Results 1 to 10 of about 26,872 (162)
Anti-Allergic Potential of Cinnamaldehyde via the Inhibitory Effect of Histidine Decarboxylase (HDC) Producing Klebsiella pneumonia [PDF]
Molecules, 2020 Allergy is an immunological disorder that develops in response to exposure to an allergen, and histamines mediate these effects via histidine decarboxylase (HDC) activity at the intracellular level.
Lorina I. Badger-Emeka +3 more
doaj +2 more sources
Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice [PDF]
Journal of Diabetes Research, 2015 Recent evidence has highlighted the role of histamine in inflammation. Since this monoamine has also been strongly implicated in the pathogenesis of type-1 diabetes, we assessed its effect in the nonobese diabetic (NOD) mouse model.
Manal Alkan +5 more
doaj +2 more sources
Histidine Decarboxylase Expression in Human Melanoma [PDF]
Journal of Investigative Dermatology, 2000 Histamine has been implicated as one of the mediators involved in regulation of proliferation in both normal and neoplastic tissues. Histidine decarboxylase, the only enzyme that catalyzes the formation of histamine from L-histidine, is an essential regulator of histamine levels.
Zsuzsa Darvas +2 more
exaly +3 more sources
Histidine alleviates Hashimoto’s thyroiditis via the neutrophil extracellular traps-NF-κB signaling pathway [PDF]
Scientific ReportsMetabolite abnormalities are potentially implicated in pathogenesis of Hashimoto’s thyroiditis (HT). An in-depth study of the relationship between HT and small molecule metabolites, as well as its pathogenesis, can help enhance the diagnosis, prognosis ...
Tingting Ding +8 more
doaj +2 more sources
L-histidine decarboxylase and Tourette's syndrome. [PDF]
N Engl J Med, 2010 Tourette's syndrome is a common developmental neuropsychiatric disorder characterized by chronic motor and vocal tics. Despite a strong genetic contribution, inheritance is complex, and risk alleles have proven difficult to identify. Here, we describe an analysis of linkage in a two-generation pedigree leading to the identification of a rare functional
Ercan-Sencicek AG +27 more
europepmc +5 more sources
Frontiers in Pharmacology, 2022 This study aimed to analyze and discuss the biomarkers of PEGylated liposomal doxorubicin (PLD) injection-induced hypersensitivity reactions (HSRs) in advanced breast cancer patients.
Wei Zhuang +13 more
doaj +1 more source
Histamine derived from probiotic Lactobacillus reuteri suppresses TNF via modulation of PKA and ERK signaling. [PDF]
PLoS ONE, 2012 Beneficial microbes and probiotic species, such as Lactobacillus reuteri, produce biologically active compounds that can modulate host mucosal immunity. Previously, immunomodulatory factors secreted by L. reuteri ATCC PTA 6475 were unknown.
Carissa M Thomas +8 more
doaj +1 more source
Tadr is an axonal histidine transporter required for visual neurotransmission in Drosophila
eLife, 2022 Neurotransmitters are generated by de novo synthesis and are essential for sustained, high-frequency synaptic transmission. Histamine, a monoamine neurotransmitter, is synthesized through decarboxylation of histidine by histidine decarboxylase (Hdc ...
Yongchao Han, Lei Peng, Tao Wang
doaj +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2023 Background & Aims: Histamine in the stomach traditionally is considered to regulate acid secretion but also has been reported to participate in macrophage differentiation, which plays an important role in tissue homeostasis.
Kwang H. Kim +12 more
doaj +1 more source
Production of biogenic amines by Enterococci
Czech Journal of Food Sciences, 2009 Enterococci were presented in all tested samples of raw cow milk (six samples) at the level 103-105 CFU/ml, fresh cheeses (five samples) at the level 102-106 CFU/g and semi-hard cheeses (five samples) at the level 103-105 CFU/g.
Kateřina Kučerová +4 more
doaj +1 more source