Results 11 to 20 of about 4,921,202 (211)
Langerhans cell histiocytosis is a rare proliferative disease of histiocyte-like cells, the peak incidence of which occurs in early childhood. Pulmonary Langerhans Cell Histiocytosis is one of the forms of this disease, but it usually affects young ...
Victor V. Fomin +4 more
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Langerhans cell histiocytosis (LCH) is rare unique disorder of the reticuloendothelial system characterized by an abnormal proliferation of histiocytes and eosinophilic leukocytes.
S Jayachandran, N Balaji
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A Case of Multisystemic Langerhans Cell Histiocytosis in an Adult
Langerhans cell histiocytosis is a rare disease in adults with a myriad of clinical presentations. A case of multisystemic Langerhans cell histiocytosis with involvement of bone, skin, lungs, and the hypothalamic-pituitary-axis is reported.
Chiaw Ling Chng MBBS, MRCP
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Langerhans cell histiocytosis (histiocytosis X) [PDF]
There has been a renewed interest in Langerhans cell histiocytosis in recent years due both to advances in basic research and to improvements in diagnostic and treatment approaches.
K Y Lam, Lam, KY
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Ulcerated nodules are often seen in the flexural areas of patients with Langerhans cell histiocytosis, or histiocytosis X (2,5-7). Infants with this condition have widespread cutaneous disease with a seborrheic rash involving the scalp and flexural ...
N. Fazio +4 more
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Langerhans cell histiocytosis [PDF]
The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations. Skin biopsy immunohistochemistry presented positive S100 protein and vimentine, but the diagnosis was done with the demonstration of Birbeck granules with ...
Chauffaille, Maria de Lourdes Lopes Ferrari UNIFESP +10 more
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Langerhans cell histiocytosis [PDF]
Langerhans-Cell Histiocytosis A spectrum of diseases formerly known as histiocytosis X and now called Langerhans-cell histiocytosis is characterized by ERK pathway activation (including BRAF V600E ...
Kumar, Manish, Menon, Anil S
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Late-Onset Langerhans Cell Histiocytosis Presenting with Seizures and Bilateral Temporal Involvement
Langerhans cell histiocytosis is known as a rare childhood disease. In this case, we wanted to share our patient’s experience whose first symptom was an epileptic seizure, which attracted attention at an advanced age and revealed bilateral temporal lobe ...
Özge Öcek, Hasan Kuş, Pınar Ortan
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Langerhans Cell Histiocytosis [PDF]
Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone disease to a life-threatening multisystem condition. LCH can occur at any age but is more frequent in the pediatric population. A neoplastic origin of this disease has been suggested
Giovannetti, Filippo +7 more
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Langerhans cell histiocytosis [PDF]
Abstract Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction. The pathogenic cells are defined by constitutive activation of the MAPK signaling pathway.
Carl E. Allen, Carlos Rodriguez-Galindo
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