Results 51 to 60 of about 26,592 (294)
Enhanced water affinity of histidine by transition metal ions [PDF]
arXiv, 2020 Transitional metal ions widely exist in biological environments and are crucial to many life-sustaining physiological processes. Recently, transition metal ion such as Cu$^{2+}$, Zn$^{2+}$, Ni$^{2+}$, have been shown can increase the solubilities of aromatic biomolecules. Comparing with Cu$^{2+}$, Zn$^{2+}$ shows less enhancement to the solubilities of
arxiv
Interdisciplinary Medicine, EarlyView.Left: The disruption of the balance between carcinogenic bacteria and probiotics mediated by antibiotics, protein, and glucose intake. Middle: The gut microbiota‐derived amino acids, primarily through tryptophan, tyrosine, arginine, and branched‐chain amino acid pathways, regulate glioma development via mechanisms such as AHR activation, metabolic ...
Qianquan Ma +10 more
wiley +1 more source
Kovalen: Jurnal Riset KimiaHistamine in fish is formed due to histidine decarboxylase which occurs due to decay by bacteria. In the Maluku community, melinjo leaves (Gnetum gnemon) are used as boiled water in processing rotten fish so that the decay process is inhibited.
Nelspon Gazpersz +5 more
doaj +1 more source
Chiral Interactions of Histidine in a Hydrated Vermiculite [PDF]
, 2010 Recent work suggests a link between chiral asymmetry in the amino acid iso-valine extracted from the Murchison meteorite and the extent of hydrous alteration. We present the results of neutron scattering experiments on an exchanged, 1-dimensionally ordered n-propyl ammonium vermiculite clay. The vermiculite gel has a (001) d-spacing of order 5nm at the
arxiv +1 more source
Internal water and microsecond dynamics in myoglobin [PDF]
J. Phys. Chem. B 117, 14676-14687 (2013), 2013 Myoglobin (Mb) binds diatomic ligands, like O$_2$, CO, and NO, in a cavity that is only transiently accessible. Crystallography and molecular simulations show that the ligands can migrate through an extensive network of transiently connected cavities, but disagree on the locations and occupancy of internal hydration sites. Here, we use water $^2$H and $
arxiv +1 more source
Histidine decarboxylase in experimental tumours
Journal of Pharmacy and Pharmacology, 1966 Abstract Histidine decarboxylase activity has been demonstrated in some experimental tumours by direct enzyme assay. The kinetic properties of semi-purified preparations of the histamine-forming enzyme from Rous rat sarcoma and Walker rat mammary carcinoma were similar to those of the “specific” histidine decarboxylase of the foetal rat.
openaire +3 more sources
Covalently bound substrate at the regulatory site triggers allosteric enzyme activation [PDF]
, 2008 The mechanism by which the enzyme pyruvate decarboxylase from yeast is activated allosterically has been elucidated. A total of seven three-dimensional structures of the enzyme, of enzyme variants or of enzyme complexes form two yeast species (three of ...
Georg Wille +5 more
core +1 more source
Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei [PDF]
, 2017 Trypanosoma brucei, protozoan parasites that cause human African trypanosomiasis (HAT), depend on ornithine uptake and metabolism by ornithine decarboxylase (ODC) for survival. Indeed, ODC is the target of the WHO "essential medicine" eflornithine, which
Alsford, Sam +5 more
core +4 more sources
Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]
, 2020 Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana +2 more
core +2 more sources
FASEB BioAdvances, EarlyView.Deuterium, a heavy isotope of hydrogen, is universal in nature, but it disrupts the mitochondrial ATPase pumps. One mechanism that biological organisms may use to reduce deuterium levels in the mitochondria is to sequester deuterium bound to carbon atoms in a small set of organic molecules that have a unique configuration to support such trapping ...
Stephanie Seneff +2 more
wiley +1 more source