Results 11 to 20 of about 9,091 (225)

Molecular Encapsulation of Histamine H2-Receptor Antagonists by Cucurbit[7]Uril: An Experimental and Computational Study

open access: yesMolecules, 2016
The histamine H2-receptor antagonists cimetidine, famotidine and nizatidine are individually encapsulated by macrocyclic cucurbit[7]uril (CB[7]), with binding affinities of 6.57 (±0.19) × 103 M−1, 1.30 (±0.27) × 104 M−1 and 1.05 (±0.33) × 105 M−1 ...
Hang Yin   +5 more
doaj   +2 more sources

Use of histamine H2 receptor antagonists and outcomes in patients with heart failure: a nationwide population-based cohort study

open access: yesClinical Epidemiology, 2018
Kasper Adelborg,1 Jens Sundbøll,1,2 Morten Schmidt,1,3 Hans Erik Bøtker,2 Noel S Weiss,4 Lars Pedersen,1 Henrik Toft Sørensen1 1Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; 2Department of ...
Adelborg K   +6 more
doaj   +1 more source

Collagenous gastritis: A cause of anemia and gastric nodularity in the pediatric population. [PDF]

open access: yesJPGN Rep
Abstract We present a case series of seven pediatric patients with collagenous gastritis (CG) with the aim of contributing data to existing literature about this rare disease to assist in the understanding and management of these patients. Gross nodularity seen on esophagogastroduodenoscopy and increased subepithelial collagen on biopsy were noted in ...
Emiliani M, Heintz D, Izaguirre M.
europepmc   +2 more sources

Prophylaxis of anaphylactoid reactions to a polypeptidal plasma substitute by H1- plus H2-receptor antagonists: synopsis of three randomized controlled trials [PDF]

open access: yes, 1982
To demonstrate the efficacy of a premedication with H1- + H2-receptor antagonists against histamine-release responses in anaesthesia and surgery 3 randomized controlled trials were conducted in patients, volunteers and experimental animals (dogs ...
Lorenz, Wilfried   +5 more
core   +1 more source

Votucalis, a Novel Centrally Sparing Histamine-Binding Protein, Attenuates Histaminergic Itch and Neuropathic Pain in Mice

open access: yesFrontiers in Pharmacology, 2022
Votucalis is a biologically active protein in tick (R. appendiculatus) saliva, which specifically binds histamine with high affinity and, therefore, has the potential to inhibit the host’s immunological responses at the feeding site. We hypothesized that
Ibrahim Alrashdi   +12 more
doaj   +1 more source

Predictors of Response to Oral Medications and Low-Histamine Diet in Patients with Chronic Urticaria

open access: yesJournal of Immunology Research, 2022
Background. Chronic urticaria (CU) is comprised of diverse phenotypes, and thus, a shift towards a precision medical approach is warranted in its management. Methods. This study enrolled 78 patients with CU.
Hui-Ling Chiang   +4 more
doaj   +1 more source

Histamine and Delirium: Current Opinion

open access: yesFrontiers in Pharmacology, 2019
Delirium is a very common, but refractory clinical state, notably present in intensive care and in the growing aging community. It is characterized by fluctuating disturbances in a number of key behavioral features, namely cognition, mood, attention ...
Paul L. Chazot   +3 more
doaj   +1 more source

Histamine H2-receptor antagonists for urticaria

open access: yesCochrane Database of Systematic Reviews, 2012
Urticaria is a common skin disease characterised by itching weals or hives, which can occur almost anywhere on the body. There are a number of different subtypes and a range of available treatment options. There is lack of agreement on the efficacy of H2-receptor antagonists used in the treatment of urticaria.To assess the safety and effectiveness of ...
Fedorowicz, Z.   +2 more
openaire   +4 more sources

On the Mechanisms Underlying Histamine Induction of Gastric Mucosal Lesions in Rats With Partial Gastric Vascular Occlusion

open access: yesJournal of Pharmacological Sciences, 2003
Although it is well known that histamine induces gastric mucosal lesions in laboratory animals, the fundamental mechanisms remain unclear. In order to further analyze the vascular mechanisms underlying histamine-induced lesions, a new model was developed
Kikuko Amagase, Susumu Okabe
doaj   +1 more source

The Histamine H4 Receptor: From Orphan to the Clinic

open access: yesFrontiers in Pharmacology, 2015
The histamine H4 receptor (H4R) was first noted as a sequence in genomic databases that had features of a G-protein coupled receptor. This putative receptor was found to bind histamine consistent with its homology to other histamine receptors and thus ...
Robin L. Thurmond
doaj   +1 more source

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