Results 11 to 20 of about 41,640 (220)

L-histidine decarboxylase and Tourette's syndrome. [PDF]

N Engl J Med, 2010
Tourette's syndrome is a common developmental neuropsychiatric disorder characterized by chronic motor and vocal tics. Despite a strong genetic contribution, inheritance is complex, and risk alleles have proven difficult to identify. Here, we describe an analysis of linkage in a two-generation pedigree leading to the identification of a rare functional
Ercan-Sencicek AG, Stillman AA, Ghosh AK, Bilguvar K, O'Roak BJ, Mason CE, Abbott T, Gupta A, King RA, Pauls DL, Tischfield JA, Heiman GA, Singer HS, Gilbert DL, Hoekstra PJ, Morgan TM, Loring E, Yasuno K, Fernandez T, Sanders S, Louvi A, Cho JH, Mane S, Colangelo CM, Biederer T, Lifton RP, Gunel M, State MW.   +27 more
europepmc   +7 more sources

Histidine Decarboxylase Expression in Human Melanoma [PDF]

Journal of Investigative Dermatology, 2000
Histamine has been implicated as one of the mediators involved in regulation of proliferation in both normal and neoplastic tissues. Histidine decarboxylase, the only enzyme that catalyzes the formation of histamine from L-histidine, is an essential regulator of histamine levels.
Darvas, Zsuzsa, Hegyesi, Hargita, László, Valéria, Bencsáth, Márta, Falus, András, Haak-Frendscho, Mary, Kárpáti, Sarolta, Hoffman, Randall L., Szalai, Csaba, Fürész, József, Timár, József, Bata-Csörgõ, Zsuzsanna, Szabad, Gábor, Pivarcsi, Andor, Pállinger, Éva, Kemény, Lajos, Horváth, Attila, Dobozy, Attila   +17 more
openaire   +4 more sources

Expression of Histidine Decarboxylase and Its Roles in Inflammation. [PDF]

Int J Mol Sci, 2019
Hirasawa N.
europepmc   +2 more sources

Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice. [PDF]

Neuron, 2014
Baldan LC, Williams KA, Gallezot JD, Pogorelov V, Rapanelli M, Crowley M, Anderson GM, Loring E, Gorczyca R, Billingslea E, Wasylink S, Panza KE, Ercan-Sencicek AG, Krusong K, Leventhal BL, Ohtsu H, Bloch MH, Hughes ZA, Krystal JH, Mayes L, de Araujo I, Ding YS, State MW, Pittenger C.   +23 more
europepmc   +2 more sources

Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms [PDF]

, 2018
Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces acute proinflammatory responses, but it also induces delayed systemic immunosuppressive effects ...
FitzGerald, Garret A., Kaplan, Mark H., Ocana, Jesus A., Pawelzik, Sven-Christian, Romer, Eric, Sahu, Ravi, Travers, Jeffrey B.   +6 more
core   +1 more source

Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]

, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana, Guma, Monica, Murillo-Saich, Jessica D   +2 more
core   +2 more sources

Identification and typization of bacteria of the genus Enterococcus supposed to be used for the production of functional foods

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2007
In this study, the species identification of 12 probiotic strains of the genus Enterococcus from Culture Collection of Dairy Microorganisms Lactoflora (CCDM, Milcom, Tábor, Czech Republic) were done using PCR described by DUTKA-MALEN et al. (1995).
Radka Burdychová
doaj   +1 more source

High-throughput DNA sequencing to survey bacterial histidine and tyrosine decarboxylases in raw milk cheeses [PDF]

, 2015
peer-reviewedBackground The aim of this study was to employ high-throughput DNA sequencing to assess the incidence of bacteria with biogenic amine (BA; histamine and tyramine) producing potential from among 10 different cheeses varieties.
Cotter, Paul D., Fallico, Vincenzo, Giblin, Linda, McSweeney, Paul L. H., O'Sullivan, Daniel, O'Sullivan, Orla, Sheehan, Diarmuid (JJ)   +6 more
core   +1 more source

ClC transporter activity modulates histidine catabolism in Lactobacillus reuteri by altering intracellular pH and membrane potential

Microbial Cell Factories, 2019
Background Histamine is a key mediator of the anti-inflammatory activity conferred by the probiotic organism Lactobacillus reuteri ATCC PTA 6475 in animal models of colitis and colorectal cancer. In L.
Anne E. Hall, Melinda A. Engevik, Numan Oezguen, Anthony Haag, James Versalovic   +4 more
doaj   +1 more source

Molecular Regulation of Histamine Synthesis

Frontiers in Immunology, 2018
Histamine is a critical mediator of IgE/mast cell-mediated anaphylaxis, a neurotransmitter and a regulator of gastric acid secretion. Histamine is a monoamine synthesized from the amino acid histidine through a reaction catalyzed by the enzyme histidine ...
Hua Huang, Hua Huang, Yapeng Li, Jinyi Liang, Jinyi Liang, Fred D. Finkelman, Fred D. Finkelman   +6 more
doaj   +1 more source