Results 21 to 30 of about 356,503 (221)
Perioperative nonspecific histamine release: a new classification by aetiological mechanisms and evaluation of their clinical relevance [PDF]
, 1993 As a consequence of the performance of a randomized controlled clinical trial on perioperative histamine release and cardiovascular and respiratory disturbances, several types of increases in plasma histamine had to be distinguished instead of only two ...
Lorenz, Wilfried +9 more
core +1 more source
Histamine and Delirium: Current Opinion
Frontiers in Pharmacology, 2019 Delirium is a very common, but refractory clinical state, notably present in intensive care and in the growing aging community. It is characterized by fluctuating disturbances in a number of key behavioral features, namely cognition, mood, attention ...
Paul L. Chazot +3 more
doaj +1 more source
Highly potent, selective acylguanidine-type histamine H2 receptor agonists: synthesis and structure-activity relationships [PDF]
, 2008 Potent and selective histamine H2 receptor (H2R) agonists are valuable pharmacological tools and might be of therapeutic value as drugs, for example in the treatment of severe congestive heart failure.
Kraus, Anja
core +1 more source
Histamine H2-receptor antagonists for urticaria
Cochrane Database of Systematic Reviews, 2012 Urticaria is a common skin disease characterised by itching weals or hives, which can occur almost anywhere on the body. There are a number of different subtypes and a range of available treatment options. There is lack of agreement on the efficacy of H2-receptor antagonists used in the treatment of urticaria.To assess the safety and effectiveness of ...
Fedorowicz, Z. +2 more
openaire +4 more sources
Journal of Pharmacological Sciences, 2003 Although it is well known that histamine induces gastric mucosal lesions in laboratory animals, the fundamental mechanisms remain unclear. In order to further analyze the vascular mechanisms underlying histamine-induced lesions, a new model was developed
Kikuko Amagase, Susumu Okabe
doaj +1 more source
Novel chalcone-based fluorescent human histamine H 3 receptor ligands as pharmacological tools [PDF]
, 2012 Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif.
Miriam Tomasch +7 more
core +1 more source
The Histamine H4 Receptor: From Orphan to the Clinic
Frontiers in Pharmacology, 2015 The histamine H4 receptor (H4R) was first noted as a sequence in genomic databases that had features of a G-protein coupled receptor. This putative receptor was found to bind histamine consistent with its homology to other histamine receptors and thus ...
Robin L. Thurmond
doaj +1 more source
Determination of histamine in human plasma: the European external quality control study 1988 [PDF]
, 1990 There is an increasing interest in measuring human plasma histamine levels in various clinical conditions. A variety of 'old' and newly developed techniques are applied to meet this demand.
Lorenz, Wilfried +7 more
core +1 more source
Frontiers in Immunology, 2022 BackgroundSystemic allergic reaction is characterized by vasodilation and vascular leakage, which causes a rapid, precipitous and sustained decrease in arterial blood pressure with a concomitant decrease of cardiac output.
Shangze Gao +9 more
doaj +1 more source
The Effect of H2 Receptor Antagonist in Acid Inhibition and Its Clinical Efficacy
The Korean Journal of Gastroenterology, 2017 The first histamine H2 receptor antagonists (H2RAs) were developed in the early 1970s. They played a dominant role in treating peptic ulcer disease and gastroesophageal reflux disease (GERD).
Young Kwang Shim, Nayoung Kim
doaj +1 more source