Results 11 to 20 of about 2,226,679 (338)

Ephedrae herba in Mao-Bushi-Saishin-To Inhibits IgE-Mediated Histamine Release and Increases cAMP Content in RBL-2H3 Cells

Journal of Pharmacological Sciences, 2004
Acute effect of Mao-Bushi-Saishin-To (Ma-Huang-Fu-Zi-Xi-Xin-Tang in Chinese: MBS) on histamine release was investigated. The IgE-mediated anaphylaxic response in Wistar rats was significantly suppressed by MBS and Mao.
Shin-ya Saito, Yukiko Maruyama, Sachie Kamiyama, Norimichi Nakahata, Yasushi Ohizumi   +4 more
doaj   +1 more source

Effect of propolis extract on guines pig lung mast cell

Journal of Venomous Animals and Toxins including Tropical Diseases, 2005
The direct effect of ethanolic extract of propolis on guinea pig lung cell suspension containing mast cells, as well as its influence on the histamine release induced by antigen (ovoalbumin 10 mug/ml) and ionophore A 23187 (3 muM) were investigated ...
R. O. Orsi, J. M. Sforcin, S. R. C. Funari, J. C. Gomes   +3 more
doaj   +1 more source

Optogenetic-Mediated Release of Histamine Reveals Distal and Autoregulatory Mechanisms for Controlling Arousal

Journal of Neuroscience, 2014
Histaminergic neurons in the tuberomammillary nucleus (TMN) are an important component of the ascending arousal system and may form part of a “flip–flop switch” hypothesized to regulate sleep and wakefulness.
Rhîannan H. Williams, Melissa J. Chee, D. Kroeger, L. Ferrari, E. Maratos-Flier, T. Scammell, E. Arrigoni   +6 more
semanticscholar   +1 more source

Role of protein kinase A in the inhibition of human mast cell histamine release by β-adrenergic receptor agonists

Allergology International, 2002
Background: Although β-adrenergic receptor agonists inhibit antigen-induced release of histamine, leukotrienes and prostaglandin D2 from human lung fragments, dispersed human lung mast cells and human skin mast cells, subcellular mechanisms for the ...
Toshinobu Kato, Masahiro Kimata, Toshikazu Tsuji, Michitaka Shichijo, Masayuki Murata, Toru Miura, Isao Serizawa, Naoki Inagaki, Hiroichi Nagai   +8 more
doaj   +1 more source

Lysophosphatidic Acid (LPA) Induces Plasma Exudation and Histamine Release in Mice via LPA Receptors

Journal of Pharmacological Sciences, 2006
.: Lysophosphatidic acid (LPA), the simplest of the water-soluble phospholipids, can evoke various biological responses. The present study examined the activity of LPA to induce plasma exudation and histamine release in mice.
Terumasa Hashimoto, Hisayuki Ohata, Kazuo Honda   +2 more
doaj   +1 more source

IL-33 and Superantigenic Activation of Human Lung Mast Cells Induce the Release of Angiogenic and Lymphangiogenic Factors

Cells, 2021
Human lung mast cells (HLMCs) express the high-affinity receptor FcεRI for IgE and are strategically located in different compartments of human lung, where they play a role in several inflammatory disorders and cancer. Immunoglobulin superantigens (e.g.,
Leonardo Cristinziano, Remo Poto, Gjada Criscuolo, Anne Lise Ferrara, Maria Rosaria Galdiero, Luca Modestino, Stefania Loffredo, Amato de Paulis, Gianni Marone, Giuseppe Spadaro, Gilda Varricchi   +10 more
doaj   +1 more source

Applying Surface Plasmon Resonance to Monitor the IgE-Mediated Activation of Human Basophils

Allergology International, 2008
Background: The histamine releasing test which detects histamine released from basophils in vitro is safe, sensitive and widely used for clinical examination in the field of allergy.
Hidenori Suzuki, Yuhki Yanase, Tomoko Tsutsui, Kaori Ishii, Takaaki Hiragun, Michihiro Hide   +5 more
doaj   +1 more source

Histamine Induces ATP Release from Human Subcutaneous Fibroblasts, via Pannexin-1 Hemichannels, Leading to Ca2+ Mobilization and Cell Proliferation*

Journal of Biological Chemistry, 2013
Background: Chronic pain may involve connective tissue remodeling due to inflammatory mediators. Results: Histamine H1 receptor activation causes ATP release from human subcutaneous fibroblasts via pannexin-1 hemichannels.
A. R. Pinheiro, Diogo Paramos-de-Carvalho, M. Certal, M. A. Costa, Cristina Costa, M. T. Magalhães-Cardoso, F. Ferreirinha, J. Sévigny, P. Correia-de-Sá   +8 more
semanticscholar   +1 more source

Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells

Archives of pharmacal research, 2008
Hyo-Hyun Park, Soyoung Lee, H. Son, Seung-Bin Park, Mi‐Sun Kim, Eun‐Ju Choi, T. S. Singh, J. Ha, Maan-Gee Lee, Jungeun Kim, M. Hyun, T. Kwon, Y. Kim, Sang-Hyun Kim   +13 more
semanticscholar   +3 more sources

Role of Substance P on Histamine H3 Antagonist-Induced Scratching Behavior in Mice

Journal of Pharmacological Sciences, 2006
.: The purpose of the present study was to investigate the involvement of chemical mediators, other than histamine, in the scratching behavior induced by H3 antagonists.
Maria Alejandra Hossen, Toshio Inoue, Yoshifumi Shinmei, Yoko Fujii, Takeshi Watanabe, Chiaki Kamei   +5 more
doaj   +1 more source