Results 31 to 40 of about 27,660 (289)
Direct imaging of lateral movements of AMPA receptors inside synapses [PDF]
EMBO J 22, 18 (15/09/2003) 4656-65, 2007 Trafficking of AMPA receptors in and out of synapses is crucial for synaptic plasticity. Previous studies have focused on the role of endo/exocytosis processes or that of lateral diffusion of extra-synaptic receptors. We have now directly imaged AMPAR movements inside and outside synapses of live neurons using single-molecule fluorescence microscopy ...
arxiv +1 more source
The Journal of Poultry Science, 2007 To implicate histamine and its receptors in feed intake and nutrient transport, White Leghorn cockerels of the same age and body weight were grouped randomly into six groups.
Abdul Nasir +2 more
doaj +1 more source
Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat [PDF]
, 2004 Background: In rat, deafferentation of one labyrinth (unilateral labyrinthectomy) results in a characteristic syndrome of ocular and motor postural disorders (e.g., barrel rotation, circling behavior, and spontaneous nystagmus). Behavioral recovery (e.g.,
Aarnisalo, Antti A. +4 more
core +2 more sources
Solubilization and Characterization of Histamine H1 receptors in brain. [PDF]
Journal of Biological Chemistry, 1982 [3H]Doxepin, a tricyclic antidepressant, binds with high affinity to guinea pig brain membranes with a drug specificity indicating an association with H1 histamine receptors. The [3H]doxepin binding site has been solubilized, with digitonin being the only detergent able to maintain specific binding after solubilization.
Solomon H. Snyder, L. Toll
openaire +2 more sources
Journal of Pharmacological Sciences, 2023 Histamine is a well-known inflammatory mediator, but how histamine induces angiogenesis remains poorly understood. In the present study, we demonstrated a dose-dependent dynamic tube formation in the human endothelial cell line EA.hy926 in the presence ...
Omer Faruk Hatipoglu +8 more
doaj
Large number of receptors may reduce cellular response time variation [PDF]
Physical biology 10 (3), 035008, 2013, 2012 Cells often have tens of thousands of receptors, even though only a few activated receptors can trigger full cellular responses. Reasons for the overabundance of receptors remain unclear. We suggest that, in certain conditions, the large number of receptors results in a competition among receptors to be the first to activate the cell.
arxiv +1 more source
Histamine H1-receptors modulate somatostatin receptors coupled to the inhibition of adenylyl cyclase in the rat frontoparietal cortex [PDF]
, 1997 Since exogenous histamine has been previously shown to increase the somatostatin (SS) receptor-effector system in the rat frontoparietal cortex and both histamine H1-receptor agonists and SS modulate higher nervous activity and have anticonvulsive ...
Arilla Ferreiro, Eduardo +2 more
core +3 more sources
The Histamine H4 Receptor: From Orphan to the Clinic
Frontiers in Pharmacology, 2015 The histamine H4 receptor (H4R) was first noted as a sequence in genomic databases that had features of a G-protein coupled receptor. This putative receptor was found to bind histamine consistent with its homology to other histamine receptors and thus ...
Robin L. Thurmond
doaj +1 more source
Algebraic study of receptor-ligand systems: a dose-response analysis [PDF]
arXiv, 2022 The study of a receptor-ligand system generally relies on the analysis of its dose-response (or concentration-effect) curve, which quantifies the relation between ligand concentration and the biological effect (or cellular response) induced when binding its specific cell surface receptor.
arxiv
Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms [PDF]
, 2012 Although large cholangiocytes exert their functions by activation of cyclic adenosine 3',5'-monophosphate (cAMP), Ca(2+)-dependent signaling regulates the function of small cholangiocytes. Histamine interacts with four receptors, H1-H4HRs.
Fanyin Meng +15 more
core +1 more source