Results 21 to 30 of about 10,782,665 (139)

Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat [PDF]

, 2004
Background: In rat, deafferentation of one labyrinth (unilateral labyrinthectomy) results in a characteristic syndrome of ocular and motor postural disorders (e.g., barrel rotation, circling behavior, and spontaneous nystagmus). Behavioral recovery (e.g.,
Panula, Pertti, Lozada, Adrian F., Kaj Karlstedt, Karlstedt, Kaj, Aarnisalo, Antti A., Stark, Holger, Adrian F Lozada, Pertti Panula, Antti A Aarnisalo, Holger Stark, Karlstedt Kaj, Stark Holger, Panula Pertti, Aarnisalo Antti A, Lozada Adrian F   +14 more
core   +1 more source

Preventive Effects of Non-sedating and Sedating Histamine H₁ Receptor Antagonists Premedication for Subcutaneous Daratumumab-Associated Infusion-Related Reactions: A Prospective Observational Study

Biological and Pharmaceutical Bulletin
The optimal choice between sedating histamine H1 antagonists (sAHs) and non-sedating histamine H1 antagonists (nsAHs) for preventing infusion-related reactions (IRRs) during daratumumab subcutaneous (DARA-SC) therapy remains unclear. Here, we aimed to compare the efficacy and safety of nsAH and sAH as premedication for DARA-SC therapy.
Mayu Yakumaru-Suzukawa, Tohru Aomori, Norifumi Suzuki, Koichi Ohata, Maiko Abumiya, Yukiyoshi Fujita, Tomoe Yoshizawa, Kaori Matsumoto, Akira Kudo, Naoya Suehiro, Shiori Hishida-Sadaka, Haruka Igarashi, Chinami Inoue, Tomoko Yamazaki, Junichiro Wakatsuki, Hiroomi Sakurai, Serika Banno-Matsuoka, Yayoi Fukushi, Hirotoshi Iihara, Masafumi Kikuchi, Hitoshi Kawazoe, Hisakazu Ohtani   +21 more
openaire   +2 more sources

Histamine receptors in GtoPdb v.2021.3 [PDF]

, 2021
Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 173]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80]. The human and rat
Levi, Roberto, Leurs, Rob, Cowart, Marlon, Hill, Stephen J., Young, J. Michael, Gutzmer, Ralf, Seifert, Roland, Ganellin, C. Robin, Shankley, Nigel P., Timmerman, Henk, Haas, Helmut L., Stark, Holger, Panula, Pertti, Schunack, Walter, Chazot, Paul, Fukui, Hiroyuki, Liu, Steve, Schwartz, Jean-Charles, Hills, Rebecca, Thurmond, Robin, Steve Liu, Jean-Charles Schwartz, Holger Stark, Nigel P. Shankley, Robin Thurmond, Paul Chazot, Stephen J. Hill, J. Michael Young, Marlon Cowart, Rebecca Hills, C. Robin Ganellin, Rob Leurs, Roberto Levi, Hiroyuki Fukui, Roland Seifert, Walter Schunack, Henk Timmerman, Pertti Panula, Helmut L. Haas, Ralf Gutzmer   +39 more
core   +1 more source

Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractile activity via H1 and H2 receptors [PDF]

, 2019
The mechanisms underlying bladder contractile disorders such as overactive bladder are not fully understood, and there is limited understanding of the receptor systems modulating spontaneous bladder contractions.
Stromberga, Zane, Chess-Williams, Russ, Moro, Christian; id_orcid   +2 more
core   +1 more source

Biosensors for Food Safety and Adulteration Monitoring: Applications, Smart Packaging Integration, and Pathways to Intelligent, Field‐Deployable Detection Systems

Food Safety and Health, EarlyView.
Biosensors enable rapid, sensitive, and portable detection of pathogens, contaminants, allergens, and food adulteration. Integration with smart packaging, smartphones, IoT, and machine learning supports real‐time monitoring and intelligent decision‐making, whereas microfluidics, biodegradable materials, explainable AI, and blockchain offer pathways ...
Mohima Akther Any, Abid Hassan Arnab, Liza Akter, Yusuf Chowdhury, Md. Hassan Bin Nabi, Md Abu Rayhan, Nazmul Islam, Wahidu Zzaman   +7 more
wiley   +1 more source

