Results 31 to 40 of about 26,595 (267)

Histamine H1 Receptor Down-Regulation Mediated by M3 Muscarinic Acetylcholine Receptor Subtype

Journal of Pharmacological Sciences, 2004
Heterologous down-regulation of histamine H1 receptor (H1R) mediated by muscarinic acetylcholine receptor subtype was investigated using five kinds of Chinese hamster ovary (CHO) cells stably co-expressing the human H1R and one of the five (M1 –M5 ...
Katsuhiro Miyoshi, Nozomi Kawakami, Yousuke Wakayama, Norimasa Izumi, Shuhei Horio, Hiroyuki Fukui   +5 more
doaj   +1 more source

Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms [PDF]

, 2018
Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces acute proinflammatory responses, but it also induces delayed systemic immunosuppressive effects ...
FitzGerald, Garret A., Kaplan, Mark H., Ocana, Jesus A., Pawelzik, Sven-Christian, Romer, Eric, Sahu, Ravi, Travers, Jeffrey B.   +6 more
core   +1 more source

Histamine and H1-histamine receptors faster venous circulation [PDF]

Journal of Cellular and Molecular Medicine, 2011
The study has analysed the action of histamine in the rabbit venous system and evaluated its potential role in contraction during increased venous pressure. We have found that a great variety exists in histamine sensitivity and H(1) -histamine receptor expression in various types of rabbit veins.
Galajda, Zoltan, Balla, Jozsef, Szentmiklosi, A Jozsef, Biro, Tamas, Czifra, Gabriella, Dobrosi, Nora, Cseppento, Agnes, Patonay, Lajos, Roszer, Tamas, Balla, Gyorgy, Popescu, Laurenciu M, Lekli, Istvan, Tosaki, Arpad   +12 more
openaire   +2 more sources

Typical and Atypical Antipsychotic Drugs Increase Extracellular Histamine Levels in the Rat Medial Prefrontal Cortex: Contribution of Histamine H1 Receptor Blockade

Frontiers in Psychiatry, 2012
Atypical antipsychotics such as clozapine and olanzapine have been shown to enhance histamine turnover and this effect has been hypothesized to contribute to their improved therapeutic profile compared to typical antipsychotics.
Kjell A Svensson
doaj   +1 more source

PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity [PDF]

, 2014
Transient receptor potential canonical 6 (TRPC6) is a cation selective, DAG-regulated, Ca2+-permeable channel activated by the agonists of Gq-protein-coupled heptahelical receptors.
Chen, Xingjuan, Egly, Christian, Hughes, Thomas E., Li, Wennan, Obukhov, Alexander G., Quinn, Anne Marie, Riley, Ashley M., Tewson, Paul   +7 more
core   +2 more sources

Homologous and Heterologous Phosphorylations of Human Histamine H1 Receptor in Intact Cells

Journal of Pharmacological Sciences, 2004
Homologous and heterologous phosphorylations of histamine H1 receptor (H1R) in intact cells were investigated using Chinese hamster ovary cells stably co-expressing c-myctagged human histamine H1 and muscarinic M3 receptors. Increase in histamine-induced
Katsuhiro Miyoshi, Nozomi Kawakami, Shuhei Horio, Hiroyuki Fukui   +3 more
doaj   +1 more source

Anti-Allergic Cromones Inhibit Histamine and Eicosanoid Release from Activated Human and Murine Mast Cells by Releasing Annexin A1 [PDF]

, 2013
PMCID: PMC3601088This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Ahluwalia, A Mulla, AB Kay, Ajantha Sinniah, AM Lucas, Bernhard Ryffel, C Bandeira-Melo, C Dahl, CD John, CF Schwender, CF Schwender, CP Sung, CP Sung, DS Thomson, E Solito, E Solito, E Wells, EB Cook, Egle Solito, F D'Acquisto, FL Pearce, FN Gavins, FS Ng, G Folkerts, G Galatowicz, J Raud, JD Croxtall, JP Tarayre, JP Tarayre, JP Tarayre, JS Cox, JS Cox, JS Cox, JS Cox, K Kuriyama, L Jenkins, L Wang, M Corbel, M Perretti, M Shichijo, MK Church, NJ Goulding, PJ Barnes, R Sagi-Eisenberg, RH Grace, RJ Rintala, RM Viscardi, Rod J. Flower, RP Hayhoe, S Mattoli, S Murphy, S Pieretti, S Yazid, S Yazid, Samia Yazid, SH Lee, SH Peers, SI Wasserman, SilvaJR Lapa e, SK Bansal, SM Oliani, T Du, T Oka, T Radeau, TC Theoharides, TC Theoharides, TW Evans, Virginia Calder, WM Abraham, WM Abraham, Y Okayama, Y Yang, Y Zuo, YW Chung   +73 more
core   +2 more sources

Ameliorative Effect of a Hippocampal Metabotropic Glutamate– Receptor Agonist on Histamine H1 Receptor Antagonist–Induced Memory Deficit in Rats

Journal of Pharmacological Sciences, 2010
This study was performed to investigate the ameliorative effects of metabotropic glutamate (mGlu)-receptor agonists on histamine H1 receptor antagonist–induced spatial memory deficit and the decrease in hippocampal theta activity in rats. Intraperitoneal
Takayoshi Masuoka, Azusa Mikami, Chiaki Kamei   +2 more
doaj   +1 more source

The Histamine H4 Receptor: From Orphan to the Clinic

Frontiers in Pharmacology, 2015
The histamine H4 receptor (H4R) was first noted as a sequence in genomic databases that had features of a G-protein coupled receptor. This putative receptor was found to bind histamine consistent with its homology to other histamine receptors and thus ...
Robin L. Thurmond
doaj   +1 more source

Combination of H1 and H2 Histamine Receptor Antagonists: Current Knowledge and Perspectives of a Classic Treatment Strategy

Life
Histamine receptor antagonists, which can bind to specific histamine receptors on target cells, exhibit substantial therapeutic efficacy in managing a variety of histamine-mediated disorders.
Erwen Kou, Xiaobei Zhang, Baiping Dong, Bo Wang, Yuanjie Zhu   +4 more
doaj   +1 more source