Results 21 to 30 of about 55,121 (305)

A Recent Update on Histiocytic Disorder in Children: Focus on Diagnosis and Treatment

Clinical Pediatric Hematology-Oncology, 2020
The histiocytosis is rare disorder characterized by the accumulation of macrophages, dendritic cells, or monocyte-derived cells in various tissues and organs of children and adults. Classifying histiocytic disorders is difficult and has changed over time
Hoi Soo Yoon
doaj   +1 more source

Immune Thrombocytopenia Revealing Enriched IgG-4 Peri-Renal Rosai-Dorfman Disease Successfully Treated with Rituximab: A Case Report and Literature Review.

Frontiers in Medicine, 2021
Immune thrombocytopenia (ITP) is a rare autoimmune-mediated condition characterized by isolated thrombocytopenia (<100 G/L) after exclusion of other causes.
Jerome Razanamahery, Sebastien Humbert, Jean-Francois Emile, Fleur Cohen-Aubart, Jean Fontan, Philippe Maksud, Sylvain Audia, Julien Haroche   +7 more
doaj   +1 more source

Childhood Langerhans cell histiocytosis with severe lung involvement: a nationwide cohort study

Orphanet Journal of Rare Diseases, 2020
Background Lung involvement in childhood Langerhans cell histiocytosis (LCH) is infrequent and rarely life threatening, but occasionally, severe presentations are observed. Methods Among 1482 children (
Solenne Le Louet, Mohamed-Aziz Barkaoui, Jean Miron, Claire Galambrun, Nathalie Aladjidi, Pascal Chastagner, Kamila Kebaili, Corinne Armari-Alla, Anne Lambilliotte, Julien Lejeune, Despina Moshous, Valeria Della Valle, Chiara Sileo, Hubert Ducou Le Pointe, Jean-François Chateil, Sylvain Renolleau, Jean-Eudes Piloquet, Aurelie Portefaix, Ralph Epaud, Raphaël Chiron, Emmanuelle Bugnet, Gwenaël Lorillon, Abdelatif Tazi, Jean-François Emile, Jean Donadieu, Sébastien Héritier   +25 more
doaj   +1 more source

Challenges in the diagnosis of hemophagocytic lymphohistiocytosis: Recommendations from the North American Consortium for Histiocytosis (NACHO)

Pediatric Blood & Cancer, 2019
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of pathologic immune activation, often associated with genetic defects of lymphocyte cytotoxicity.
M. Jordan, C. Allen, Jay Greenberg, Michael M. Henry, M. Hermiston, Ashish R. Kumar, M. Hines, O. Eckstein, S. Ladisch, K. Nichols, C. Rodríguez-Galindo, B. Wistinghausen, K. McClain   +12 more
semanticscholar   +1 more source

Primary Langerhans Cell Histiocytosis of the Extrahepatic Bile Duct Occurring in an Adult Patient

Balkan Medical Journal, 2018
Background: Langerhans cell histiocytosis is characterized by an abnormal proliferation of neoplastic Langerhans cells. Langerhans cell histiocytosis commonly affects the pediatric population, whereas presentation in adults remains a rare event.
Ifeyinwa E. Obiorah, Alicia Henao Velasquez, Bhaskar Kallakury, Metin Özdemirli   +3 more
doaj   +1 more source

Benign TdT-positive cells in pediatric and adult lymph nodes: a potential diagnostic pitfall [PDF]

, 2018
Benign TdT-positive cells have been documented in a variety of non-hematopoietic tissues. Scant data are however available on their presence in non-neoplastic lymph nodes.
AGOSTINELLI, CLAUDIO, Bertuzzi, Clara, BRIGNOLA, STEFANO, Pillon, Marta, Pizzi, Marco, Righi, Simona, Rugge, Massimo, Sabattini, Elena, Semenzato, Gianpietro   +8 more
core   +1 more source

Vemurafenib for Refractory Multisystem Langerhans Cell Histiocytosis in Children: An International Observational Study

Journal of Clinical Oncology, 2019
PURPOSE Off-label use of vemurafenib (VMF) to treat BRAFV600E mutation–positive, refractory, childhood Langerhans cell histiocytosis (LCH) was evaluated. PATIENTS AND METHODS Fifty-four patients from 12 countries took VMF 20 mg/kg/d. They were classified
J. Donadieu, I. Larabi, M. Tardieu, J. Visser, C. Hutter, E. Sieni, N. Kabbara, M. Barkaoui, Jean Miron, F. Chalard, Paul Milne, J. Haroche, F. Cohen, Z. Hélias‐Rodzewicz, N. Simon, M. Jehanne, A. Kolenová, A. Pagnier, N. Aladjidi, P. Schneider, G. Plat, A. Lutun, Anne Sonntagbauer, T. Lehrnbecher, A. Ferster, V. Efremova, M. Ahlmann, Laurence Blanc, J. Nicholson, A. Lambilliote, H. Boudiaf, A. Lissat, K. Svojgr, Fanette Bernard, S. Elitzur, M. Golan, D. Evseev, M. Maschan, A. Idbaih, O. Slater, M. Minkov, V. Taly, M. Collin, J. Alvarez, J. Emile, S. Héritier   +45 more
semanticscholar   +1 more source

Adult Langerhans cell histiocytosis presenting with multisystem involvement and sarcomatoid features: a case report

Journal of Medical Case Reports, 2020
Background Langerhans cell tumors are rare clonal disorders characterized by neoplastic proliferation of dendritic cells that can be further classified into the subtypes Langerhans cell histiocytosis and Langerhans cell sarcoma, which are rare neoplasms ...
Luis E. Aguirre, Ingrid Schwartz, Jennifer Chapman, Marcelo F. Larsen, Alvaro Alencar   +4 more
doaj   +1 more source

Cytophagic Histiocytic Panniculitis (CHP) in a Patient with SLE Found after Autopsy: When a Rash Is "Complicated!" [PDF]

, 2019
Introduction: Cytophagic histolytic panniculitis (CHP) is a clinical disorder characterized by nodular panniculitis of the subcutaneous adipose tissue. It was first described in 1980 by Winkelmann.
Abbas, Hafsa, Aslam, Ahsan, Chilimuri, Sridhar, Niazi, Masooma, Saad, Muhammad   +4 more
core   +1 more source

Langerhans cell histiocytosis (histiocytosis X) [PDF]

Postgraduate Medical Journal, 1997
Summary There has been a renewed interest in Langerhans cell histiocytosis in recent years due both to advances in basic research and to improvements in diagnostic and treatment approaches. In this article, we review the various aspects of the disease and the potential implications of these recent scientific researches for our ...
openaire   +3 more sources