Results 111 to 120 of about 249,831 (220)
Affinity Discrimination in B cells in Response to Membrane Antigen Requires Kinetic Proofreading [PDF]
arXiv, 2010 B cells signaling in response to antigen is proportional to antigen affinity, a process known as affinity discrimination. Recent research suggests that B cells can acquire antigen in membrane-bound form on the surface of antigen-presenting cells (APCs), with signaling being initiated within a few seconds of B cell/APC contact.
arxiv
Revisiting the role of histo-blood group antigens in rotavirus host-cell invasion [PDF]
Nature Communications, 2015 Histo-blood group antigens (HBGAs) have been proposed as rotavirus receptors. H type-1 and Lewis(b) antigens have been reported to bind VP8* from major human rotavirus genotypes P[4], P[6] and P[8], while VP8* from a rarer P[14] rotavirus recognizes A-type HBGAs.
Boehm, Raphael +7 more
openaire +3 more sources
ANZ Journal of Surgery, Volume 94, Issue 11, Page 1925-1934, November 2024.Titanium is commonly used as a pure metal or as part of an alloy for a range of medical implants. In orthopaedic surgery, this includes trauma and joint replacement components. This article explores immune‐mediated reactions to titanium and the evidence‐based underpinning its claim as a hypoallergenic option.
Arnold Chen, Andrew P. Kurmis
wiley +1 more source
Norovirus Gastroenteritis Outbreak with a Secretor-independent Susceptibility Pattern, Sweden
Emerging Infectious Diseases, 2010 Norovirus (NoV) is recognized as the commonest cause of acute gastroenteritis among adults. Susceptibility to disease has been associated with histo-blood group antigens and secretor status; nonsecretors are almost completely resistant to disease.
Johan Nordgren +4 more
doaj +1 more source
Frontiers in Immunology, 2020 A number of epidemiological studies have evaluated the potential association between H. pylori and cardiovascular disease, but with contrasting results.
Riccardo Negrini +3 more
doaj +1 more source
Integrating influenza antigenic dynamics with molecular evolution [PDF]
arXiv, 2013 Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between influenza strains using the hemagglutination inhibition (HI) assay.
arxiv
Immunological Reviews, Volume 328, Issue 1, Page 243-264, November 2024.Summary Enteric viruses are the main cause of acute gastroenteritis worldwide with a significant morbidity and mortality, especially among children and aged adults. Some enteric viruses also cause disseminated infections and severe neurological manifestations such as poliomyelitis.
Quentin Riller +4 more
wiley +1 more source
mBio, 2020 Human noroviruses (HuNoVs) are the leading cause of nonbacterial gastroenteritis worldwide. Histo-blood group antigen (HBGA) expression is an important susceptibility factor for HuNoV infection based on controlled human infection models and epidemiologic
Kei Haga +12 more
doaj +1 more source
Model for Diversity Analysis of Antigen Receptor Repertoires [PDF]
arXiv, 2010 In most of the recent immunological literature the differences across antigen receptor populations are examined via non-parametric statistical measures of species overlap and diversity borrowed from ecological studies. While this approach is robust in a wide range of situations, it seems to provide little insight into the underlying clonal size ...
arxiv
Prediction, dynamics, and visualization of antigenic phenotypes of seasonal influenza viruses [PDF]
, 2015 Human seasonal influenza viruses evolve rapidly, enabling the virus population to evade immunity and re-infect previously infected individuals. Antigenic properties are largely determined by the surface glycoprotein hemagglutinin (HA) and amino acid substitutions at exposed epitope sites in HA mediate loss of recognition by antibodies.
arxiv +1 more source