Results 81 to 90 of about 53,829 (294)

Role of orexin receptors in histamine- and chloroquine-induced pruriceptive processing

Neuroscience Research
It is known that orexin peptides are involved in nociceptive processing, while little is known about the roles of these peptides in itch processing. To reveal the functions of orexin peptides in pruriceptive processing, orexin A (OX-A) and orexin B (OX-B)
Anna Kanemaru-Kawazoe, Hideki Funahashi, Yoichiro Kogoh, Ayaka Haruta-Tsukamoto, Yu Miyahara, Toshikazu Nishimori, Yasushi Ishida, Yoji Hirano   +7 more
doaj   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Calyx and dimorphic neurons of mouse Scarpa's ganglion express histamine H3 receptors

BMC Neuroscience, 2009
Background Histamine-related drugs are commonly used in the treatment of vertigo and related vestibular disorders. The site of action of these drugs however has not been elucidated yet.
Zucca Gianpiero, Zampini Valeria, Botta Laura, Tritto Simona, Valli Paolo, Masetto Sergio   +5 more
doaj   +1 more source

Nothing to sneeze at:histamine and histamine receptors in oral carcinogenesis [PDF]

, 2020
Oral squamous cell carcinoma (OSCC), the most common oral malignancy, shows an increasing rate of incidence worldwide. In spite of the recent advances in cancer research, OSCC therapy continues to have unfavourable outcomes, and thus, patient’s prognosis
Abdelhakim Salem, Salem, Abdelhakim, Tuula Salo, Salo, T. (Tuula), Salo, Tuula, Salem, A. (Abdelhakim)   +5 more
core   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source

Optimizing the Thermal Read-Out Technique for MIP-Based Biomimetic Sensors: Towards Nanomolar Detection Limits [PDF]

, 2013
In previous work, the novel heat-transfer method (HTM) for the detection of small molecules with Molecularly Imprinted Polymers (MIP)-type receptors was presented.
Peeters, Marloes, Bers, Karolien, Karolien Bers, Bers, K, Peeters, M, Ward de Ceuninck, Peeters M, de Ceuninck W, van Grinsven, B., Wagner, Patrick Hermann, Geerets B, Peeters, M.; id_orcid, Wagner, P., Bart van Grinsven, Bers, K., van Grinsven, Bart, Marloes Peeters, Geerets, Bram, van Grinsven B, Geerets, B., de Ceuninck, Ward, Bers K, de Ceuninck, W., Bram Geerets, Grinsven, B, Wagner P, Wagner, P, de Ceuninck, W, Bart Grinsven, van Grinsven, B, Geerets, B, Patrick Wagner, Wagner, Patrick   +32 more
core   +1 more source

Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi, Shotaro Aso, So Sato, Hideo Yasunaga   +3 more
wiley   +1 more source

Effects of Histamine and H1- and H2-Receptor Blocker on Food Intake, Food Passage Rate and in situ Nutrient Uptake from the Small Intestine of Chicken (Gallus domestics)

The Journal of Poultry Science, 2007
To implicate histamine and its receptors in feed intake and nutrient transport, White Leghorn cockerels of the same age and body weight were grouped randomly into six groups.
Abdul Nasir, Ram P. Moudgal, Narendra B. Singh   +2 more
doaj   +1 more source

Comportamento de coçar e nocicepção evidenciados após a aplicação facial de endotelina-1: um novo teste, uma nova oportunidade farmacológica [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2011O presente trabalho reproduziu o modelo experimental descrito por Shimada e Lamotte, (2008), e o
Gomes, Lenyta Oliveira
core  

Psychotropic medication use among community dwellers with and without Parkinson's disease – A nationwide cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen, Anna‐Maija Tolppanen, Valtteri Kaasinen, Marjaana Koponen, Sirpa Hartikainen   +4 more
wiley   +1 more source