Results 71 to 80 of about 27,660 (289)
Effects of Inhaled Brevetoxins in Allergic Airways: Toxin–Allergen Interactions and Pharmacologic Intervention [PDF]
, 2005 During a Florida red tide, brevetoxins produced by the dinoflagellate Karenia brevis become aerosolized and cause airway symptoms in humans, especially in those with pre-existing airway disease (e.g., asthma).
Andrea J. Bourdelais +7 more
core +2 more sources
Structure of the human histamine H1 receptor complex with doxepin [PDF]
Nature, 2011 The biogenic amine histamine is an important pharmacological mediator involved in pathophysiological processes such as allergies and inflammations. Histamine H(1) receptor (H(1)R) antagonists are very effective drugs alleviating the symptoms of allergic reactions.
Hirokazu Tsujimoto +14 more
openaire +2 more sources
Early Origins of Asthma and Allergies: Clues From Studies in China
Clinical &Experimental Allergy, EarlyView.The environment we live in harbours both risk and protective factors for asthma and allergies. This is particularly relevant in China, where unique environmental and cultural factors shape disease development. The interplay between these environmental factors, airway immunity, and gut microbiome shapes the susceptibility to asthma and allergies ...
Yike Wang +5 more
wiley +1 more source
Journal of Pharmacological Sciences, 2012 We examined the regulatory mechanisms of the affinity of Gq protein-coupled histamine H1-receptors for histamine after histamine pretreatment in intact human U373 MG astrocytoma cells.
Shigeru Hishinuma +3 more
doaj
Effect of histamine on the electric activities of cerebellar Purkinje cell [PDF]
arXiv, 1999 The effect of histamine (HA) on the electric activities of Purkinje cell (PC) is studied on the cerebellum slice. We find that: (1) HA's main effect on PC is excitative (72.9%); there are also a small amount of PC showing inhibitive (10.2%) or no (16.9%) response to HA.
arxiv
The Effects of Histamine H3 Receptors on Contractile Responses on Rat Gastric Fundus [PDF]
, 2006 The aim of this study is to determine the effects of histamine receptors on the gastrointestinal system smooth muscle contractions and the role of histamine H3 receptors on these effects.
Aşkın Hekimoğlu, Ramazan Çiçek
core
Polymorphisms of High-Affinity IgE Receptor and Histamine-Related Genes in Patients with ASA-Induced Urticaria/Angioedema [PDF]
, 2005 The pathogenic mechanism of ASA-induced urticaria/angioedema (AIU) is still poorly understood, but it has been known that histamine releasing by cutaneous mast cell activation is considered to be an important role. Considering the importance of histamine
Altman +30 more
core +3 more sources
Clinical Endocrinology, EarlyView.ABSTRACT Objective Managing gastrointestinal symptoms in patients with phaeochromocytoma and paraganglioma (PPGL) is challenging due to the risk of catecholaminergic crisis with many commonly prescribed medications, especially in functional tumours.
Monica Majumder +5 more
wiley +1 more source
Stem Cell Reports, 2019 Summary: The neurological recovery following traumatic brain injury (TBI) is limited, largely due to a deficiency in neurogenesis. The present study explores the effects of histamine H3 receptor (H3R) antagonism on TBI and mechanisms related to ...
Rujia Liao +11 more
doaj
Prospects of using Antagonist Histamine H2-Receptor (Cimetidinum) as Adjuvant for Melanoma Biotherapy Treatment [PDF]
International Journal of Immunopathology, Allergology, Infectology
2010, #4: P. 42-51, 2011 Improvement of anti-tumor biotherapy effectiveness by modification of immune response with histamine H2 receptor Cimetidinum (CM) was studied using the experimental murine model of B16 F10 melanoma in vivo. It is shown that skin melanoma biotherapy by antitumor whole-cell GM-CSF-producing vaccine with the addition of CM (in dose of 25 mg/kg, daily for ...
arxiv