Results 21 to 30 of about 150,310 (289)
Cell fate regulation governed by a repurposed bacterial histidine kinase. [PDF]
PLoS Biology, 2014 One of the simplest organisms to divide asymmetrically is the bacterium Caulobacter crescentus. The DivL pseudo-histidine kinase, positioned at one cell pole, regulates cell-fate by controlling the activation of the global transcription factor CtrA via ...
W Seth Childers +6 more
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Visualizing autophosphorylation in histidine kinases [PDF]
Nature Communications, 2014 Reversible protein phosphorylation is the most widespread regulatory mechanism in signal transduction. Autophosphorylation in a dimeric sensor histidine kinase is the first step in two-component signalling, the predominant signal-transduction device in bacteria.
Casino, Patricia +2 more
openaire +3 more sources
Histidine residue 94 is involved in pH sensing by histidine kinase ArsS of Helicobacter pylori. [PDF]
PLoS ONE, 2009 The ArsRS two-component system is the master regulator of acid adaptation in the human gastric pathogen Helicobacter pylori. Low pH is supposed to trigger the autophosphorylation of the histidine kinase ArsS and the subsequent transfer of the phosphoryl ...
Stefanie Müller +2 more
doaj +1 more source
FEBS Open Bio, 2014 Two-component signal transduction systems (TCS), consisting of a sensor histidine protein kinase and its cognate response regulator, are an important mode of environmental sensing in bacteria.
Alisha Dhiman +3 more
doaj +1 more source
Interaction Analysis of a Two-Component System Using Nanodiscs. [PDF]
PLoS ONE, 2016 Two-component systems are the major means by which bacteria couple adaptation to environmental changes. All utilize a phosphorylation cascade from a histidine kinase to a response regulator, and some also employ an accessory protein.
Patrick Hörnschemeyer +4 more
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Structural and chemical requirements for histidine phosphorylation by the chemotaxis kinase CheA [PDF]
, 2005 The CheA histidine kinase initiates the signal transduction pathway of bacterial chemotaxis by autophosphorylating a conserved histidine on its phosphotransferase domain (P1).
Bilwes, Alexandrine M. +6 more
core +1 more source
Nature Communications, 2021 The bacteriophytochrome DrBphP from Deinococcus radiodurans shows high sequence homology to the histidine kinase Agp1 from Agrobacterium fabrum but lacks kinase activity.
Elina Multamäki +12 more
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Mechanism of Regulation of Receptor Histidine Kinases [PDF]
Structure, 2012 Bacterial transmembrane receptors regulate an intracellular catalytic output in response to extracellular sensory input. To investigate the conformational changes that relay the regulatory signal, we have studied the HAMP domain, a ubiquitous intracellular module connecting input to output domains.
Ferris, Hedda U. +8 more
openaire +4 more sources
Peptide vocabulary analysis reveals ultra-conservation and homonymity in protein sequences [PDF]
, 2007 A new algorithm is presented for vocabulary analysis (word detection) in texts of human origin. It performs at 60%–70% overall accuracy and greater than 80% accuracy for longer words, and approximately 85% sensitivity on Alice in Wonderland, a ...
Gatherer, D.
core +4 more sources
How Can a Histidine Kinase Respond to Mechanical Stress?
Frontiers in Microbiology, 2021 Bacteria respond to physical forces perceived as mechanical stress as part of their comprehensive environmental sensing strategy. Histidine kinases can then funnel diverse environmental stimuli into changes in gene expression through a series of ...
Linda J. Kenney
doaj +1 more source