Results 151 to 160 of about 618,306 (294)

Electrochemical aptasensors for ultrasensitive multiplexed detection: Towards a new era of precision diagnostics and environmental monitoring

VIEW, EarlyView.
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi, Ngoan Thi Thao Nguyen, Riccardo Zulli, Jacopo Giaretta, Fariba Dehghani, Syamak Farajikhah   +5 more
wiley   +1 more source

Molecular Determinant Underlying Selective Coupling of Primary G‐Protein by Class A GPCRs

Advanced Science
G‐protein‐coupled receptors (GPCRs) transmit downstream signals predominantly via G‐protein pathways. However, the conformational basis of selective coupling of primary G‐protein remains elusive.
Qingya Shen, Xinyan Tang, Xin Wen, Shizhuo Cheng, Peng Xiao, Shao‐Kun Zang, Dan‐Dan Shen, Lei Jiang, Yanrong Zheng, Huibing Zhang, Haomang Xu, Chunyou Mao, Min Zhang, Weiwei Hu, Jin‐Peng Sun, Yan Zhang, Zhong Chen   +16 more
doaj   +1 more source

Label-Free Investigations on the G Protein Dependent Signaling Pathways of Histamine Receptors. [PDF]

Int J Mol Sci, 2021
Seibel-Ehlert U, Plank N, Inoue A, Bernhardt G, Strasser A.   +4 more
europepmc   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Use of antihistamines in a physician's clinical practice

Терапевтический архив, 2014
Histamine that belongs to one of the most important mediators involved in the regulation of the body's vital functions plays a great role in the pathogenesis of different diseases.
L V Luss
doaj  

Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H_2-receptors [PDF]

, 1989
Schultz, Günther, Seifert, Roland, Buschauer, Armin, Burde, Rahel   +3 more
core   +1 more source

Co-localization of Histamine and eGFP in the Central Nervous System from pHdc-5’-UTR-eGFP Transformants of Drosophila melanogaster [PDF]

, 2009
Histamine is a biogenic amine synthesized by the enzyme histidine decarboxylase (Hdc) and used as a neurotransmitter in the central nervous system of Drosophila melanogaster.
Ervin, Wendi-Jo L.
core  

Distinct Nasal Microbiome Profiles and Prediction Model for Allergic Rhinitis, Nonallergic Rhinitis, and Healthy Children

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
The alpha and beta diversity of the nasal microbiome differed among children with allergic rhinitis (AR), nonallergic rhinitis (NAR), and healthy controls (HCs). Compared to HC, AR had more Escherichia‐Shigella, Negativicoccus, and Campylobacter, while NAR had more Dolosigranulum and fewer Enterobacteriaceae.
Kantima Kanchanapoomi, Iyarit Thaipisuttikul, Perapon Nitayanon, Witchaya Srisuwatchari, Punchama Pacharn, Nualanong Visitsunthorn, Orathai Jirapongsananuruk   +6 more
wiley   +1 more source

Safety, Efficacy, and Mechanism of Action of Budesonide in Rhinitis and Rhinosinusitis: A Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy, Lei Cheng, De‐Yun Wang   +2 more
wiley   +1 more source

Amitriptyline functionally antagonizes cardiac H₂ histamine receptors in transgenic mice and human atria. [PDF]

Naunyn Schmiedebergs Arch Pharmacol, 2021
Neumann J, Binter MB, Fehse C, Marušáková M, Büxel ML, Kirchhefer U, Hofmann B, Gergs U.   +7 more
europepmc   +1 more source