Results 291 to 300 of about 126,927 (355)

Distinct Metabolomic Alterations Are Associated With Physical Function, Weight Loss, and Muscle Mass in Men With Cancer

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Treatments for cancer cachexia, defined as involuntary weight and muscle mass loss leading to significant functional impairment, remain unavailable partly due to insufficient improvement of clinically meaningful outcomes in current trials.
Lindsey J. Anderson   +9 more
wiley   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo   +11 more
wiley   +1 more source

Bed bug preferences for host odor or aggregation odor are differentially modulated by physiological state in various odorscapes

open access: yesPest Management Science, Volume 82, Issue 2, Page 1426-1436, February 2026.
The bed bug olfactory system is highly tuned to two odor sources with dedicated odor information‐processing pathways that are modulated by the satiety–hunger state. Understanding the dynamic nature of switching odor preferences at different phases of blood digestion will contribute to the development of lures with host kairomones and aggregation ...
Ayako Wada‐Katsumata   +4 more
wiley   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles   +3 more
wiley   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun   +16 more
wiley   +1 more source

Machine Learning Integration Framework Constructs a Lactylation‐Associated Gene Signature to Improve Prognosis in Bladder Cancer

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Bladder cancer remains a significant challenge in oncology owing to its high recurrence rates and limited treatment options, particularly in cases of resistance to standard therapies. Aims Our study aimed to pinpoint a lactylation‐associated gene signature capable of predicting prognosis and providing important theoretical support ...
Jingsong Wang   +8 more
wiley   +1 more source

Acanthospermum hispidum and Its Metabolite Stigmasterol Modulates Anti‐Inflammatory Antagonism of COX‐1 and TGF‐β

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
This study evaluates the anti‐inflammatory effect of Acanthospermum hispidum (AH) leaves and confirms its traditional use on diseases linked to inflammation. AH ethanol extract presents a dose‐dependent increase in anti‐inflammatory activity on the different times examined (T30 – T150). Also, stigmasterol present in AH shows potent antagonist influence
Onome Mary Adeboye   +6 more
wiley   +1 more source

Uni-hemispheric cortical astrocyte-specific histamine-1-receptor (H1R) conditional knockout (cKO) changes wake and REM dynamics with minimal impact to other sleep/wake features.

open access: green
Charlotte R. Taylor (22360068)   +6 more
openalex   +1 more source

Delayed Onset Unilateral Tongue Edema From ACE Inhibitor‐Induced Angioedema

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
An 84‐year‐old Japanese woman with unilateral tongue edema. ABSTRACT Recognize that angioedema induced by ACE inhibitors can present in atypical forms and may occur years after initiating therapy.
Mizuki Seki   +4 more
wiley   +1 more source

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