Results 41 to 50 of about 87,659 (287)

HAMP Domain Rotation and Tilting Movements Associated with Signal Transduction in the PhoQ Sensor Kinase

mBio, 2015
HAMP domains are α-helical coiled coils that often transduce signals from extracytoplasmic sensing domains to cytoplasmic domains. Limited structural information has resulted in hypotheses that specific HAMP helix movement changes downstream enzymatic ...
Susana Matamouros, Kyle R. Hager, Samuel I. Miller   +2 more
doaj   +1 more source

The histidine kinase-related domain participates in phytochrome B function but is dispensable [PDF]

, 2000
Phytochromes are photoreceptors that control many plant light responses. Phytochromes have two carboxyl-terminal structural domains called the PAS repeat domain and the histidine kinase-related domain.
Krall, L., Reed, J. W.
core   +2 more sources

NM23-H1: a Metastasis-Associated Gene

Taiwanese Journal of Obstetrics & Gynecology, 2006
The protein product of nm23-H1 gene has activity of nucleoside diphosphate (NDP) kinase, which catalyzes the phosphorylation of nucleoside diphosphates to the corresponding nucleoside triphosphates.
Yi-Torng Tee, Gin-Den Chen, Long-Yau Lin, Jiunn-Liang Ko, Po-Hui Wang   +4 more
doaj   +1 more source

A Unique Sensor Histidine Kinase [PDF]

Journal of Bacteriology, 2009
Sporulation initiation in Bacillus species is controlled by an extended version of two-component signal transduction systems, termed phosphorelay ([4][1]). The cascade of His→Asp→His→Asp phosphotransfer is typically initiated by the ATP-dependent autophosphorylation of the histidine ...
openaire   +2 more sources

Alterations in reversible protein histidine phosphorylation as intracellular signals in cardiovascular disease

Frontiers in Pharmacology, 2015
Reversible phosphorylation of amino acid side chains in proteins is a frequently used mechanism in cellular signal transduction and alterations of such phosphorylation patterns are very common in cardiovascular diseases.
Thomas Wieland, Paul V. Attwood
doaj   +1 more source

Cryo-EM structure of the QseG-QseE complex reveals an accessory protein-driven two-component system activation mechanism

mBio
The two-component system (TCS) enables bacteria to sense and respond to environmental changes through histidine kinase-mediated signaling cascades. Although the core components of TCSs have been extensively studied, the molecular basis of accessory ...
Piqian Gong, Guobang Li, Weixun Li, Mengyuan Xu, Xuyao Jiao, Xudong Chen, Beile Gao, Xiang Gao   +7 more
doaj   +1 more source

Characterization of CHARK, an unusual cytokinin receptor of rice

Scientific Reports, 2021
The signal transduction of the plant hormone cytokinin is mediated by a His-to-Asp phosphorelay. The canonical cytokinin receptor consists of an extra cytoplasmic hormone binding domain named cyclase/histidine kinase associated sensory extracellular ...
Mhyeddeen Halawa, Anne Cortleven, Thomas Schmülling, Alexander Heyl   +3 more
doaj   +1 more source

Hybrid histidine kinases in pathogenic fungi [PDF]

Molecular Microbiology, 2015
SummaryHistidine kinases (HK) sense and transduce via phosphorylation events many intra‐ and extracellular signals in bacteria, archaea, slime moulds and plants. HK are also widespread in the fungal kingdom, but their precise roles in the regulation of physiological processes remain largely obscure.
Defosse, Tatiana, Sharma, Anupam, Mondal, Alok, Dugé de Bernonville, Thomas, Latgé, Jean-Paul, Calderone, Richard, Giglioli-Guivarc'H, Nathalie, Courdavault, Vincent, Clastre, Marc, Papon, Nicolas   +9 more
openaire   +3 more sources

Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state

Biochemistry and Biophysics Reports, 2018
The pathogenic bacterium Brucella abortus codes for a multi-domain dimeric cytoplasmic histidine kinase called LOV-HK, which is a key blue light-activated virulence factor in this microorganism.
Jimena Rinaldi, Ignacio Fernández, Lucía M. Poth, William E. Shepard, Martin Savko, Fernando A. Goldbaum, Sebastián Klinke   +6 more
doaj   +1 more source

Preliminary Study of Resistance Mechanism of Botrytis cinerea to SYAUP-CN-26

Molecules, 2022
SYAUP-CN-26 (1S, 2R-((3-bromophenethyl)amino)-N-(4-chloro-2-trifluoromethylphenyl) cyclohexane-1-sulfonamide) is a novel sulfonamide compound with excellent activity against Botrytis cinerea.
Kai Wang, Huazhong Zhang, Wanying Zhu, Jingnan Peng, Xinghai Li, Yingzi Wang, Zhiqiu Qi   +6 more
doaj   +1 more source