Results 1 to 10 of about 43,228 (269)

Langerhans-Cell Histiocytosis

New England Journal of Medicine, 2018
Langerhans cell histiocytosis (LCH) formerly known as pulmonary eosinophilic granuloma is currently regarded by the World Health Organization as a clonal neoplastic proliferation of histiocytes.
Carl E Allen, Miriam Merad, Kenneth L Mcclain   +2 more
exaly   +5 more sources

Langerhans cell histiocytosis

Blood, 2020
Langerhans Cell Histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction.
Carlos Rodriguez-Galindo, Carl E Allen
exaly   +2 more sources

Langerhans cell histiocytosis present in a 1-day-old girl: a case report [PDF]

Journal of Medical Case Reports
Background Langerhans cell histiocytosis is a rare condition characterized by diverse clinical manifestations, ranging from cutaneous lesions to systemic involvement.
Yang Meng
doaj   +2 more sources

Langerhans cell histiocytosis in adults: Advances in pathophysiology and treatment

Cancer Science, 2018
Langerhans cell histiocytosis (LCH) is a rare systemic disorder characterized by the accumulation of CD1a+/Langerin+ LCH cells and wide‐ranging organ involvement.
Masayuki Kobayashi, Arinobu Tojo
exaly   +2 more sources

Pediatric Cutaneous Anaplastic Lymphoma Kinase-Positive Histiocytosis with DCTN1::ALK Fusion: A Case Report and Literature Search [PDF]

Diagnostics
Background and Clinical Significance: Anaplastic lymphoma kinase (ALK)-positive histiocytosis is a relatively novel entity, affecting single or multiple organ systems; it is characterized by aggregates of neoplastic cells of the histiocytic lineage ...
Kristóf Levente Korpás, Attila Mokánszki, Lívia Beke, Gábor Méhes, Yi-Che Chang Chien   +4 more
doaj   +2 more sources

ALK-positive histiocytosis: an expanded clinicopathologic spectrum and frequent presence of KIF5B-ALK fusion

Modern Pathology, 2018
Kenneth Tou En Chang, Elizabeth Algar
exaly   +2 more sources

International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults

Blood, 2022
Langerhans cell histiocytosis (LCH) can affect children and adults with a wide variety of clinical manifestations, including unifocal, single-system multifocal, single-system pulmonary (smoking-associated), or multisystem disease.
G. Goyal, A. Tazi, R. Go, K. Rech, J. Picarsic, R. Vassallo, Jason R. Young, C. Cox, J. V. van Laar, M. Hermiston, Xin-xin Cao, P. Makras, G. Kaltsas, J. Haroche, M. Collin, K. McClain, E. Diamond, M. Girschikofsky   +17 more
semanticscholar   +1 more source

ALK+ histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition.

Blood, 2021
ALK-related histiocytosis (formerly ALK-positive histiocytosis) is a rare subtype of histiocytic neoplasm first described in 2008 in three infants with multisystemic disease involving the liver and hematopoietic system.
P. Kemps, J. Picarsic, B. Durham, Z. Hélias‐Rodzewicz, L. Hiemcke-Jiwa, C. van den Bos, M. D. van de Wetering, C. V. van Noesel, J. V. van Laar, R. Verdijk, U. Flucke, P. Hogendoorn, F. J. S. H. Woei‐A‐Jin, R. Sciot, A. Beilken, F. Feuerhake, M. Ebinger, R. Möhle, F. Fend, A. Bornemann, V. Wiegering, K. Ernestus, T. Méry, O. Gryniewicz-Kwiatkowska, B. Dembowska-Bagińska, D. Evseev, V. Potapenko, V. Baykov, S. Gaspari, S. Rossi, M. Gessi, G. Tamburrini, S. Héritier, J. Donadieu, Jacinthe Bonneau-Lagacherie, Claire Lamaison, L. Farnault, S. Fraitag, M. Jullie, J. Haroche, M. Collin, J. Allotey, Majid Madni, K. Turner, S. Picton, P. Barbaro, A. Poulin, Ingrid S Tam, D. El Demellawy, Brianna Empringham, J. Whitlock, A. Raghunathan, Amy A. Swanson, M. Suchi, Jon Brandt, N. Yaseen, J. Weinstein, I. Eldem, B. Sisk, V. Sridhar, Mandy M Atkinson, Lucas R. Massoth, J. Hornick, S. Alexandrescu, K. Yeo, K. Petrova-Drus, Stephen Z Peeke, Laura Muñoz-Arcos, D. Leino, D. Grier, R. Lorsbach, Somak Roy, Ashish R. Kumar, Shipra Garg, Nishant Tiwari, K. Schafernak, Michael M. Henry, A. V. van Halteren, O. Abla, E. Diamond, J. Emile   +80 more
semanticscholar   +1 more source

Current understanding and management of pulmonary Langerhans cell histiocytosis

Thorax, 2017
Robert Vassallo, Sergio Harari, Abdellatif Tazi   +2 more
exaly   +2 more sources

CNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH‐associated neurodegeneration and mass lesions

Cancer, 2018
Kenneth L Mcclain, Jennifer L Picarsic, Rikhia Chakraborty   +2 more
exaly   +2 more sources