (a diagnostic technology) and cimetidine, an innovation in ulcer therapy.
D.P. Doessel, J.J. Sams
doaj +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1095-1104, April 2026.Cannabidiol (CBD) is one of the most abundant bioactive cannabinoids. Research has demonstrated CBD’s ability to inhibit metabolic enzymes like cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT), potentially leading to drug interactions. However, clinical knowledge gaps remain, particularly with regard to drugs that are more commonly taken by ...
Pablo Salcedo +11 more
wiley +1 more source
Increased Glomerular Filtration Rate in Early Stage of Balkan Endemic Nephropathy
Medicina, 2019 Background: A previous study indicated that Balkan endemic nephropathy (BEN) patients in the early stage of the disease had significantly higher creatinine clearance (Ccr) than healthy persons.
Ljubica Djukanović +4 more
doaj +1 more source
Photodiagnosis and Photodynamic TherapyBackground: Erythropoietic protoporphyria (EPP) patients are deficient in the ferrochelatase enzyme which converts protoporphyrin IX (PpIX) into heme, causing PpIX to accumulate in mature erythrocytes and skin.
Hans Christian Wulf +2 more
doaj +1 more source
Penile warts: an update on their evaluation and management
Drugs in Context, 2018 Background: Penile warts are the most common sexually transmitted disease in males. Clinicians should be familiar with the proper evaluation and management of this common condition.
Alexander KC Leung +3 more
doaj +1 more source
Effect of cimetidine on cyclophosphamide-induced liver toxicity in albino rats
Asian Journal of Medical Sciences, 2018 Background: The clinical use of cyclophosphamide (CP) has been characterised by liver toxicity. Aims and Objectives: This research assessed the effect of cimetidine against CP-induced liver toxicity in a rat model. Material and Methods: Forty eight
Elias Adikwu , Bonsome Bokolo
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Journal of Research in Medical Sciences, 2002 Introduction. Cimetidine and quinacrine have protective effect on gastroduodenal lesions. In this study we compared efficacy of cimetidine and quinacrine for prevention of stress and aspirin Induced Peptic Ulcer. Methods.
L BORJIAN, A.R RAHMANI
doaj