Results 31 to 40 of about 66,422 (214)
The role of the mast cell in pigmentation disorders
Pigment International, 2021 The mast cell is a critical mediator of the inflammatory response by secreting histamine. While histamine is currently not regarded as a melanogen, recent studies have shown histamine release to induce melanogenesis, melanocyte proliferation and ...
Valdemar Wendelboe Nielsen +1 more
doaj +1 more source
Current Opinion in Immunology, 1996 There is increasing evidence that human basophils accumulate at sites of chronic inflammation, and, in particular, in allergic asthma. Investigators have, therefore, become very interested in identifying proteins that activate these cells. Recently, the gene encoding a candidate for this function, a novel molecule, the IgE-dependent histamine-releasing
openaire +2 more sources
Perioperative uses of histamine antagonists
, 1990 Histamine release and adverse pseudoallergic/allergic reactions during the perioperative period occur frequently. The incidence of such reactions is 20%-30% for all grades of severity, 1%-5% for systemic reactions, and 0.1%-0.5% for life-threatening ...
Lorenz, Wilfried +3 more
core +1 more source
BMC Immunology, 2004 Background Parasite-specific IgE levels correlate with human resistance to reinfection with Schistosoma spp. after chemotherapy. Although the role of eosinophils in schistosomiasis has been the focus of a great deal of important research, the involvement
Kazibwe Francis +15 more
doaj +1 more source
, 1993 Many drugs, especially when given in rapid sequence can cause histamine release. Ten healthy volunteers were premedicated with diazepam 10 mg.70 kg-1 i.v. and lormetazepam 1 mg.70 kg-1 i.v., respectively, 30 min prior to etomidate 0.15 mg.kg-1 i.v.
Doenicke, A. +4 more
core +1 more source
Sleep-wake sensitive mechanisms of adenosine release in the basal forebrain of rodents : an in vitro study [PDF]
, 2013 Adenosine acting in the basal forebrain is a key mediator of sleep homeostasis. Extracellular adenosine concentrations increase during wakefulness, especially during prolonged wakefulness and lead to increased sleep pressure and subsequent rebound sleep.
Sims, Robert E. +11 more
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Prostaglandin D2 Inhibits IgE-Mediated Scratching by Suppressing Histamine Release From Mast Cells
Journal of Pharmacological Sciences, 2005 Effects of prostaglandin (PG) D2, PGE2, and PGI2 on itch-associated scratching responses of mice and histamine release from the rat basophilic leukemia cell line RBL-2H3 were examined.
Yuki Hashimoto +3 more
doaj +1 more source
Granuloma pouch and skin histamine of the rat
, 1958 Using the granuloma pouch technique of SELYE, effect of modification in local histamine on the inflammatory tissue reactions was examined in rats. The increase in the weight of pouch wall and histological inflammatory changes were distinctly inhibited in
Irino, Shozo
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The Journal of Headache and PainBackground Trigeminal afferents innervating the meninges are likely involved in the generation of headaches and migraine. A major proportion of these afferents can release calcitonin gene-related peptide (CGRP) upon stimulation. Several substances, among
Fernando de Mora +5 more
doaj +1 more source
Histamine modulates microglia function
Journal of Neuroinflammation, 2012 Background Histamine is commonly acknowledged as an inflammatory mediator in peripheral tissues, leaving its role in brain immune responses scarcely studied.
Ferreira Raquel +6 more
doaj +1 more source