Results 61 to 70 of about 15,425 (224)
Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 846-858, April 2026.Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic +4 more
wiley +1 more source
Effect of Cimetidine on Oral Digoxin Absorption
, 1990 Cimetidine is a commonly prescribed histamine2-receptor antagonist used in the treatment of gastric acid-related disorders. Cimetidine can interact with a number of drugs, including theophylline, benzodiazepine sedative hypnotics, warfarin, and ...
Paul H. Krissman +3 more
core +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1095-1104, April 2026.Cannabidiol (CBD) is one of the most abundant bioactive cannabinoids. Research has demonstrated CBD’s ability to inhibit metabolic enzymes like cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT), potentially leading to drug interactions. However, clinical knowledge gaps remain, particularly with regard to drugs that are more commonly taken by ...
Pablo Salcedo +11 more
wiley +1 more source
Depression Associated with Cimetidine
, 1981 Over the past three years we have seen twelve patients who have become depressed while taking cimetidine. Clinically the depression is similar to that seen in a Primary Affective Disorder. Two representative cases are presented.
R.F. Billings, V.M. Rakoff, S.W. Tang
core +1 more source
BiomedicinesHistamine modulates immunity by binding to histamine receptor 2 (H2R). Cimetidine, an H2R antagonist that inhibits gastric acid secretion and treats gastrointestinal ulcers, interferes with histamine-mediated immunomodulation and may have anticancer ...
Feng-Chi Kuo +5 more
doaj +1 more source
Increased Glomerular Filtration Rate in Early Stage of Balkan Endemic Nephropathy
Medicina, 2019 Background: A previous study indicated that Balkan endemic nephropathy (BEN) patients in the early stage of the disease had significantly higher creatinine clearance (Ccr) than healthy persons.
Ljubica Djukanović +4 more
doaj +1 more source
Health Science Reports, Volume 9, Issue 4, April 2026.ABSTRACT Background and Aim Stress‐related mucosal bleeding among critically ill patients in intensive care unit (ICU) contributes substantially to morbidity and mortality. Despite growing concerns globally over inappropriate stress ulcer prophylaxis (SUP) use, limited data exist from Ethiopia, particularly in ICU settings.
Samuel Agegnew Wondm +11 more
wiley +1 more source
Cimetidine secretion by rabbit renal tubules in vitro
, 1981 Cimetidine, a drug in widespread use in the treatment of peptic ulcer disease, is eliminated primarily via urinary excretion. We examined cimetidine transport by rabbit proximal straight tubules perfused in vitro. [3H]Cimetidine in the bath was actively
P. Myers, T. D. McKinney, K. V. Speeg
core +1 more source
Penile warts: an update on their evaluation and management
Drugs in Context, 2018 Background: Penile warts are the most common sexually transmitted disease in males. Clinicians should be familiar with the proper evaluation and management of this common condition.
Alexander KC Leung +3 more
doaj +1 more source
Effect of cimetidine on cyclophosphamide-induced liver toxicity in albino rats
Asian Journal of Medical Sciences, 2018 Background: The clinical use of cyclophosphamide (CP) has been characterised by liver toxicity. Aims and Objectives: This research assessed the effect of cimetidine against CP-induced liver toxicity in a rat model. Material and Methods: Forty eight
Elias Adikwu , Bonsome Bokolo
doaj +1 more source