Results 91 to 100 of about 53,829 (294)

Histamine and activation of histamine receptors as drivers of early inflammation and gut function in pigs

, 2023
Early life adversity has been established as a major risk factor for the development of inflammatory disease as well as increased mortality in humans. In swine production, weaning is a necessary practice, but is also the most stressful life event that a ...
Thelen, Kyan
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Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

BMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang, Lu Han, He‐Qing Cai, Xin‐Yu Xue, Yi‐Fei Song, Wu‐Lin Xin, Ying‐Ze Wang, Peng Liu, Juan Liu   +8 more
wiley   +1 more source

Molecular Pharmacology of the Four Histamine Receptors

, 2010
Histamine and its receptors have been (and are still today) very fruitful topics for pharmacological and medicinal chemistry studies. In this chapter we review the various selective ligands that are available for the four different histamine receptors ...
Bongers, G, De Esch, I.J., Thurmond, Robin L., Leurs, R.   +3 more
core   +2 more sources

Effects of methimepip and JNJ-5207852 in Wistar rats exposed to an open-field with and without object and in Balb/c mice exposed to a radial-arm maze

, 2012
The role of the histamine H3 receptor (H3R) in anxiety is controversial, due to limitations in drug selectivity and limited validity of behavioral tests used in previous studies. In the present report, we describe two experiments.
Paul L. Chazot, Lethbridge, Natasha L., Ruan van Rensburg, Chazot, Paul L., Rushdie M. A. Abuhamdah, Abdel Ennaceur, Abuhamdah, Rushdie M., Natasha L. Lethbridge, van Rensburg, Ruan, Ennaceur, Abdelkader   +9 more
core   +1 more source

Histamine receptors and cancer pharmacology [PDF]

, 2010
Considerable evidence has been collected indicating that histamine can modulate proliferation of different normal and malignant cells. High histamine biosynthesis and content together with histamine receptors have been reported in different human ...
Elena S. Rivera, Vanina A. Medina, Rivera, Elena S., Medina, Vanina Araceli   +3 more
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Histamine receptors mediating vascular responses in brain [PDF]

, 1981
Several facts suggest that histamine may influence the function of cerebral blood vessels. 1) Histamine has important vascular effects in non-neural organs; 2) Cerebral microvessels and arteries contain receptors for histamine; 3) Enzyme systems in brain
Gross, Paul Munn
core   +1 more source

From Inflammatory Bowel Disease to Cancer: Gut Microbiota–Immune Microenvironment Crosstalk and Natural Product‐Based Therapeutic Opportunities

Cancer Nexus, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD), primarily Crohn's disease and ulcerative colitis, is a chronic relapsing inflammatory disorder of the gastrointestinal tract and an important risk factor for IBD‐associated cancer. Increasing evidence suggests that gut microbiota dysbiosis, epithelial barrier dysfunction, and immune microenvironment remodeling
Xue Zhang, Chongchong Gao, Rui Jiang, Zijian Wu, Jian Bai   +4 more
wiley   +1 more source

O neuropeptídio Y (NPY) na medula espinhal medeia o efeito hiponociceptivo da ativação de receptores H1 histaminérgicos na articulação do joelho de ratos [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013.A histamina é encontrada no líquido sinovial de indivíduos saudáveis e pacientes com diversos tipos ...
Silva, Eduardo Souza
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