Results 81 to 90 of about 3,102 (198)

4-Hydroxypiperidines and Their Flexible 3-(Amino)propyloxy Analogues as Non-Imidazole Histamine H3 Receptor Antagonist: Further Structure–Activity Relationship Exploration and In Vitro and In Vivo Pharmacological Evaluation [PDF]

, 2018
Beata Olszewska, Anna Stasiak, Daniel A. McNaught-Flores, W. A. Fogel, Rob Leurs, Krzysztof Walczyński   +5 more
openalex   +1 more source

Determination of Histamine H3-Receptor Antagonist Conessine in Wistar Rat Plasma by a Rapid and Sensitive RP-UFLC Method: Application to a Pharmacokinetic Study [PDF]

, 2020
Nilesh Sudhakar Ambhore, Rama Satyanarayana Raju Kalidhindi, Shubhashri Mohire, Karthik Yamjala, Shashank Mulukutla, Vishakantha Murthy, Mahesh Thondawada, Elango Kannan   +7 more
openalex   +1 more source

Influence of the Novel Histamine H3 Receptor Antagonist/Inverse Agonist M39 on Gastroprotection and PGE2 Production Induced by (R)-Alpha-Methylhistamine in C57BL/6 Mice [PDF]

, 2019
Salim M. A. Bastaki, Naheed Amir, Małgorzata Więcek, Katarzyna Kieć‐Kononowicz, Bassem Sadek   +4 more
openalex   +1 more source

Pharmacological Properties of ABT-239 [4-(2-{2-[(2 R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and Selective Histamine H3 Receptor Antagonist with Drug-Like Properties

, 2005
Timothy A. Esbenshade, Gerard B. Fox, Kathleen M. Krueger, Thomas R. Miller, Chae Hee Kang, Lynne Denny, David G. Witte, Betty Yao, Liping Pan, Jill M. Wetter, Kennan C. Marsh, Youssef L. Bennani, Marlon Cowart, James P. Sullivan, Arthur A. Hancock   +14 more
openalex   +1 more source

A new and potent histamine H3 antagonist, clobenpropit (VUF-9153) and electrically-induced convulsions.

, 1994
Hiroyuki Yokoyama, Kenji Onodera, Kazuie Iinuma, Takehiko Watanabe   +3 more
openalex   +1 more source

LC–MS–MS Method for the Analysis of New Non-Imidazole Histamine H3 Receptor Antagonist 1-[3-(4-tert-Butylphenoxy)propyl]piperidine in Rat Serum—Application to Pharmacokinetic Studies [PDF]

, 2011
Małgorzata Szafarz, Joanna Szymura‐Oleksiak, Dorota Łażewska, Katarzyna Kieć‐Kononowicz   +3 more
openalex   +1 more source

Simultaneous inhibition of cholinesterase and antagonism of histamine H3 receptors alleviates cognitive deficits and mitigates apoptosis in scopolamine-induced amnesia in mice

Frontiers in Behavioral Neuroscience
IntroductionAlzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory deficits. Mounting evidence highlights the role of cholinergic and histaminergic neurotransmissions in the pathophysiology of ...
Wajd Ebdah, Wajd Ebdah, Shilu Deepa Thomas, Shilu Deepa Thomas, Nermin Eissa, Petrilla Jayaprakash, Petrilla Jayaprakash, Dorota Łażewska, Katarzyna Kieć-Kononowicz, Bassem Sadek, Bassem Sadek   +10 more
doaj   +1 more source

2025 ACVIM Forum Research Abstract Program

Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
wiley   +1 more source

Two Novel and Selective Nonimidazole Histamine H3 Receptor Antagonists A-304121 and A-317920: I. In Vitro Pharmacological Effects

, 2003
Timothy A. Esbenshade, Kathleen M. Krueger, Thomas R. Miller, Chae Hee Kang, Lynne Denny, David G. Witte, Betty Yao, Gerard B. Fox, Ramin Faghih, Youssef L. Bennani, Michael Williams, Arthur A. Hancock   +11 more
openalex   +1 more source

Binding Characteristics of a Histamine H3-Receptor Antagonist, [3H]S-Methylthioperamide: Comparison with [3H](R)α-Methylhistamine Binding to Rat Tissues

, 1994
Kazuhiko Yanai, Jong Hoon Ryu, Naruhiko Sakai, Toshihiro Takahashi, Ren Iwata, Tatsuo Ido, Kazuki Murakami, Takehiko Watanabe   +7 more
openalex   +1 more source