Results 141 to 150 of about 92,808 (201)

Effects of olopatadine hydrochloride on substance P concentrations in nasal secretions and nasal symptoms. [PDF]

World J Exp Med
Katagiri F, Hatoyama-Tanaka S, Watanabe T, Takayanagi R, Suzuki M, Yamada Y.   +5 more
europepmc   +1 more source

Histamine H₁ Receptor-Mediated CREB Phosphorylation via G_q Protein Signaling and Arrestin Modulation. [PDF]

Pharmaceuticals (Basel)
Ogami R, Michinaga S, Iiboshi Y, Ogawa Y, Hishinuma S.   +4 more
europepmc   +1 more source

Wake-promoting neuromodulators in Alzheimer's disease: Implications for sleep and brain clearance. [PDF]

Alzheimers Dement
Pedersen TJ, Clemens SG, Winer JR, Sharma A, Falgàs N, Lucey BP, Gordon BA, Musiek ES.   +7 more
europepmc   +1 more source

Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2^-/- mice and human cholangiocarcinoma tumorigenesis.

Hepatology, 2018
Kennedy L, Hargrove L, Demieville J, Karstens W, Jones H, DeMorrow S, Meng F, Invernizzi P, Bernuzzi F, Alpini G, Smith S, Akers A, Meadows V, Francis H.   +13 more
europepmc   +1 more source

Neurotransmitter Dysregulation in Parkinson's Disease: Pathophysiological Insights and Therapeutic Perspectives. [PDF]

ACS Chem Neurosci
Aslan FS, Barut B, Ozturk S, Eyigurbuz T, Akyuz E.   +4 more
europepmc   +1 more source

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Histamine Receptor Assays

Current Protocols in Pharmacology, 2001
AbstractThis unit describes three standard in vitro bioassays for studying histamine H1, H2 and H3 receptors in isolated intact tissues removed from the guinea pig. Both the H1 and H3 receptor assays are based on preparations of the ileum, whereas the spontaneously beating right atrium assay is used for the H2‐receptor.This unit describes three ...
N P, Shankley, M F, Morton, G F, Watt
openaire   +2 more sources

Histamine H3 Receptor Agonists

Mini-Reviews in Medicinal Chemistry, 2004
The SAR of H3 ligands has been difficult to evaluate because of species differences, multiple isoforms and constitutive activity, among other complicating factors. A review is given of the sometimes-conflicting affinity, activity and efficacy data of H3 agonists that has been described in literature to date.
I J P, De Esch, K J, Belzar
openaire   +2 more sources

Histamine H4 receptor agonists

Bioorganic & Medicinal Chemistry Letters, 2010
Since its discovery 10 years ago the histamine H(4) receptor (H(4)R) has attracted attention as a potential drug target, for instance, for the treatment of inflammatory and allergic diseases. Potent and selective ligands including agonists are required as pharmacological tools to study the role of the H(4)R in vitro and in vivo.
Patrick, Igel, Stefan, Dove, Armin, Buschauer   +2 more
openaire   +2 more sources