Results 221 to 230 of about 42,773 (253)

Primary structure of histidine decarboxylase

Bulletin of Experimental Biology and Medicine, 1989
The results of investigation of the primary structure of the Histidine Decarboxylase Micrococcus sp. n. are reported. A comparison of the primary structure of the Histidine Decarboxylase Micrococcus sp. n. with that of the Lactobacillus 30a enzyme suggests the alignment with a 52% identity. It is therefore highly probable that two proteins have evolved
V N, Prozorovskiĭ, A E, Alekseeva, O G, Grebenshchikova   +2 more
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A rapid histidine decarboxylase assay

Analytical Biochemistry, 1978
Abstract Histidine decarboxylase (EC 4.1.1.22) catalyzes the conversion of histidine to histamine. Because current assays for enzyme activity are time consuming and require additional enzymes or large amounts of tissue, a rapid radioisotopic assay was devised.
R, Roskoski, L M, Roskoski
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Histidine Decarboxylase and Dopa Decarboxylase

1970
The concept of neural transmission is intimately connected with that of the functional significance of the biogenic amines. Although so far relatively few amines have been recognized as transmitter compounds, it is frequently assumed that all amines in the central nervous systems (CNS) have some function related to the control or facilitation of ...
Dorothea Aures, Rolf Håkanson, William G. Clark   +2 more
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Peptide inhibition of mammalian histidine decarboxylase

Agents and Actions, 1979
The hypothesis that N-terminal histidine peptides might act as inhibitors to histidine decarboxylase was investigated. A murine mastocytoma was utilized as enzyme source. The crude extract of this tissue exhibits high rates of decarboxylation of both histidine and DOPA and was used to establish the specificity in the effect of the compounds tested. For
L, Hammar, U, Ragnarsson
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PROPERTIES OF RAT BRAIN HISTIDINE DECARBOXYLASE

Journal of Neurochemistry, 1976
Abstract– The properties of histidine decarboxylase (l‐histidine carboxylyase EC 4.1,1.22) have been studied in a whole rat brain homogenate. Optimum pH depended upon substrate concentration; the variations of Km and Vmax were determined as a function of pH.
J M, Palacios, G, Mengod, F, Picatoste, M, Grau, I, Blanco   +4 more
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A microassay for mammalian histidine decarboxylase

Analytical Biochemistry, 1975
Abstract This report describes a microassay procedure for mammalian histidine decarboxylase (HDC) based on the measurement of [ 14 C]O 2 formed from l -[1- 14 C]histidine. This assay is particularly useful for quick measurement of HDC activity both in microgram quantities of cell or tissue extract and in tissues that contain significant levels of ...
D G, Ritchie, D A, Levy
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Bacterial histidine decarboxylase in rat stomach

European Journal of Pharmacology, 1970
Abstract Two histadine decarboxylase activities have been found in rat stomach. One, in the supernatant fraction of stomach homogenate, had optimum activity at pH 7 and appeared similar to the specific mammalian L-histidine decarboxylase (EC 4.1.1.22) descrideb by other workers.
M A, Beaven, Z, Horáková, W B, Severs
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Histidine decarboxylase inhibition and gastric secretion

The American Journal of Digestive Diseases, 1967
In a series of rats whose histamine formation was blocked by either pyridoxine deficiency or decarboxylase inhibition with 4-bromo-3-hydroxybenzy-oxyamine dihydrogen phosphate (NSD-1055), we found that basal and gastrin-stimulated gastric secretion was markedly lowered.
W R, Thayer, H F, Martin
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Mammalian histidine decarboxylase: Effect by protein kinase on mouse mastocytoma histidine decarboxylase

Agents and Actions, 1983
Mouse mastocytoma histidine decarboxylase is decreased in activity when, in crude preparations, incubated with a cAMP-dependent protein kinase. This effect was not seen with purified preparations of the histidine decarboxylase (specific activity 7-13 mumol X mg-1 X h-1).
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4 The Histidine Decarboxylases

1967
Publisher Summary This chapter explores that histidine, β-4(5)-imidazolyl-α-aminopropionic acid (III), is one of the essential amino acids. From the pharmacological point of view, it is of particular importance as it is the immediate precursor of the highly active amine histamine, β-4(5)-imidazolylethylamine (IV).
D.M. Shepherd, D. MaCkay
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