Neurological Adverse Effects Associated With Commonly Used H1‐Antihistamines: A Narrative Review of Age‐Stratified Risk Profiles in Paediatric and Geriatric Populations

Medicine Advances, EarlyView.
This narrative review examines the neurological adverse effects associated with commonly used H1‐antihistamines, focusing on how blood–brain barrier (BBB) penetration and patient age influence central nervous system (CNS) toxicity. The major finding is that first‐generation antihistamines, because of higher CNS penetration, are associated with ...
Syeda Samia Fatima, Zahabia Adnan, Rabia Nizam, Marium Fawad, Zainab Mehmood, Areeba Asif, Ali Aamir   +6 more
wiley   +1 more source

Effect of histamine H1 and H2 receptor antagonists on histamine-induced macrophage LOX-1 mRNA expression.

, 2014
Monocyte-derived macrophages were incubated in the presence of 10 µM histamine and the indicated concentrations of the histamine H1 and H2 receptor antagonists (pyrilamine and ranitidine, respectively) for 4 h and analyzed for LOX-1 mRNA expression.
Petri T. Kovanen (188189), Mervi Alanne-Kinnunen (633861), Katariina Öörni (221897), Jani Lappalainen (245191)   +3 more
core   +1 more source

Histamine receptors in GtoPdb v.2023.1 [PDF]

, 2023
Histamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Histamine Receptors [80, 174]) are activated by the endogenous ligand histamine. Marked species differences exist between histamine receptor orthologues [80]. The human and rat
Hill, Stephen J., Young, J. Michael, Steve Liu, Jean-Charles Schwartz, Shankley, Nigel P., Haas, Helmut L., Holger Stark, Nigel P. Shankley, Robin Thurmond, Paul Chazot, Stephen J. Hill, Fukui, Hiroyuki, Hills, Rebecca, J. Michael Young, Levi, Roberto, Leurs, Rob, Marlon Cowart, Rebecca Hills, Cowart, Marlon, Gutzmer, Ralf, C. Robin Ganellin, Seifert, Roland, Ganellin, C. Robin, Rob Leurs, Roberto Levi, Timmerman, Henk, Stark, Holger, Panula, Pertti, Hiroyuki Fukui, Schunack, Walter, Chazot, Paul, Roland Seifert, Liu, Steve, Schwartz, Jean-Charles, Walter Schunack, Henk Timmerman, Pertti Panula, Helmut L. Haas, Thurmond, Robin, Ralf Gutzmer   +39 more
core   +1 more source

Management of chronic urticaria: Current status and future prospect

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chronic urticaria is driven by mast cell activation through autoimmune, inflammatory, and neuroimmune pathways. A structured approach combining diagnosis, patient‐reported outcomes, stepwise therapy, treatment optimization, monitoring and emerging targeted agents may improve disease control and enable more personalized management.
Andaç Salman, Mona Al‐Ahmad, Maryam Al‐Nesf, Chia‐Yu Chu, Luis Felipe Ensina, Ana M. Gimenez‐Arnau, Margarida Gonçalo, Clive Grattan, Michihiro Hide, Pavel Kolkhir, Martin Metz, Iman Nasr, Romi Saini, Simon Francis Thomsen, Torsten Zuberbier, Emek Kocaturk   +15 more
wiley   +1 more source

Predictors of Torsades de Pointes in rabbit ventricles perfused with sedating and nonsedating histamine H₁-receptor antagonists

, 2000
Several nonsedating histamine H1-receptor antagonists are associated with torsades de pointes ventricular tachycardia. The objectives of this study were to: (i) compare electrocardiographic, monophasic action potential, and arrhythmogenic effects of ...
Cahill, SA, Gross, GJ, McCartney, DG, Jeremy D Gilbert, Anton Lukas, Sean A Cahill, Lukas, A, Douglas G McCartney, Gilbert, JD, Gil J Gross   +9 more
core   +1 more source