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A Case of Multisystemic Langerhans Cell Histiocytosis in an Adult

Proceedings of Singapore Healthcare, 2011
Langerhans cell histiocytosis is a rare disease in adults with a myriad of clinical presentations. A case of multisystemic Langerhans cell histiocytosis with involvement of bone, skin, lungs, and the hypothalamic-pituitary-axis is reported.
Chiaw Ling Chng MBBS, MRCP
doaj   +2 more sources

Langerhans cell histiocytosis present in a 1-day-old girl: a case report [PDF]

Journal of Medical Case Reports
Background Langerhans cell histiocytosis is a rare condition characterized by diverse clinical manifestations, ranging from cutaneous lesions to systemic involvement.
Yang Meng
doaj   +2 more sources

Langerhans cell histiocytosis in adults: literature review

Онкогематология, 2022
Langerhans cells histiocytosis is a variant of malignant histiocytosis. The course and symptoms vary. patients with localized forms have a better prognosis, because local therapy is effective.
V. G. Potapenko, V. V. Baykov, A. V. Zinchenko, N. A. Potikhonova   +3 more
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Establishment of MOS-SF36 percentile ranks in the general youth French population

BMC Psychology, 2022
Background The SF-36 is a generic quality of life questionnaire, massively translated and widely used to obtain physical and mental health status. However, validation work in the French language was carried out over a generation ago.
Arthur Trognon, Emilie Tinti, Blandine Beaupain, Jean Donadieu, Michel Musiol   +4 more
doaj   +1 more source

ALK-positive histiocytosis involving the cavernous sinus: A deceptive radiologic mimic of meningioma

Radiology Case Reports, 2023
Anaplastic lymphoma kinase (ALK)-positive histiocytosis is an uncommon condition, recently considered a separate condition from other histiocytosis by WHO 5th edition. It can involve intracranial structures.
Mohammadreza Alizadeh, MD, Aishwarya Ravindran, MD, Rati Chkheidze, MD, Gaurav Goyal, MD, Mahdie Hosseini, MD, Parnian Shobeiri, MD, Arezoo Shafieioun, MD, Mohammad Khalafi, MD, Ramin Shahidi, Houman Sotoudeh, MD, Aparna Singhal, MD   +10 more
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Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis

Cell Communication and Signaling, 2022
Langerhans cell histiocytosis (LCH) is an inflammatory myeloid malignancy in the “L-group” histiocytosis. Mitogen-activated protein kinase (MAPK) pathway activating mutations are detectable in nearly all LCH lesions. However, the pathogenic roles of MAPK
Xue-min Gao, Jian Li, Xin-xin Cao
doaj   +1 more source

Radiotherapy in langerhans cell histiocytosis : a rare indication in a rare disease [PDF]

, 2013
Introduction: Langerhans Cell Histiocytosis (LCH) represents a rare benign disorder, previously designated as "Histiocytosis X", "Type II Histiocytosis" or "Langerhans Cell Granulomatosis".
Bruns, Frank, Büntzel, Jens, Eich, Hans Theodor, Haverkamp, Uwe, Heyd, Reinhard, Kriz, Jan, Micke, Oliver, Schäfer, Ulrich, Seegenschmiedt, Heinrich   +8 more
core   +3 more sources

Case Report: ALK-Positive Histiocytosis With KIF5B-ALK Fusion in Cerebrum-Disseminated Lesions in a Child

Frontiers in Oncology, 2022
BackgroundAnaplastic lymphoma kinase (ALK)-positive histiocytosis is a rare type of histiocytosis that could affect multiple systems in children and adults.
Yi Guo, Yi Guo, Hai-bo Qu, Hai-bo Qu, Gang Ning, Gang Ning, Feng-lin Jia, Feng-lin Jia, Hong Liu, Xin-mao Ma, Xin-mao Ma, Yi Liao, Yi Liao   +12 more
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Langerhans cell histiocytosis developing acute lymphoblastic leukemia

SAGE Open Medical Case Reports, 2022
The sequential occurrence of Langerhans cell histiocytosis and acute leukemia in only one individual has been reported previously; however, it is rarely observed that Langerhans cell histiocytosis can transform into acute lymphoblastic leukemia, and the ...
JinFang Zhang, Sa Zong, Bing Liao
doaj   +1 more source

A Recent Update on Histiocytic Disorder in Children: Focus on Diagnosis and Treatment

Clinical Pediatric Hematology-Oncology, 2020
The histiocytosis is rare disorder characterized by the accumulation of macrophages, dendritic cells, or monocyte-derived cells in various tissues and organs of children and adults. Classifying histiocytic disorders is difficult and has changed over time
Hoi Soo Yoon
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