Results 51 to 60 of about 66,422 (214)

Histamine activates an intracellular Ca2+ signal in normal human lung fibroblast WI-38 cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
Histamine is an inflammatory mediator that can be released from mast cells to induce airway remodeling and cause persistent airflow limitation in asthma.
Roberto Berra-Romani   +11 more
doaj   +1 more source

Functional characterisation of the novel histamine H(3) receptor agonist, VUF 5810, on the guinea-pig isolated ileum

open access: yes, 2003
It is known that the activation of prejunctionally-located histamine H3 receptors down-regulates the exocytotic acetylcholine release from the myenteric plexus and thus produces a negative control on the intestinal motility [1].
POZZOLI, Cristina   +7 more
core   +1 more source

Organic cation transporter-3 mediates exogenous histamine uptake by primary mast cells

open access: yesJournal of Allergy and Clinical Immunology: Global
Background: Mast cells exhibit uptake of histamine from the extracellular microenvironment, which can affect the extent of histamine release following their activation. How mast cells take up exogenous histamine, however, is not fully understood. Organic
Thuy-An Nguyen, MD   +11 more
doaj   +1 more source

Histamine H3 and H4 receptors are expressed on distinct endocrine cell types in the rat fundic mucosa

open access: yes, 2007
The present study was designed to explore the expression and distribution of histamine H3 and H4 receptors within the rat gastric fundus by immunohistochemistry using our unique immunological probes.
SHENTON F. C.   +7 more
core   +1 more source

Role of histamine in the inhibitory effects of phycocyanin in experimental models of allergic inflammatory response

open access: yesMediators of Inflammation, 2002
It has recently been reported that phycocyanin, a biliprotein found in the blue-green microalgae Spirulina, exerts anti-inflammatory effects in some animal models of inflammation.
D. Remirez, N. Ledón, R. González
doaj   +1 more source

Papel dos receptores histaminérgicos da medula espinhal na inflamação articular de ratos e sua possível contribuição como adjuvante para os efeitos da morfina [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaA medula espinhal é conhecida por ser um centro de controle ortodrômico (nocicepção), bem como antidrômico ...
Silva, Taciane Stein da
core  

Inhibition of NO-synthase and degranulation of rat omental mast cells in vitro

open access: yesMediators of Inflammation, 1996
Mast cell amines, platelet-activating factor (PAF), thromboxanes and leukotrienes have been shown to be released during nitric oxide-synthase inhibition in the rat intestine.
A. M. Northover, B. J. Northover
doaj   +1 more source

Histamine release assay.

open access: yes, 2013
Basophils in leukocyte suspension were stripped off the bound IgE. Stripped basophils were sensitized with sera of kidney bean hypersensitive patients. The sensitized basophils were stimulated with kidney bean extract.
Ramesh C. Sahoo (340009)   +5 more
core   +1 more source

Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers [PDF]

open access: yes, 2003
Objectives: Our study sought to elucidate the role of oxidative stress for shedding of tumor necrosis factor-α (TNF-α) and for activating TNF-α-converting enzyme (TACE).
Welsch, Ulrich   +4 more
core   +1 more source

Role of protein phosphatases inhibitors on the histamine release and the functional desensitization in human lung mast cells

open access: yesJournal of Research in Medical Sciences, 2014
Background: The β2-adrenoceptor agonist, isoprenaline, is an effective inhibitor of histamine release from human lung mast cells (HLMC). Since phosphorylations of the β2-adrenoceptors are probably important in inducing desensitization, we sought to ...
Reza Bastan   +4 more
doaj  

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