Results 261 to 270 of about 2,435,179 (382)

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

Epilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher, Dorothée Kasteleijn‐Nolst Trenité   +1 more
wiley   +1 more source

Enigmatic Histamine Receptor H₄ for Potential Treatment of Multiple Inflammatory, Autoimmune, and Related Diseases. [PDF]

Life (Basel), 2020
Mehta P, Miszta P, Rzodkiewicz P, Michalak O, Krzeczyński P, Filipek S.   +5 more
europepmc   +1 more source

Wakefulness is governed by GABA and histamine co-transmission [PDF]

, 2015
Brickley, SG, Franks, NP, Houston, CM, Ma, Y, Parker, S, Uygun, DS, Vyssotski, AL, Wisden, W, Yu, X, Yustos, Y, Zecharia, AY, Zhang, Z, Zhiwen, Y   +12 more
core   +1 more source

Equine botulism

Equine Veterinary Journal, EarlyView.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik, Robert Whitlock, Amy Johnson   +2 more
wiley   +1 more source

Blockade of histamine receptor H1 augments immune checkpoint therapy by enhancing MHC-I expression in pancreatic cancer cells. [PDF]

J Exp Clin Cancer Res
Zhong P, Nakata K, Oyama K, Higashijima N, Sagara A, Date S, Luo H, Hayashi M, Kubo A, Wu C, He S, Yamamoto T, Koikawa K, Iwamoto C, Abe T, Ikenaga N, Ohuchida K, Morisaki T, Oda Y, Kuba K, Nakamura M.   +20 more
europepmc   +1 more source

Effects of histamine and various histamine receptor antagonists on gene expression profiles of macrophages during compressive strain. [PDF]

J Orofac Orthop, 2022
Schröder A, Petring C, Damanaki A, Jantsch J, Proff P, Kirschneck C.   +5 more
europepmc   +1 more source

Biochemical analysis of specific histamine HI and H2 receptors on lymphocytes [PDF]

, 1981
ME Osband, EB Cohen, B. R. Miller, YJ Shen, L Cohen, L Flescher, Brown Ae, RP McCaffrey   +7 more
openalex   +1 more source

Sustained postexercise vasodilatation and histamine receptor activation following small muscle‐mass exercise in humans

Experimental Physiology, 2013
Zachary Barrett-O’Keefe, R. Kaplon, J. Halliwill   +2 more
semanticscholar   +1 more source

Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley   +1 more source

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

The FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source