Antacid preparations in the modern treatment of acid-base disorders
Медицинский совет, 2014 Until the middle of the XX century, a large group of drugs called antacids played the key role in the treatment of acid-related diseases. Antacids have long been used to relieve heartburn and pain in the upper gastrointestinal tract.
S. A. Babanov, E. B. Grischenko
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Proton-pump inhibitor use is associated with a broad spectrum of neurological adverse events including impaired hearing, vision, and memory. [PDF]
, 2019 Proton-pump inhibitors, PPIs, are considered effective therapy for stomach acid suppression due to their irreversible inhibition of the hydrogen/potassium pump in the gastric parietal cells. They are widely prescribed and are considered safe for over-the-
Abagyan, Ruben +4 more
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NF-kB overexpression and decreased immunoexpression of AR in the muscular layer is related to structural damages and apoptosis in cimetidine-treated rat vas deferens [PDF]
, 2013 Background: Cimetidine, histamine H-2 receptors antagonist, has caused adverse effects on the male hormones and reproductive tract due to its antiandrogenic effect.
Beltrame, Flavia L. +5 more
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Праці Наукового товариства імені Шевченка. Медичні науки, 2019 Professor of Lviv National Medical University (formerly known as Jan Kazimierz Lemberg University), Ukraine, Leon Popielski was the fi rst to recognize that histamine stimulated gastric acid secretion 100 years ago, at 1916.
Oksana Zayachkivska +2 more
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Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models. [PDF]
, 2016 Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes
Ahmed, Mohamed +5 more
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Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]
, 2012 Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
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Novelty in BiomedicineBackground: Histamine H2 antagonists (H2RAs) are hypothesized to inhibit suppressor T-lymphocyte function, with preliminary evidence from randomized trials suggesting potential prolongation of survival in patients with operable and inoperable gastric and
Farahnaz Zhian Zarangan +3 more
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Involvement of the histaminergic system in the resuscitating effect of centrally acting leptin in haemorrhagic shock in rats [PDF]
, 2016 Leptin, acting centrally as a neuromodulator, induces the activation of the sympathetic nervous system, which may lead to a pressor action in normotensive animals.
Altinbas, B. +7 more
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Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum [PDF]
, 1976 The root and stem decoctions of Sinomenium acutum Rehd. et Wils. (formerly Sinomenium diversifolius Diels, one type of Fang-chi (Chinese)) have been used as a folk remedy for neuralgia and rheumatoid arthritis in many areas of the Far East.
Yamasaki, Hidemasa
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HISTAMINE H2‐ANTAGONISTS MODIFY GASTRIC EMPTYING IN THE RAT
British Journal of Pharmacology, 1982 Giulio Bertaccini, C. Scarpignato
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