Results 11 to 20 of about 26,595 (267)

Cryo-EM structure of the human histamine H1 receptor/Gq complex. [PDF]

open access: goldNat Commun, 2021
Xia R   +7 more
europepmc   +3 more sources

Histamine promotes angiogenesis through a histamine H1 receptor-PKC-VEGF-mediated pathway in human endothelial cells

open access: yesJournal of Pharmacological Sciences, 2023
Histamine is a well-known inflammatory mediator, but how histamine induces angiogenesis remains poorly understood. In the present study, we demonstrated a dose-dependent dynamic tube formation in the human endothelial cell line EA.hy926 in the presence ...
Omer Faruk Hatipoglu   +8 more
doaj   +1 more source

Delineating the role of histamine-1- and -4-receptors in a mouse model of Th2-dependent antigen-specific skin inflammation. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Histamine drives pruritus in allergic skin diseases which clinically constitutes a most disruptive symptom. Skin pathology in allergic skin diseases is crucially influenced by different T-helper subsets. However, the contribution of different
Subhashree Mahapatra   +10 more
doaj   +1 more source

Intact Cell Binding for In Vitro Prediction of Sedative and Non-sedative Histamine H1–Receptor Antagonists Based on Receptor Internalization

open access: yesJournal of Pharmacological Sciences, 2008
We evaluated changes in the binding properties of sedative and non-sedative histamine H1–receptor antagonists induced by internalization of H1 receptors in intact human U373 MG astrocytoma cells.
Shigeru Hishinuma   +4 more
doaj   +1 more source

Resolvin D1 and Aspirin-Triggered Resolvin D1 Regulate Histamine-stimulated Conjunctival Goblet Cell Secretion [PDF]

open access: yes, 2014
Resolution of inflammation is an active process mediated by pro-resolution lipid mediators. Since resolvin (Rv) D1 is produced in the cornea, pro-resolution mediators could be effective in regulating inflammatory responses to histamine in allergic ...
Carozza, Richard B.   +7 more
core   +1 more source

Interaction of Central Glutamatergic and Histaminergic Systems on Food Intake Regulation in Layer Chickens [PDF]

open access: yesArchives of Razi Institute, 2021
This study purposed to discover the connection between the central glutamatergic and histaminergic systems on feeding behavior in layer chickens. In the first experiment, chicks obtained intracerebroventricular (ICV) injections of saline (control ...
M Mobarhan Fard   +3 more
doaj   +1 more source

Histamine Excites Rat Superior Vestibular Nuclear Neurons via Postsynaptic H1 and H2 Receptors in vitro

open access: yesNeurosignals, 2012
The superior vestibular nucleus (SVN), which holds a key position in vestibulo-ocular reflexes and nystagmus, receives direct hypothalamic histaminergic innervations.
Qian-Xing Zhuang   +4 more
doaj   +1 more source

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