Results 31 to 40 of about 10,782,665 (139)

Treatment of Canine Atopic Dermatitis: Updated Guidelines From the International Committee on Allergic Diseases of Animals (ICADA)

Veterinary Dermatology, EarlyView.
ABSTRACT Background Canine atopic dermatitis (cAD) is a genetically, aetiologically, immunologically and clinically complex disease requiring both individualised immediate and long‐term management. Objectives These updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA) aim to substantially revise previous ...
Ralf S. Mueller, Frane Banovic, Emmanuel Bensignor, Domenico Santoro, Tim Nuttall   +4 more
wiley   +1 more source

Intact Cell Binding for In Vitro Prediction of Sedative and Non-sedative Histamine H1–Receptor Antagonists Based on Receptor Internalization

, 2008
We evaluated changes in the binding properties of sedative and non-sedative histamine H1–receptor antagonists induced by internalization of H1 receptors in intact human U373 MG astrocytoma cells.
Hiroshi Komazaki, Shigeru Hishinuma, Yusuke Kobayashi, Yuko Sato, Masaki Saito   +4 more
core   +1 more source

Characterization of the Lysophosphatidic Acid Receptor 5 Antagonist RLPA‐76 as a Novel Analgesic in Male Rats and Mice

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Clinically used analgesics such as gabapentinoids and opioids have limited efficacy and adverse effects like abuse liability, and there is a dire need for novel analgesics with improved safety profiles. Since lysophosphatidic acid can induce neuropathic pain in rodents, LPA receptor antagonists have been investigated as potential analgesics ...
Kristen L. Woodhouse, Maowei Wang, Sai Ganesh Balaji Venkata Anupindi, Olatunbosun Adeoke, Dehui Zhang, Yanan Zhang, Jun‐Xu Li   +6 more
wiley   +1 more source

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis

International Journal of Dermatology, Volume 65, Issue 12, Page 2497-2508, December 2026.
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller, Helmut Beltraminelli, Wolf‐Henning Boehncke, Maximilian Böhm, Antonio Cozzio, Peter Häusermann, Ahmad Jalili, Antonios G. A. Kolios, Claudia Lang, Eva Loos, Christoph Schlapbach, Curdin Conrad   +11 more
wiley   +1 more source

Therapies used to control symptoms related to the release of mast-cell mediators in ISM patients grouped according to the sBT slope (<0.15 vs. ≥0.15) after 48 months of follow-up.

, 2013
Results are expressed as number of cases and percentage between brackets.No statistically significant differences (p >0.05) were found between groups.*Scheduled disodium cromolyn plus scheduled non-sedating or sedating H1 and/or H2 antihistamines, and/or
Alberto Orfao (108164), Elisa Fernández-Núñez (470588), José Mario Morgado (470583), Carlos Eduardo Pedreira (470586), Cristina Teodosio (143750), Iván Álvarez-Twose (470584), Ricardo Moreno-Borque (470589), Andrés García-Montero (470590), Paula Sánchez-López (470587), María Jara-Acevedo (309208), Almudena Matito (470582), Luis Escribano (470591), Laura Sánchez-Muñoz (470585)   +12 more
core   +1 more source

Cutaneous‐only hypersensitivity reaction presumed due to intravenous administration of atracurium in a dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary There are limited case reports of hypersensitivity reactions to neuromuscular blocking agents (NMBAs) in veterinary species, and none describe cutaneous‐only signs. This case report describes a Grade 1 cutaneous‐only hypersensitivity reaction to atracurium in a 7‐year‐old dog undergoing general anaesthesia for cataract surgery with bilateral ...
Kar Yee Phoon, Rob Ward
wiley   +1 more source

Fexofenadine hydrochloride in the treatment of allergic disease: a review

Journal of Asthma and Allergy, 2008
David Axelrod1, Leonard Bielory2Division of Allergy, Immunology and Rheumatology, UMDNJ-New Jersey Medical School, 1Department of Medicine, 2Departments of Medicine, Pediatrics, Ophthalmology and Visual Sciences, Newark, New Jersey, USAAbstract ...
David Axelrod, Leonard Bielory
doaj  

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, Volume 67, Issue 10, Page 5075-5125, October 2026.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Effects of Trazodone on Testicular Morphology, Sperm Parameters and Contractility of the Distal Cauda Epididymal Duct in Rats

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Trazodone is an antidepressant approved for the treatment of major depressive disorder and is associated with a low incidence of sexual dysfunction. However, its effects on male reproductive health are not yet fully understood. Therefore, this study aimed to evaluate the effects of repeated trazodone administration on reproductive parameters ...
Maria Santana da Silva, Vitória Barros Marques, Fernanda Karoline Oliveira da Silva, Maele Oliveira de Sena, Yanka do Vale Carvalho, Bruna da Silva Figueiredo, Luana Talinne da Costa Gomes, Samia Ellen Alves Fernandes, Edherlayne Bezerra dos Santos Silva, Jackson Nazareno Gomes de Lima, Anna Karynna Alves de Alencar Rocha, Expedito Silva do Nascimento Junior, Elaine Cristina Gavioli, Edilson Dantas da Silva Junior   +13 more
wiley   +1 more source

O neuropeptídio Y (NPY) na medula espinhal medeia o efeito hiponociceptivo da ativação de receptores H1 histaminérgicos na articulação do joelho de ratos [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013.A histamina é encontrada no líquido sinovial de indivíduos saudáveis e pacientes com diversos tipos ...
Silva, Eduardo Souza
core