Results 11 to 20 of about 58,945 (147)

Applying Surface Plasmon Resonance to Monitor the IgE-Mediated Activation of Human Basophils

Allergology International, 2008
Background: The histamine releasing test which detects histamine released from basophils in vitro is safe, sensitive and widely used for clinical examination in the field of allergy.
Hidenori Suzuki, Yuhki Yanase, Tomoko Tsutsui, Kaori Ishii, Takaaki Hiragun, Michihiro Hide   +5 more
doaj   +1 more source

IL-33 and Superantigenic Activation of Human Lung Mast Cells Induce the Release of Angiogenic and Lymphangiogenic Factors

Cells, 2021
Human lung mast cells (HLMCs) express the high-affinity receptor FcεRI for IgE and are strategically located in different compartments of human lung, where they play a role in several inflammatory disorders and cancer. Immunoglobulin superantigens (e.g.,
Leonardo Cristinziano, Remo Poto, Gjada Criscuolo, Anne Lise Ferrara, Maria Rosaria Galdiero, Luca Modestino, Stefania Loffredo, Amato de Paulis, Gianni Marone, Giuseppe Spadaro, Gilda Varricchi   +10 more
doaj   +1 more source

Lysophosphatidic Acid (LPA) Induces Plasma Exudation and Histamine Release in Mice via LPA Receptors

Journal of Pharmacological Sciences, 2006
.: Lysophosphatidic acid (LPA), the simplest of the water-soluble phospholipids, can evoke various biological responses. The present study examined the activity of LPA to induce plasma exudation and histamine release in mice.
Terumasa Hashimoto, Hisayuki Ohata, Kazuo Honda   +2 more
doaj   +1 more source

Role of Substance P on Histamine H3 Antagonist-Induced Scratching Behavior in Mice

Journal of Pharmacological Sciences, 2006
.: The purpose of the present study was to investigate the involvement of chemical mediators, other than histamine, in the scratching behavior induced by H3 antagonists.
Maria Alejandra Hossen, Toshio Inoue, Yoshifumi Shinmei, Yoko Fujii, Takeshi Watanabe, Chiaki Kamei   +5 more
doaj   +1 more source

Histamine: a new immunomodulatory player in the neuron-glia crosstalk

Frontiers in Cellular Neuroscience, 2014
Histamine is an amine acting as a major peripheral inflammatory mediator. In the brain, histamine was initially viewed as a neurotransmitter, but new evidences support its involvement in the modulation of innate immune responses. Recently, we showed that
Sandra M Rocha, Joel ePires, Marta eEsteves, Graça eBaltazar, Liliana eBernardino   +4 more
doaj   +1 more source

Basophils activation of patients with chronic spontaneous urticaria in response to C5a despite failure to respond to IgE-mediated stimuli

Frontiers in Immunology, 2022
Urticaria is characterized by the occurrence of wheals and flares in response to vasoactive mediators, such as histamine. Various studies have suggested the involvement of basophils in the pathogenesis of chronic spontaneous urticaria (CSU).
Daiki Matsubara, Yuhki Yanase, Kaori Ishii, Shunsuke Takahagi, Akio Tanaka, Koichiro Ozawa, Michihiro Hide, Michihiro Hide   +7 more
doaj   +1 more source

Pancuronium and histamine release [PDF]

Canadian Anaesthetists’ Society Journal, 1978
Both d-tubocurarine and pancuronium release histamine in the skin: both have been shown to cause bronchospasm after intravenous injection. It is unlikely that skin testing with either drug will detect an individual susceptibility to bronchospasm, except as a non-specific test for atopy.
openaire   +2 more sources

Microplate Assay for Measurement of Histamine Release from Mast Cells

BioTechniques, 1997
A microplate-format assay for measurement of histamine release by activated rat peritoneal mast cells, with accompanying microplate-format spectrofluorometric assay of histamine, is demonstrated.
Joseph A. Price
doaj   +1 more source

Role of Histamine and Symbiotic Microbiota in Realizing the Allergopathology Risks in the First Months of Life

Детские инфекции (Москва), 2019
The purpose of research is to designate the significance of histamine and symbiotic microbiota in the development of allergopathology  in the first months of baby’s life.As a result of the study of 80 «mother-child» pairs with a burdened genetic history ...
L. A. Lityaeva, V. A. Zhirnov, S. Y. Nosyreva   +2 more
doaj   +1 more source

The role of the mast cell in pigmentation disorders

Pigment International, 2021
The mast cell is a critical mediator of the inflammatory response by secreting histamine. While histamine is currently not regarded as a melanogen, recent studies have shown histamine release to induce melanogenesis, melanocyte proliferation and ...
Valdemar Wendelboe Nielsen, Simon Francis Thomsen   +1 more
doaj   +1 more source