Results 1 to 10 of about 5,633,398 (171)

"Histiocytosis X" – A Rare Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Histiocytosis X is an idiopathic disease, characterized by a disorder of the reticulo-endothelial system in the human body. Histopathological studies carried out right from the 1800s have seen a significant similarity in the pathologic process of ...
Emmanuel Dhiravia Sargunam Azariah, Deepak Chandrasekaran, Ravindran Chinnaswami, Sivaramakrishnan Balasubramaniam, Eswari Jagdish   +4 more
doaj   +2 more sources

Unusual presentation of histiocytosis X in the cranial vault: A rare case report [PDF]

Radiology Case Reports
Langerhans histiocytosis or histiocytosis X is an oligo-clonal proliferation of Langerhans cells. We report the case of an 11-month-old infant who had presented with a parieto-occipital swelling since birth, which progressively increased in volume ...
Dahmane El Hairech, MD, PhDs, Nadia El Kadmiri, PhD   +1 more
doaj   +2 more sources

Histiocytosis X and Bronchopulmonary Adenocarcinoma: A Rare Coexistence [PDF]

Canadian Respiratory Journal, 2002
There exists a rarely observed association between pulmonary histiocytosis X and bronchopulmonary cancer. However, the frequency of bronchopulmonary cancer in these patients is higher than in the general population.
Akýn Kaya, Ýsmail Savas, Elif Pen, Serpil Dizbay Sak, Adem Gungor, Uður Gonullu   +5 more
doaj   +2 more sources

Targeted proteomics reveal histiocytosis-associated neurodegeneration signatures. [PDF]

Hemasphere
Abstract Neurodegeneration (ND) is a severe complication of Langerhans cell histiocytosis (LCH), yet its underlying biology and reliable biomarkers remain poorly defined. The aim of this study was to (1) gain insight into neuroimmunological mechanisms governing ND and (2) assess the clinical value of established and novel biomarkers for ND‐LCH.
Kvedaraite E, Lourda M, Munting JB, Papo M, Jädersten M, Shioda Y, Sakamoto K, Muñoz DM, Andriopoulos P, Pegoraro F, Laurencikas E, Kühnle I, Wille J, Naeije L, Olkinuora H, Sinha I, Hagey DW, Olsson-Åkefeldt S, Cohen-Aubart F, Österlundh G, Svensson M, Idbaih A, Piehl F, Blennow K, Zetterberg H, von Bahr TG, Gavhed D, Morimoto A, Haroche J, Henter JI.   +29 more
europepmc   +2 more sources

Progressive Cerebellar Dysfunction, Pituitary Insufficiency, and Severe Skeletal Fragility in Adult Survivorship of Childhood Multisystem Langerhans Cell Histiocytosis: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Childhood‐onset multisystem Langerhans cell histiocytosis can lead to delayed adult morbidity involving the neurologic, hypothalamic–pituitary, and skeletal systems. Progressive cerebellar dysfunction, chronic pituitary insufficiency, and severe skeletal fragility may emerge years after apparent disease control, underscoring the need for ...
Alnahar S, Senjab A, Gharib S, Gharib Z, Hadid L.   +4 more
europepmc   +2 more sources

Histiocytosis development and clinical variation through the lens of genomics. [PDF]

J Pathol
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Kemps PG, van Halteren AG, van Wezel T, Hogendoorn PC.   +3 more
europepmc   +2 more sources

Outcome of treatment with trametinib in adults with histiocytic neoplasms in the United Kingdom. [PDF]

Br J Haematol
Trametinib (MEK inhibitor) shows efficacy in refractory and high‐risk adult histiocytic neoplasms. At a median follow‐up of 21.4 months, the clinical response rate was 81% (30/37) and the radiological response was 68% (25/37) (n = 37).
Amerikanou R, Munir T, Bowles K, McNamara C, Chavda N, Price E, Adiyodi J, Coles A, Kelsey P, Smith J, Adams R, Hussein H, Zhao R, Nguyen T, Collin M, Gohil S.   +15 more
europepmc   +2 more sources

Multisystem Langerhans cell histiocytosis: Literature review and case report

Radiology Case Reports, 2022
Langerhans cell histiocytosis (LCH) refers to a group of diseases of unknown etiology, typically discovered in childhood, characterized by the accumulation of Langerhans cells (white blood cells with large cell nuclei that may contain cytoplasmic ...
Cung-Van Cong, MD, PhD, Tran-Thi Ly, PhD, Nguyen Minh Duc, MD   +2 more
doaj   +1 more source

Langerhans cell histiocytosis (histiocytosis x) – in the mandible

Brazilian Dental Science, 2013
This article reports a case of 65 year-old man consultedin a private radiology dental clinic for a panoramicradiography, where was indicated a radiolucent area,extending into the periapical region of the teeth 35 to 43 to the base of the mandible ...
Angela Jordão Camargo, Mayara Cheade, Celso Martinelli, Solange Aparecida Caldeira Monteiro, Christiano de Oliveira Santos, Plauto Christopher Aranha Watanabe   +5 more
doaj   +1 more source

Hand-Schüller-Christian disease

Indian Journal of Dental Research, 2012
Langerhan cell histiocytosis, formerly known as histiocytosis X, traditionally denotes a group of diseases that stem from proliferative reticuloendothelial disturbances.The etiology and pathogenesis of the disease remain debatable.
Deepak Bhargava, Kalyani Bhargava, Vinay Hazarey, Sindhu Milind Ganvir   +3 more
doaj   +1 more source