Oligomeric states in sodium ion-dependent regulation of cyanobacterial histidine kinase-2 [PDF]
, 2017 Two-component signal transduction systems (TCSs) consist of sensor histidine kinases and response regulators. TCSs mediate adaptation to environmental changes in bacteria, plants, fungi and protists. Histidine kinase 2 (Hik2) is a sensor histidine kinase
Allen, J +5 more
core +2 more sources
A Unique Sensor Histidine Kinase [PDF]
Journal of Bacteriology, 2009 Sporulation initiation in Bacillus species is controlled by an extended version of two-component signal transduction systems, termed phosphorelay ([4][1]). The cascade of His→Asp→His→Asp phosphotransfer is typically initiated by the ATP-dependent autophosphorylation of the histidine ...
openaire +2 more sources
From meadows to milk to mucosa – adaptation of Streptococcus and Lactococcus species to their nutritional environments [PDF]
, 2011 Lactic acid bacteria (LAB) are indigenous to food-related habitats as well as associated with the mucosal surfaces of animals. The LAB family Streptococcaceae consists of the genera Lactococcus and Streptococcus.
Adab, P. +12 more
core +8 more sources
Elongation factor 2-diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative stress conditions [PDF]
, 2013 Elongation factor-2 (eEF2) catalyzes the movement of the ribosome along the mRNA. A single histidine residue in eEF2 (H715) is modified to form diphthamide. A role for eEF2 in cellular stress responses is highlighted by the fact that eEF2 is sensitive to
Argüelles Castilla, Sandro +3 more
core +1 more source
mBioThe two-component system (TCS) enables bacteria to sense and respond to environmental changes through histidine kinase-mediated signaling cascades. Although the core components of TCSs have been extensively studied, the molecular basis of accessory ...
Piqian Gong +7 more
doaj +1 more source
Biochemistry and Biophysics Reports, 2018 The pathogenic bacterium Brucella abortus codes for a multi-domain dimeric cytoplasmic histidine kinase called LOV-HK, which is a key blue light-activated virulence factor in this microorganism.
Jimena Rinaldi +6 more
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Preliminary Study of Resistance Mechanism of Botrytis cinerea to SYAUP-CN-26
Molecules, 2022 SYAUP-CN-26 (1S, 2R-((3-bromophenethyl)amino)-N-(4-chloro-2-trifluoromethylphenyl) cyclohexane-1-sulfonamide) is a novel sulfonamide compound with excellent activity against Botrytis cinerea.
Kai Wang +6 more
doaj +1 more source
Hybrid histidine kinases in pathogenic fungi [PDF]
Molecular Microbiology, 2015 SummaryHistidine kinases (HK) sense and transduce via phosphorylation events many intra‐ and extracellular signals in bacteria, archaea, slime moulds and plants. HK are also widespread in the fungal kingdom, but their precise roles in the regulation of physiological processes remain largely obscure.
Defosse, Tatiana +9 more
openaire +3 more sources
Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries. [PDF]
, 2016 We identified drug seeds for treating Huntington's disease (HD) by combining in vitro single molecule fluorescence spectroscopy, in silico molecular docking simulations, and in vivo fly and mouse HD models to screen for inhibitors of abnormal ...
Chen, Xigui +17 more
core +2 more sources
Modification of histidine repeat proteins by inorganic polyphosphate
Cell Reports, 2023 Summary: Inorganic polyphosphate (polyP) is a linear polymer of orthophosphate that is present in nearly all organisms studied to date. A remarkable function of polyP involves its attachment to lysine residues via non-enzymatic post-translational ...
Nolan Neville +6 more
doaj +1 more source