Results 131 to 140 of about 57,473 (326)

Effects of Olopatadine Hydrochloride, a Histamine H1 Receptor Antagonist, on Histamine-Induced Skin Responses [PDF]

, 2010
Effects of olopatadine hydrochloride, a histamine H1 receptor antagonist, on histamine-induced skin responses were evaluated in 10 healthy subjects in comparison with placebo, fexofenadine hydrochloride, and bepotastine besilate.
Dainichi, Teruki, Hamada, Takahiro, Hashimoto, Takashi, Ishii, Norito, Karashima, Tadashi, Nakama, Takekuni, Yasumoto, Shinichiro   +6 more
core   +3 more sources

Histamine suppresses T helper 17 responses mediated by transforming growth factor-β1 in murine chronic allergic contact dermatitis

AIMS Allergy and Immunology, 2018
Allergic skin diseases are caused by the introduction of antigen into the skin. Repeated application of antigens prompts the development of atopic dermatitis (AD) and chronic allergic contact dermatitis (CACD).
Masahiro Seike
doaj   +1 more source

A remark on H1 martingales [PDF]

arXiv, 2018
The space of H1 martingales is interesting because of its duality with the space of BMO martingales. It is straightforward to show that every H1 martingale is a uniformly integrable martingale. However, the converse is not true. That is to say, some uniformly integrable martingales are not H1 martingales.
arxiv  

miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. [PDF]

, 2019
ObjectiveOnset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped-MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small ...
Aaen, Gregory, Barcellos, Lisa F, Belman, Anita, Benson, Leslie, Caillier, Stacy, Candee, Meghan S, Casper, T Charles, Chitnis, Tanuja, Gorman, Mark, Graves, Jennifer S, Greenberg, Benjamin M, Harris, Yolanda, Hart, Janace, Kahn, Ilana, Krupp, Lauren, Lotze, Timothy, Mar, Soe, Ness, Jayne, Quach, Diana, Quach, Hong, Rhead, Brooke, Rodriguez, Moses, Rose, John, Rubin, Jennifer, Schaefer, Catherine, Schreiner, Teri, Shao, Xiaorong, Tillema, Jan M, US Network of Pediatric MS Centers, Waldman, Amy T, Waubant, Emmanuelle, Weinstock-Guttman, Bianca   +31 more
core   +2 more sources

Identification of Amino Acid Residues Responsible for Agonist-Induced Down-Regulation of Histamine H1 Receptors

Journal of Pharmacological Sciences, 2004
The histamine H1 receptor (H1R) level is dynamically regulated in vivo under various physiological and pathological conditions. The H1R regulation may consist of various processes, and this study focused on the process of receptor trafficking, that is ...
Shuhei Horio, Maki Ogawa, Nozomi Kawakami, Katsumi Fujimoto, Hiroyuki Fukui   +4 more
doaj  

H1 antihistamines in allergic rhinitis: The molecular pathways of interleukin and toll - like receptor systems

Journal of Health Sciences, 2016
The complex interaction between inflammatory mediators in allergic rhinitis (AR) is determined by the role of genetic polymorphisms, including interleukin (IL) and toll-like receptor (TLR) genes.
Jonny Karunia Fajar
doaj   +1 more source

The role of atrial natriuretic peptide to attenuate inflammation in a mouse skin wound and individually perfused rat mesenteric microvessels. [PDF]

, 2016
We tested the hypothesis that the anti-inflammatory actions of atrial natriuretic peptide (ANP) result from the modulation of leukocyte adhesion to inflamed endothelium and not solely ANP ligation of endothelial receptors to stabilize endothelial barrier
Adamson, Roger H, Clark, Joyce F, Curry, Fitz-Roy E, Jiang, Yanyan, Kim, Min-Ho, Simon, Scott I   +5 more
core   +2 more sources

Blocking Histamine H1 Improves Learning and Mnemonic Dysfunction in Mice With Social Isolation Plus Repeated Methamphetamine Injection

Journal of Pharmacological Sciences, 2008
The aim of this study was to investigate the effects of histamine H1 and H3 antagonists on learning and mnemonic dysfunction in mice. Two H1 antagonists, pyrilamine and clozapine, and the prototypic H3 antagonist thioperamide were used to study the role ...
Feiyong Jia, Jalal Izadi Mobarakeh, Hongmei Dai, Motohisa Kato, Ajing Xu, Tomohiro Okuda, Eiko Sakurai, Nobuyuki Okamura, Kazuhiro Takahashi, Kazuhiko Yanai   +9 more
doaj  

Inverse Agonistic Activity of Antihistamines and Suppression of Histamine H1 Receptor Gene Expression

Journal of Pharmacological Sciences, 2012
Histamine H1 receptor (H1R) expression influences the severity of allergy symptoms. We examined the effect of inverse agonists on H1R gene expression. Two inverse agonists (carebastine and mepyramine), but not the neutral antagonist oxatomide, decreased ...
Hiroyuki Mizuguchi, Shohei Ono, Masashi Hattori, Hiroyuki Fukui   +3 more
doaj  

Steroid Receptors and Vertebrate Evolution [PDF]

arXiv, 2019
Considering that life on earth evolved about 3.7 billion years ago, vertebrates are young, appearing in the fossil record during the Cambrian explosion about 542 to 515 million years ago. Results from sequence analyses of genomes from bacteria, yeast, plants, invertebrates and vertebrates indicate that receptors for adrenal steroids (aldosterone ...
arxiv